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Resveratrol, IF, and Calorie Restriction


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#1 sUper GeNius

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Posted 07 June 2008 - 10:03 PM


Okay everybody, a few obvious questions.


If one want to live as long as possible, what is the best course, short of full-blown CR. I live a life with too physical activity I believe for continuous CR.

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?

Is t-res supplementation likely to cancel any benefit from intermittent CR?

Is t-res likely to compliment CR?

How much t-res is wise to take at this time?

Edited by FuLL meMbeR, 07 June 2008 - 10:06 PM.


#2 Mind

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Posted 08 June 2008 - 12:42 AM

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?


From what I have seen written by other members and my own experience, intermittent fasting is much easier and allows for a higher amount of physical activity. Paul Wakfer does intermittent fasting instead of CR. Not sure how resv would augment IF, if at all.

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#3 sUper GeNius

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Posted 08 June 2008 - 12:49 AM

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?


From what I have seen written by other members and my own experience, intermittent fasting is much easier and allows for a higher amount of physical activity. Paul Wakfer does intermittent fasting instead of CR. Not sure how resv would augment IF, if at all.


How intermittent are you doing it? Every other day? I know Paul does take resv, Orchid brand. Any idea how much he takes?

#4 tintinet

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Posted 08 June 2008 - 02:11 AM

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?


From what I have seen written by other members and my own experience, intermittent fasting is much easier and allows for a higher amount of physical activity. Paul Wakfer does intermittent fasting instead of CR. Not sure how resv would augment IF, if at all.


How intermittent are you doing it? Every other day? I know Paul does take resv, Orchid brand. Any idea how much he takes?


Paul's regimen

Edited by tintinet, 08 June 2008 - 02:11 AM.


#5 sUper GeNius

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Posted 08 June 2008 - 03:01 AM

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?


From what I have seen written by other members and my own experience, intermittent fasting is much easier and allows for a higher amount of physical activity. Paul Wakfer does intermittent fasting instead of CR. Not sure how resv would augment IF, if at all.


How intermittent are you doing it? Every other day? I know Paul does take resv, Orchid brand. Any idea how much he takes?


Paul's regimen



it looks like he is doing 20-4 CR. One meal a day. From what I have read, that method has the least evidence behind it. Am i correct?

#6 edward

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Posted 08 June 2008 - 05:45 PM

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?


From what I have seen written by other members and my own experience, intermittent fasting is much easier and allows for a higher amount of physical activity. Paul Wakfer does intermittent fasting instead of CR. Not sure how resv would augment IF, if at all.


How intermittent are you doing it? Every other day? I know Paul does take resv, Orchid brand. Any idea how much he takes?


Paul's regimen



it looks like he is doing 20-4 CR. One meal a day. From what I have read, that method has the least evidence behind it. Am i correct?


20-4 IF (I dont know how many calories he eats and his body requirements as such he may be doing 20-4 IF with CR built in). From what I have read the 20-4 regimine is the least promising of the IF schedules. Some version of the 24 fast, 24 Eat best mimics the rat studies, I think the 20 fast then 4 hour pig out (necessary if one is to get enough calories to make it not CR) just cant be that healthy.

#7 forever freedom

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Posted 08 June 2008 - 06:23 PM

I think that the best method of IF is fasting every other day. Or fasting for 32 hours (24h + 8h of sleep) and eating for 16 hours.


As for mixing resveratrol in the equation, i have no idea. But i don't think that it would hurt either, so why not? After all these regimens and even taking supps to live longer nothing of these are proven to radically extend human lifespan so we are really just living guinea pigs, testing whatever is available in the hopes that it will work. There is no definite answer as to what's the ideal mix of regimen + supps because unfortunately no one knows it yet.

#8 edward

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Posted 08 June 2008 - 06:55 PM

I think that the best method of IF is fasting every other day. Or fasting for 32 hours (24h + 8h of sleep) and eating for 16 hours.
snip...


