27 replies to this topic

[s123]

Can somebody tell me something about insulin blockers?
Insulin is the hormone of aging.
Can we use a insulin blocker to keep insulin levels low?
And is it safe to use?

[Shepard]

Before you decide to figure out a way to block insulin, you should probably buy life insurance and pick out a coffin.

[david ellis]

Pretty good shot Shepard. [lol]

S123,

Insulin is released to remove glucose from the blood. All carbohydrates, complex and simple, become glucose in the blood, so a low carb diet will minimize the release of insulin. Also fasting, say, eating every other day, or 30% less every day will drive the release of insulin even lower. All tough choices, and many are deciding its worth the effort.

[shifter]

Although its involved in the aging process, you would have a much shorter lifespan without it. I managed to sustain a dibetic mouse once for 8 months on daily insulin injections. Without them it would have been dead in 3-4 weeks max so obviously insulin does something right

[s123]

Of course insulin does something right. But it’s harmful in high levels. That’s why I ask if their’s a supplement that lowers insulin to a level that’s not too low but is enough to your metabolism to work properly.
Like david ellis said an low carb diet can lower your insulin levels. And some people practise this diet. Thus it’s possible to reduce your insulin levels to a level that is not to low so that you stay alive.

Healthy persons have a insulin level (I couldn’t find the exact numbers immediate so it’s not the correct numbers, the numbers are only to sketch what I want to say) between 10 and 100. I have a level of let’s say 40. It’s in the normal range but it’s higher than the doses that my body need. So can I reduce this number to let’s say 20 (also in the normal range) by taking a supplement?

[Shepard]

Insulin levels are a reflection of your metabolism.

You should change your question to "What methods lower my body's need for insulin?".

[eternaltraveler]

Before you decide to figure out a way to block insulin, you should probably buy life insurance and pick out a coffin.

[lol]

[s123]

Insulin levels are a reflection of your metabolism.

You should change your question to "What methods lower my body's need for insulin?".

And what's the answer to this question?

[Shepard]

If I thoroughly answer the question, I'll be selling it as a book. But, your number one choice is going to be calorie restriction. Than go from there to exploring different types of exercise, macronutrient manipulation, lifestyle factors, specific foods or supplementation manipulation, etc. etc. etc.

I'd probably rank those four things in that order, too.

[s123]

I'm on CR.

[Mixter]

You can, in addition to CR, try 1) insulin senistizers and 2) carb/fat absorbing
things in that case, which should be more what you what... But those things don't
directly act on insulin, but reduce glucose level spikes, thereby requiring less insulin.

1) Would be oral antidiabetics such as metformin/acarbose... ALA, CLA a little bit, too
metformin, acarbose and others work but are 'heavy stuff' -- if you are on CR already,
they are probably unnecessary, just staying on CR will be fine. also you can get into
hypoglycemia when taking those and your blood sugar+insulin already is low -> BAD

2) Would be eating a lot of fiber (PolyGlucoPlex is best to also absorb some carbs
directly), and maybe starch blockers (phaseolines), to get a really slow glucose
absorption and thus even slower and lower insulin response. BUT, again, I'm pretty
unsure how meaningful that is if you already are and will stay on CR...

[Matt]

DR fontana measured insulin in CRers and it was around 1.4, extremely insulin sensitive. I think the reference range is like 5–20 mU/L. So if you you're doing CR, then you don't really need anything to help lower insulin even more.

[rfarris]

So can I reduce this [bG] number to let’s say 20 (also in the normal range) by taking a supplement?

Be very careful. Once you get to 40, you're in the seizure range. Wouldn't want that to happen as you drive down the road. They'd take away your drivers license.

[s123]

When you drink fruit juice, your insulin levels will rise. But I have heard a trick to overcome this problem. Mix some protein in your fruit juice.
Is this a good idea?

[AlexCanada]

How does one prevent Insulin from getting too high??  My chronic low cortisol and high insulin cause me to be a constant state of Hypoglycemia, intense hunger, frequent urination, negativity, cognitive problems, sluggish energy and worthless life. 

