Sorry to hear about your dog. There have been some discussions about pets and Nicotinamide Riboside. Oakman has used various supplement routines with their cats which has included Curcumin for at least one of their cats, in addition to what is mentioned below in the quote. I will guess that some might work for dogs. Did your veterinarian have you change your Jack Russell's diet due to Pancreatitis? It can be hard to tell in a small dog sometimes, but are they overweight?
Niki, Oakman's cat:
"UPDATE: Niki is doing REALLY well!
It's been about two months since I 1st posted Niki's story and what Niagen (and her joint supplement) had seemingly been doing for her. In June, she had regained a good amount of strength and vitality, but still had a significant, obvious limp on her front leg. I had been giving a calculated 25-30 mg of NR (that is, not including filler) daily. I decided to cut her dose to once every 2nd or 3rd day in mid July due to a mild nervous tick she began exhibiting, and I changed her joint supplement to something with more ingredients I thought would help her condition. She gets (1/4 dose) of this only on a day NR is not given, but again on an every 2nd or 3rd day basis.
Due to the heat here (steady 90-100 degrees) we decided to get her a shot at the vet 1st week of August, as she had begun to scratch a bit in one spot. It was not bad like before, but I think the hot weather was getting to her. In total it had been 6 months since her last shot, rather than the 4-6 weeks before. Hopefully, she should be good to go for the rest of the summer, and hopefully 6 months or longer... Time will tell.
In describing to the vet what I had been doing for her, he was not able to either confirm or deny the effects of the supplementation, but he said there was no dispute that something major had changed in her condition. But I wanted to tell her story (to the vet and here on the forum) as I think it offers some insight about the effects of NR may be in animals. As a cat is completely oblivious to what is being given to them, the results are real, unbiased, but of course anecdotal. The vet said no study of this NR effect would ever happen as it's not worth it to invest in a study like that on felines, unfortunately.
But the best news for Niki (and me) is that this new dosing and supplement combo has produced pretty dramatic results. That is, her limp is now unnoticeable, her appetite is so strong that we are now restricting her diet to keep her from gaining too much weight (now 9lbs, up from 8lbs), and her mood and activity level have remained better than before. The supplement combo, now using much reduced amounts, seems to be working even better. I think I may have successfully stuffed another couple lives into her regularly allotted nine!
http://www.longecity...iki-and-niagen/
A thread about N.R. with a side track discussing the possible use of N.R. in a dog. I do not know what they did.
http://www.longecity...es-again/page-9
Edited by Heisok, 03 February 2018 - 05:22 PM.