Have you tried this method? I have, its a little rough even after being low-carb adapted (easier to fast if your body is used to burning its own and external fat). I've also tried the 20-4 (pretty easy but human studies dont support its efficacy) and the 24 eat 24 fast (ie fast from 6pm day 1 till 6pm day 2 (or whatever cut off time you choose, noon works good too) then eat 6pm till 6pm) this seems to be easier and approximates the rats schedule better.

#9 sUper GeNius

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Posted 08 June 2008 - 09:06 PM

I think that the best method of IF is fasting every other day. Or fasting for 32 hours (24h + 8h of sleep) and eating for 16 hours.
snip...


Have you tried this method? I have, its a little rough even after being low-carb adapted (easier to fast if your body is used to burning its own and external fat). I've also tried the 20-4 (pretty easy but human studies dont support its efficacy) and the 24 eat 24 fast (ie fast from 6pm day 1 till 6pm day 2 (or whatever cut off time you choose, noon works good too) then eat 6pm till 6pm) this seems to be easier and approximates the rats schedule better.


Isn't what you are proposing almost exactly the same as 20-4? Biggest differnce is that your fast is 24 hrs vs 20 hrs. However you eat a full day as well.

I have read about one study doing 20-4, where certain biomarkers much improved.

#10 edward

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Posted 08 June 2008 - 11:23 PM

I think that the best method of IF is fasting every other day. Or fasting for 32 hours (24h + 8h of sleep) and eating for 16 hours.
snip...


Have you tried this method? I have, its a little rough even after being low-carb adapted (easier to fast if your body is used to burning its own and external fat). I've also tried the 20-4 (pretty easy but human studies dont support its efficacy) and the 24 eat 24 fast (ie fast from 6pm day 1 till 6pm day 2 (or whatever cut off time you choose, noon works good too) then eat 6pm till 6pm) this seems to be easier and approximates the rats schedule better.


Isn't what you are proposing almost exactly the same as 20-4? Biggest differnce is that your fast is 24 hrs vs 20 hrs. However you eat a full day as well.

I have read about one study doing 20-4, where certain biomarkers much improved.

No, there is a 24 hour fast then you eat half of one day and half of the other day. The total amount of eating time is longer and seperated by sleep (mini fast) so therefore you are not taking in all your calorie requirements for a day in 4 hours.

Say your cut off is noon (which works best for me). Then day 1 you fast from lunch of day 1 until lunch of day 2. Then you eat from noon until bedtime for me 11 pm (usually) then you wake up and continue eating until noon. Then you fast until noon the next day and repeat. Therefore you are eating at night and in the morning, not eating all your calories at night in 4 hours everyday and then going to sleep which seems to me to be one of the big issues. Eating 2000 calories at night in 4 hours then going to sleep doesnt seem like a good situation.

#11 edward

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Posted 08 June 2008 - 11:26 PM

Note, I am still tweaking my eating as I find it a bit too restrictive (and I lose too much weight) if I do my low carb with IF, I like carbs, but dont feel well when I eat them (sleepy) so it is a work in progress.

#12 dsbuffa

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Posted 09 June 2008 - 01:57 AM

Okay everybody, a few obvious questions.


If one want to live as long as possible, what is the best course, short of full-blown CR. I live a life with too physical activity I believe for continuous CR.

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?

Is t-res supplementation likely to cancel any benefit from intermittent CR?

Is t-res likely to compliment CR?

How much t-res is wise to take at this time?


I'm jumping in on the IF with the 20 hour fast and 4 hour eating window. I have been doing it for 2 years and three months and can say I have lost 76 pounds. My sense of smell has enhanced. I have had a cyst in my right breast and 3 cysts on my ovaries disappear in a 2 year time period. It also has helped with getting rid of my sweet tooth. I don't eat anything that does not have a high nutritional value. I'm like crazy about it now. Which is a big change from the person that was addicted to Pepsi and ice cream. LOL It is just a really easy diet to follow. Now this is only a one rat study, but I recommend it to everyone as a good way to get bad eating habits under control and a little weight loss.