 

I could severely use some insulin reduction and generally more stable blood sugar.  Consuming more sugary foods just skyrockets my insulin levels and the opposite effect is often achieved. 

Edited by AlexCanada, 17 December 2015 - 03:31 AM.

[maxwatt]

Metformin

 

[AlexCanada]

Metformin

 

Thanks. I been meaning to get it.   It is my next thing to try when I see my doctor in January. Hopefully he will prescribe.  Do nootropic shops at all sell it? 

[aconita]

If your insulin is constantly high your lifestyle has to change, you probably don't like to hear that therefore drugs will be your only option left: not a smart choice indeed.

[maxwatt]

 

Metformin

 

Thanks. I been meaning to get it.   It is my next thing to try when I see my doctor in January. Hopefully he will prescribe.  Do nootropic shops at all sell it? 

 

 

Berberine has a similar effect to insulin, which is enhanced with baicalin.  Add some chlorogenic acid, scutellaria herb and either resveratrol or ferulic acid, as this should promote healthy glucose levels in those cases where it is elevated.  works well in mice.  Metformin can be bought online from Indian pharmacies who are rather loose regarding prescriptions, and customs are not likely to seize it.  There is a very slight risk of potentially fatal lactic acidosis, which is why they like to have a doctor monitor it.  Mushrooms tend to lower blood sugar, cremini, porcini or white buttons, shiitaki doesn't do this so much though the have other benefits.  Red wine in moderation lowers blood sugar.  5 to 10 ounces with a meal depending on your size and tolerance.   Eating cheese or nuts for snacks should satisfy without spiking blood sugar.  Vigorous aerobic exercise that elevates the pulse to 130 or more will tend to lower one's fasting blood glucose when engaged in on an ongoing basis.  Avoid white rice and bread.  Eat no sugar-added foods, nothing with added fructose either,   Fruit in extreme moderation, berries are OK.  Avoid long term use of opiates (causes hypogonadatropic hypogonadism, which leads over time to elevated blood sugar and diabetes, as well as hypothyroidism.  Interferes with the pituitary axis.)  It is possible that fluoride in drinking water contributes to diabetes risk, it definitely correlates with hypothyroidism.

 

That's all I can think of off the top of my head.

Edited by maxwatt, 17 December 2015 - 08:29 PM.

[AlexCanada]

If your insulin is constantly high your lifestyle has to change, you probably don't like to hear that therefore drugs will be your only option left: not a smart choice indeed.

 

I assure you my lifestyle is not the problem. I have been damaged by accutane, resveratrol and suffer from low cortisol, super low testosterone, low estrogen, hypoglycemia, low dopamine (catecholamine testing or whatever it's called), supressed ACTH and problems across the board. I am 5'7 and weigh 118. I am not physically out of shape by any means.  My body is not able to produce proper hormones on it's own. And controlling my blood sugar is not easy either.

 

I eat healthier than most, work out sufficiently without much benefit. I do not smoke, do not drink, do not engage in any unhealthy activity.  It's just my reality.

[AlexCanada]

 

 

Metformin

 

Thanks. I been meaning to get it.   It is my next thing to try when I see my doctor in January. Hopefully he will prescribe.  Do nootropic shops at all sell it? 

 

 

Berberine has a similar effect to insulin, which is enhanced with baicalin.  Add some chlorogenic acid, scutellaria herb and either resveratrol or ferulic acid, as this should promote healthy glucose levels in those cases where it is elevated.  works well in mice.  Metformin can be bought online from Indian pharmacies who are rather loose regarding prescriptions, and customs are not likely to seize it.  There is a very slight risk of potentially fatal lactic acidosis, which is why they like to have a doctor monitor it.  Mushrooms tend to lower blood sugar, cremini, porcini or white buttons, shiitaki doesn't do this so much though the have other benefits.  Red wine in moderation lowers blood sugar.  5 to 10 ounces with a meal depending on your size and tolerance.   Eating cheese or nuts for snacks should satisfy without spiking blood sugar.  Vigorous aerobic exercise that elevates the pulse to 130 or more will tend to lower one's fasting blood glucose when engaged in on an ongoing basis.  Avoid white rice and bread.  Eat no sugar-added foods, nothing with added fructose either,   Fruit in extreme moderation, berries are OK.  Avoid long term use of opiates (causes hypogonadatropic hypogonadism, which leads over time to elevated blood sugar and diabetes, as well as hypothyroidism.  Interferes with the pituitary axis.)  It is possible that fluoride in drinking water contributes to diabetes risk, it definitely correlates with hypothyroidism.

