26 replies to this topic

[lucid]

So that this thread will be easy to browse please use the following format:

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Approximation of Blood work before begining Resveratrol:
Core Body Temperature: 98.7 F
Weight: 240 lbs
Height: 6'5

Triglycerides: 330
HDL Cholesterol: 20
LDL Cholesterol: 140
VLDL Cholesterol: 50

Note:This an aproximation of what I remember my results being. (Not looking at lab work sheet)

Other Drugs / Sups Taken:

*****************************************
Blood work after Taking Resveratrol for 6 Months
Dosage: 3g Resv EtOH + Peg3350

Core Body Temperature: 97.5 F
Weight: 230 lbs
Height: 6'5

Triglycerides: 211
HDL Cholesterol: 33
LDL Cholesterol: 100
VLDL Cholesterol: 44

Notes: Just got lab work done, I was really disappointed in HDL and Triglycerides, but I had been taking accutane for 2 weeks @ the time. Also increased ammount of excercise.
Other Drugs / Sups Taken effecting info: Niacin (.5g/day), Fish Oil (3g/day), Cocoa(5g/day on average), accutane (makes almost all numbers 30-40% worse)

Oops posted to sup forum: Please move to Resv. Subforum.

Edited by lucid, 28 January 2008 - 05:42 PM.

[inawe]

Weight: 240 lbs -> 230 lbs. Didn't lower it much.
Height: 6'5 -> 6'5. Didn't lower it any.

[mikeinnaples]

Oddly, my body core temperature has gone down from 98.5 avg to 97.4

I wouldn't exepct cholesterol, especially of the genetic sort to be affected by resveratrol. The 1g of niacin I take a day and simvastatin did the trick with that though.

[neogenic]

Oddly, my body core temperature has gone down from 98.5 avg to 97.4

I wouldn't exepct cholesterol, especially of the genetic sort to be affected by resveratrol. The 1g of niacin I take a day and simvastatin did the trick with that though.

I would think the Niacin and Fish Oil have more to do with those numbers than resveratrol.

[StrangeAeons]

FWIW about the temps, even after my first dose of 100mg Res I felt substantially more "cold-natured"

[missminni]

Oddly, my body core temperature has gone down from 98.5 avg to 97.4

I wouldn't exepct cholesterol, especially of the genetic sort to be affected by resveratrol. The 1g of niacin I take a day and simvastatin did the trick with that though.

I just took my temerature and its 97.4 as well. It used to be 98.6. Has resveratrol
been observed to lower body temperature? Is that a good thing?

[niner]

Oddly, my body core temperature has gone down from 98.5 avg to 97.4

I wouldn't exepct cholesterol, especially of the genetic sort to be affected by resveratrol. The 1g of niacin I take a day and simvastatin did the trick with that though.

I just took my temerature and its 97.4 as well. It used to be 98.6. Has resveratrol
been observed to lower body temperature? Is that a good thing?

Lower body temperature is associated with longevity.

[sUper GeNius]

Oddly, my body core temperature has gone down from 98.5 avg to 97.4

I wouldn't exepct cholesterol, especially of the genetic sort to be affected by resveratrol. The 1g of niacin I take a day and simvastatin did the trick with that though.

I just took my temerature and its 97.4 as well. It used to be 98.6. Has resveratrol
been observed to lower body temperature? Is that a good thing?

I believe it's been shown, that if you decrease an animals temperature, it lives longer. Tough to do with warm-blooded mammals and birds, as it's regulated in the brain.

[missminni]

Oddly, my body core temperature has gone down from 98.5 avg to 97.4

I wouldn't exepct cholesterol, especially of the genetic sort to be affected by resveratrol. The 1g of niacin I take a day and simvastatin did the trick with that though.

I just took my temerature and its 97.4 as well. It used to be 98.6. Has resveratrol
been observed to lower body temperature? Is that a good thing?

Lower body temperature is associated with longevity.

That's what I thought. At least we know it's working.

]wikipedia - Low body temperature increases lifespan
It was long theorised that low body temperature may prolong life. On November 2006, a team of scientists from the Scripps Research Institute reported that transgenic mice which had body temperature 0.3-0.5 C lower than normal mice (due to overexpressing the uncoupling protein 2 in hypocretin neurons (Hcrt-UCP2), which elevated hypothalamic temperature, thus forcing the hypothalamus to lower body temperature) indeed lived longer than normal mice. The lifespan was 12% longer for males and 20% longer for females. Mice were allowed to eat as much as they wanted. [17] [18] [19] The effects of body temperature on longevity have not been studied in humans.