Now all that being said I am playing with doing a 36 hour fast instead, because a lot of the stuff I have read about IF seems this is the best window. Still working out the logistics. I did stop eating at 7pm one day..... nothing the next and ate 7am the next morning. Well that didn't work out well. I don't really like eating in the morning now that I have been doing one evening meal for so long. So this 36 hour fast I am going to have my usual couple of cups of coffee in the morning to break my fast..... maybe something light for lunch and work up to a good dinner. Kind of a day rest between the 36 hour fasting periods. It's just and experiement... if I don't like it I am quickly going back to 20/4.

As for the Resveratrol.... I don't have a clue. I like to eat my vitamins. I love a glass of red wine and to eat grapes. It just gives me more reason to enjoy these two things. It might not contain enough resveratrol to make a difference, but I'm not overdosing on it either. LOL

Life is a jouney... Enjoy it!

Dyan

#13 sUper GeNius

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Posted 09 June 2008 - 03:53 AM

I'm jumping in on the IF with the 20 hour fast and 4 hour eating window. I have been doing it for 2 years and three months and can say I have lost 76 pounds. My sense of smell has enhanced. I have had a cyst in my right breast and 3 cysts on my ovaries disappear in a 2 year time period. It also has helped with getting rid of my sweet tooth. I don't eat anything that does not have a high nutritional value. I'm like crazy about it now. Which is a big change from the person that was addicted to Pepsi and ice cream. LOL It is just a really easy diet to follow. Now this is only a one rat study, but I recommend it to everyone as a good way to get bad eating habits under control and a little weight loss.

Now all that being said I am playing with doing a 36 hour fast instead, because a lot of the stuff I have read about IF seems this is the best window. Still working out the logistics. I did stop eating at 7pm one day..... nothing the next and ate 7am the next morning. Well that didn't work out well. I don't really like eating in the morning now that I have been doing one evening meal for so long. So this 36 hour fast I am going to have my usual couple of cups of coffee in the morning to break my fast..... maybe something light for lunch and work up to a good dinner.
(snip)

Dyan
[/quote]

You mean you consider a cup of coffee as breaking your fast? What about black coffee? I can't give up my coffee. I read that many drink tea on fasting days.

I could easily do 20-4. I do sort of an 18-6 now, not feeling that I need t eat until later in the day. My issue with it as a CR tool, well quite frankly, I'm afraid that it just won't work. Unless you reduce calories enough to lose weight, alot of weight, to bring yourself 15-25% below what you weighed at around 20 yrs old.

Edited by FuLL meMbeR, 09 June 2008 - 03:53 AM.


#14 edward

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Posted 09 June 2008 - 09:38 PM

Most IF literature I have read doesn't consider black coffee, green tea, etc to be breaking the fast as they are virtually calorie free. When I fast I drink coffee, tea and take some supplements which have also have a negligible caloric content (I stay away from Amino Acids, Fish Oil and the like). But someone else said and I agree, I don't think calories have to be 0 just close.

We should continue this discussion in the Intermittent Fasting Club thread, perhaps some nice navigator could move this thread there? http://www.imminst.o...lub-t21426.html

#15 sUper GeNius

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Posted 09 June 2008 - 10:10 PM

Most IF literature I have read doesn't consider black coffee, green tea, etc to be breaking the fast as they are virtually calorie free. When I fast I drink coffee, tea and take some supplements which have also have a negligible caloric content (I stay away from Amino Acids, Fish Oil and the like). But someone else said and I agree, I don't think calories have to be 0 just close.

We should continue this discussion in the Intermittent Fasting Club thread, perhaps some nice navigator could move this thread there? http://www.imminst.o...lub-t21426.html


I googled the composition of drip brewed coffee using a paper filter. It contains just a tiny bit of oil. I think I would agree with you then. Using a metal scree filter increases the oil content a bit, and percolation increase the oild content alot.

