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What about other genes?


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#1 DaffyDuck

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Posted 21 July 2008 - 01:09 PM


The main goal is to mimic calorie restriction. Has this been discussed here?

http://www.eurekaler...i-srd042607.php

Loss of only one of the genes, a gene encoding the protein PHA-4, negated the lifespan-enhancing effect of calorie-restriction in worms. And, when researchers undertook the opposite experiment—by overexpressing pha-4 in worms—the longevity effect was enhanced. “PHA-4 acts completely independent of insulin/IGF-1 signaling and turns out to be essential for CR-mediated longevity,” says Panowski.


Is Resveratrol only a partial mimic for CR and there are other pieces of the puzzle yet to be tested? Where is this research leading currently?




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