I am on Suboxone, typically prescribed for opiate addition, for chronic pain. I take 4 mgs 3 times a day. In addition to chronic pain I also have mild-moderate depression and am weaning of SSRIs.
I started Perkia St. Johns Wort 3 times a day and stopped after reading the following:
What drug(s) may interact with Buprenorphine (Suboxone)?
• medicines for fungal infections (examples: fluconazole, itraconazole, ketoconazole, voriconazole)
• medicines for seizures
• mifepristone, RU-486
• some medicines used to treat HIV infection or AIDS
• St. John's wort
I was really disappointed as I wanted to replace my SSRI w/ St. Johns Wort. What type of interaction would occur? Is it a toxicity issue or an issue of one drug not being metobolized? I know there are some knowledgeable people on these forums so I thought you might be able to help me out. I did try St. Johns Wort for 6 days and ended up w/ a nasty withdrawal leading me to believe St. Johns Wort interacts strongly w/ Suboxone.
Can someone with knowledge in pharmacology comment? I’ll take educated guesses!