#16 eldar

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Posted 10 June 2008 - 07:33 AM

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?


From what I have seen written by other members and my own experience, intermittent fasting is much easier and allows for a higher amount of physical activity. Paul Wakfer does intermittent fasting instead of CR. Not sure how resv would augment IF, if at all.


Paul Wakfer also eats 1950 calories a day so he is doing CR too... Which is actually what I believe most with this one meal per day schedule are doing, since it is nearly impossible to eat normal amounts of calories in one meal.

#17 edward

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Posted 10 June 2008 - 10:01 PM

What is the best form of intemittent CR? Every other day fasting? Every other week CR? Every other day CR?


From what I have seen written by other members and my own experience, intermittent fasting is much easier and allows for a higher amount of physical activity. Paul Wakfer does intermittent fasting instead of CR. Not sure how resv would augment IF, if at all.


Paul Wakfer also eats 1950 calories a day so he is doing CR too... Which is actually what I believe most with this one meal per day schedule are doing, since it is nearly impossible to eat normal amounts of calories in one meal.


Maybe not, depends on his age, height/weight and activity level. 1950 may not be CR for him I dont know

#18 sUper GeNius

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Posted 10 June 2008 - 11:56 PM

This is the course of action I've decided on now. Please read this post first:

http://www.imminst.o...&...st&p=244659


I just started the 24 hr periodic fasting. 6pm to 6pm fast, and then the next day 6pm to 6pm of eating, with sufficient caloric intake to lose some weight, with the end result being very moderate CR.

I'll add an assortment of high-value supplements, including t-res, pycnogenol, some vitamin D, (not too much.) benfotamine, some pomegranate juice, maybe a blueberry concentrate, some curcumin, and green tea and green tea extract. Oh, and some raw cocoa powder ad an occasional multivitamin. Add to the mix a decent amount of exercise,and I'll be all set.

#19 edward

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Posted 12 June 2008 - 03:04 AM

This is the course of action I've decided on now. Please read this post first:

http://www.imminst.o...&...st&p=244659


I just started the 24 hr periodic fasting. 6pm to 6pm fast, and then the next day 6pm to 6pm of eating, with sufficient caloric intake to lose some weight, with the end result being very moderate CR.

I'll add an assortment of high-value supplements, including t-res, pycnogenol, some vitamin D, (not too much.) benfotamine, some pomegranate juice, maybe a blueberry concentrate, some curcumin, and green tea and green tea extract. Oh, and some raw cocoa powder ad an occasional multivitamin. Add to the mix a decent amount of exercise,and I'll be all set.


Sounds like a good plan, you might also like to try 1pm to 1pm (ie lunch) as your cut off, it gives you a little more time to eat your afternoon/evening meals on eat days, just see what works best for you.

#20 sUper GeNius

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Posted 12 June 2008 - 04:34 AM

t.[/quote]

Sounds like a good plan, you might also like to try 1pm to 1pm (ie lunch) as your cut off, it gives you a little more time to eat your afternoon/evening meals on eat days, just see what works best for you.
[/quote]

The cpm cutoff is very easy or me. In the past, I have often waited until 3 or 4 pm to have my first meal. This new eating plan is absurdly easy for me, to the point that I worry it won't have any efficacy. Hard to see how something this easy will extend my life. :~

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#21 dsbuffa

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Posted 17 June 2008 - 06:53 PM

You mean you consider a cup of coffee as breaking your fast? What about black coffee? I can't give up my coffee. I read that many drink tea on fasting days.


No I don't consider the coffee breaking my fast. I start every morning with coffee.... 2 cups. I just find the beginning of my eating window I don't really want to eat in the morning or I feel yucky all day. So I have my usual two cups of coffee and about lunch time I have a lite lunch and save my bigger meal for that day for dinner.

Dyan




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