Edited by missminni, 28 January 2008 - 11:18 PM.

[lucid]

CR is well documented to decrease core body temperature. Monkeys in this study had about a 1 degree Fahrenheit reduction in core body temperature.
http://www.pnas.org/...tract/93/9/4159

Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents.
Many studies of caloric restriction (CR) in rodents and lower animals indicate that this nutritional manipulation retards aging processes, as evidenced by increased longevity, reduced pathology, and maintenance of physiological function in a more youthful state. The anti-aging effects of CR are believed to relate, at least in part, to changes in energy metabolism. We are attempting to determine whether similar effects occur in response to CR in nonhuman primates. Core (rectal) body temperature decreased progressively with age from 2 to 30 years in rhesus monkeys fed ad lib (controls) and is reduced by approx 0.5°C in age-matched monkeys subjected to 6 years of a 30% reduction in caloric intake. A short-term (1 month) 30% restriction of 2.5-year-old monkeys lowered subcutaneous body temperature by 1.0°C. Indirect calorimetry showed that 24-hr energy expenditure was reduced by approximately 24% during short-term CR. The temporal association between reduced body temperature and energy expenditure suggests that reductions in body temperature relate to the induction of an energy conservation mechanism during CR. These reductions in body temperature and energy expenditure are consistent with findings in rodent studies in which aging rate was retarded by CR, now strengthening the possibility that CR may exert beneficial effects in primates analogous to those observed in rodents.

Note that body temperatures fluctuate throughout the day: (I have observed this temperature change many times however)

Hopefully some of you have before and after blood work to post. I am going to have mine taken again in 3 months, then I will be off accutane and hopefully I can see a 50+ HDL reading and a <120 Triglyceride reading. (my family has a terrible triglyceride disposition.)

Edited by lucid, 29 January 2008 - 05:00 PM.

[missminni]

Note that body temperatures fluctuate throughout the day: (I have observed this temperature change many times however)

Mine did already. I'm 98.5 now.

[mike250]

I'm just wondering if the low body temps long term would cause an impaired thyroid output.

[lucid]

I had my thyroid measured and its fine. Given 6 months isn't that long term...

[Matt]

I'm on CR, you can see how my thyroid slowly drops so does my body temp
http://www.matthewla...com/results.htm

Lately my body temperature is around 36.0 degrees Celsius (tympanic reading) over 9 readings during the day.



Though it doesn't state how low temperature was in males in humans.

[shuffleup]

Other Drugs / Sups Taken effecting info: Niacin (.5g/day), Fish Oil (3g/day), Cocoa(5g/day on average), accutane (makes almost all numbers 30-40% worse)

Maybe up the fish oil to double what you are taking to help with the TRIGs, along with lower-carb diet? I took 5 g's of fih oil for less than a month,reduced carbs <100g/day and dropped trigs from 150-ish to 113.

Niacin can take a year to see full benefits i read on the track your plaque site.

[lucid]

I was hoping some other people would have some before and after results to post. Anyone else thinking about getting their blood work done?

[niner]

I was hoping some other people would have some before and after results to post. Anyone else thinking about getting their blood work done?

I'm getting some blood work done in a few weeks, but I'm not sure it would be that meaningful to compare it to before I started using resveratrol because I've had other things going on, like losing a fair amount of weight, spending a lot of time in the gym, and, um, spending a month in the ICU, unconscious, on a ventilator... (legionnaire's disease, a really bad bacterial pneumonia) aside from that, everything was pretty normal. (I'm healthier than ever now, FWIW)

[ilanso]

I'm getting some blood work done in a few weeks, but I'm not sure it would be that meaningful to compare it to before I started using resveratrol because I've had other things going on, like losing a fair amount of weight, spending a lot of time in the gym, and, um, spending a month in the ICU, unconscious, on a ventilator... (legionnaire's disease, a really bad bacterial pneumonia) aside from that, everything was pretty normal. (I'm healthier than ever now, FWIW)

Sorry to hear you had it so bad - that stuff is scary. Glad to have you back unscathed. I assume the lifestyle changes were made post-ICU and meant among other things to strengthen your immune system.
I guess my unanswered question of two weeks ago ( http://www.imminst.o...o...st&p=219208 ) about your diet/anti-glycation plan for HBA1C shall remain untested for now (you've obviously agressively moved on both variables).