 

That's all I can think of off the top of my head.

 

 

Thank you so much for the wealth of information.  Are most of these primarily for lowering blood sugar or do some modulate/balance blood sugar as well?  My problem generally is with low blood sugar rather than high.

 

I been replacing white rice and replacing rye and sourdough bread w glutino gluten free bread. As I am not sure what regular breads would be good for me. Occassionally will indulge in regular breads/buns but not often. 

 

Resveratrol used to help me for mood and general health few years ago but eventually wrecked havoc on my collagen/copper levels and possibly other factors.  Ended up with collagen loss on my face (profound wrinkles near eyes) and loss of feeling in certain areas of my finger tips.  

[Multivitz]

Sounds like this guy has a tiered Liver. Get a balance by going Ketogenic. Zinc and Molybdenum, (Selenium??) are keys to you goals, but you've read The Magnesium Miracle right?
Chromium might help!?
AVOID BAD GLUTEN!!!
Get a quality multivitamin and start your self on a quarter dose, because it sounds like you are really low and weak. Start exercise with a gentle walk, vigorous exercises should be avoided until you see fit. A Silica will help all the junk fall into place and as for your parasites, they run away when your body starts working again. Rub on some Essential oil that has been diluted in Almond oil that works, Oregano?
I don't know what you need, only you can tell the importance of your symptoms. An Amino Acid complex might be needed to kick start your digestion after all Insulin is made of over 40 different amino acids!
Magnesium Malate will lift a mood but so will vitamin D3, agian, start it on quarter dosing 100iu, say every 3 days to find a balance that lifts you up gently
You can get vigerous in your own time.

Edited by Multivitz, 18 December 2015 - 11:24 AM.

[Multivitz]

Starving the immune cells of suger is a sure way to allow parasite to thrive. Their byproducts have many symptoms and their effect on ones mind can cause all sorts of beliefs. You'll see what I mean when you start looking into it. Insulin blockers indeed....

[Multivitz]

To get sensitive to insulin again apart from the parasite thing, Lyposomal type supplements work wonders, just start them on quarter dose unless you want to nail down a deficiency by suspected symptoms. Lets say you think you are low in something and so you take an atagonist that is known to be involved in that same system, symptoms would get worse, that would allow preperation of foods/supplememts to embark on a course.
Olive Leaf Extract would DROP insulin like a stone, because it cleans the cell wall by its antioxidant action, the cells need repair after (L-Lysine, Zinc, Mag, etc) though or you won't feel better.

[Multivitz]

Phosphotidyl Choline(rebiulds the body along with D3!!!!) is used for many amazing things in your body. It is used to make hormones, amino acids do to. L-Taurine may come in handy, L-Methionine can boost, and stretching upon waking is essential. Soon you can get yourself back to normal. The salts act a catalysts and energisers. Your Chi makes them work better and longer. Don't starve your self , or anyone else!

Edited by Multivitz, 18 December 2015 - 12:00 PM.

[IWS]

Have a look at the Jiaogulan (Gynostemma Pentaphyllum) extract, it's pretty effective in respect to insulin sensitivity etc.

[aconita]

Instead of focusing on insulin I'd rather try to figure out what's wrong in the bigger picture, a picture where all hormones seems to be extremely low but insulin deserves something more than just an insulin blocker because even given that an effective way to reduce insulin will be implemented the quality of life/health would unlikely be much better anyway, therefore therapeutically focusing on insulin is kind of pointless in my view.

 

When somebody health is a wreck but keeps stating that there is nothing wrong with the actual lifestyle I am kind of puzzled...

 

[LC-f]

If you are interested in supplements that can lower your insulin you can check my post were I tested on myself influence of different supplements on fasting insulin

 

http://www.longecity...-blood-results/