[rhc124]

No change in my body temp but I have always been in the upper 97's. I'll know more after my yearly exam monday.

[tintinet]

I performed this test years ago, when I started taking Longevinex, so pretty low dose (about 40 mg/day with old formulation.) Measured basal body temp upon waking. But it started at 97.5 and stayed put.

[Shepard]

I'm just wondering if the low body temps long term would cause an impaired thyroid output.

It's more likely that the lower body temperature correlated with longevity is due to lowered thyroid output, which is due to lowered energy intake. I wouldn't put too much stock in having poor thyroid output or a lower body temperature unless you were on a CR diet.

[lucid]

I'm just wondering if the low body temps long term would cause an impaired thyroid output.

It's more likely that the lower body temperature correlated with longevity is due to lowered thyroid output, which is due to lowered energy intake. I wouldn't put too much stock in having poor thyroid output or a lower body temperature unless you were on a CR diet.

It looks like you may be right:
http://www.nature.co...re05354_T1.html
Mice on a high calorie diet had increased body temperatures whether being fed Resv or not.

[bixbyte]

Sorry, I do not have any early Blood Work at home
I started taking RSV years ago
I might be able to ask my MD for old blood test results if needed.


Blood work after Taking Resveratrol for many Years
Dosage: 2g (+ or more) Res + Peg 3350, aspirin, mobic, methyl silycilate, naringran, Grapefruit juice, bioperine

Body Temperature: 98.9 F
Weight: 182 lbs (dropped from 198 to 200 pounds)
Height: 6'

Triglycerides: 199
HDL Cholesterol: 29
LDL Cholesterol: 143

Total Cholesterol: 212

Glucose: 90

Hemoglobin: 11.8

Blood Pressure: 130/72 range I take it a couple times a day

(Working on raising my HDL)
I just started Flush Free Niacin 500 mg/day

Doctor said I am anemic but he is not worried

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Edited by bixbyte, 04 February 2008 - 02:10 AM.

[sUper GeNius]

Sorry, I do not have any early Blood Work at home
I started taking RSV years ago
I might be able to ask my MD for old blood test results if needed.


Blood work after Taking Resveratrol for many Years
Dosage: 2g (+ or more) Res + Peg 3350, aspirin, mobic, methyl silycilate, naringran, Grapefruit juice, bioperine

Body Temperature: 98.9 F
Weight: 182 lbs (dropped from 198 to 200 pounds)
Height: 6'

Triglycerides: 199
HDL Cholesterol: 29
LDL Cholesterol: 143

Total Cholesterol: 212

Glucose: 90

Hemoglobin: 11.8

(Working on raising my HDL)
I just started Flush Free Niacin 500 mg/day

Doctor said I am anemic but he is not worried

______________________________________________________________________________

Your LDL is high. Tri"s a little high too. How's your BP?

Edited by FuLL meMbeR, 03 February 2008 - 10:32 PM.

[tintinet]

Bix-

are you on a low carb diet? Low carb skied my HDL to 105 mg/dl from 65; Total cholesterol 151 mg/dl; TG 55 mg/dl.

Edited by tintinet, 04 February 2008 - 12:09 AM.

[bixbyte]

Your LDL is high. Tri"s a little high too. How's your BP?

BP has been steady at 130/72 range sometimes the 130 or 72 runs lower
I have my own BP guage.
My BP in the MD office immediately after two cups of Coffee and a cereal bar was 132/82
But it usually runs at 130/72 on my own BP guage.

[bixbyte]

Bix-

are you on a low carb diet? Low carb skied my HDL to 105 mg/dl from 65; Total cholesterol 151 mg/dl; TG 55 mg/dl.

Not a low carb diet, but I reduced my carb intake.

I eliminated the white sugar in my daily coffee intake with splenda for over one year.
Anecdotal evidence is the Res appears to have decreased my Weight and Glucose.
My BMI and Glucose are very good.
IMHO, the RSV is preventing diabetes but for heart disease prevention I need adjuncts.
I know my glucose, trigylcerides and weight were slightly elevated most my adult life.

Even with Res my blood needs Fish Oil and flush free Niacin to help with the Lipids.
After 3 or 4 months of Flush Free Niacin I'll have a new Blood test.
Also, I think the FFN is raising my Body Temp, All my life my BT has always been one degree below 98.6 (=97.6)
Flush Free makes me feel warm and my face is always slightly flushed.
Maybe I need a different supplement to fix my lipids?

Edited by bixbyte, 04 February 2008 - 04:49 PM.