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Andy Milonakis Is 33 but looks 14


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#31 Ben Simon

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Posted 01 April 2009 - 12:59 AM

I gotta agree with The Fountain here guys. I know that intuitively the idea that he's somehow 'not aging' seems preposterous. And yes, I'm pretty sure there's a great degree of damage going on under the surface that we don't know about. BUT his case is very strange and very interesting regardless. At the least he has excessive reserves of collagen and elastin in his skin (he's overweight so looks that young? pulease. fat thirty three year olds don't look twenty), and i'm throwing in as saying there's more going on than that. It's simple - even with a developmental disorder it should not be possible to look that young. He should look like a sick thirty three year old, but instead he looks like a healthy teenager. That should not be possible.


I agree with everything you said, accept that he looks 20. he looks 15 max.

Oh and he looks as healthy as an obese teenager can look.


I didn't say he looks twenty. I said overweight thirty three year olds don't look twenty, which they would if being overweight made you look your developmental age, which it doesn't.

#32 TheFountain

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Posted 01 April 2009 - 01:33 AM

I gotta agree with The Fountain here guys. I know that intuitively the idea that he's somehow 'not aging' seems preposterous. And yes, I'm pretty sure there's a great degree of damage going on under the surface that we don't know about. BUT his case is very strange and very interesting regardless. At the least he has excessive reserves of collagen and elastin in his skin (he's overweight so looks that young? pulease. fat thirty three year olds don't look twenty), and i'm throwing in as saying there's more going on than that. It's simple - even with a developmental disorder it should not be possible to look that young. He should look like a sick thirty three year old, but instead he looks like a healthy teenager. That should not be possible.


I agree with everything you said, accept that he looks 20. he looks 15 max.

Oh and he looks as healthy as an obese teenager can look.


I didn't say he looks twenty. I said overweight thirty three year olds don't look twenty, which they would if being overweight made you look your developmental age, which it doesn't.

What do you mean by 'developmental age'? Do you mean that obesity should be considered an adolescent developmental disorder that most adults should naturally overcome in a world where all things are balanced or do you mean something else?

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#33 Ben Simon

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Posted 01 April 2009 - 03:11 AM

I gotta agree with The Fountain here guys. I know that intuitively the idea that he's somehow 'not aging' seems preposterous. And yes, I'm pretty sure there's a great degree of damage going on under the surface that we don't know about. BUT his case is very strange and very interesting regardless. At the least he has excessive reserves of collagen and elastin in his skin (he's overweight so looks that young? pulease. fat thirty three year olds don't look twenty), and i'm throwing in as saying there's more going on than that. It's simple - even with a developmental disorder it should not be possible to look that young. He should look like a sick thirty three year old, but instead he looks like a healthy teenager. That should not be possible.


I agree with everything you said, accept that he looks 20. he looks 15 max.

Oh and he looks as healthy as an obese teenager can look.


I didn't say he looks twenty. I said overweight thirty three year olds don't look twenty, which they would if being overweight made you look your developmental age, which it doesn't.

What do you mean by 'developmental age'? Do you mean that obesity should be considered an adolescent developmental disorder that most adults should naturally overcome in a world where all things are balanced or do you mean something else?


Huh? No. Not at all. How'd you get that?

I mean that earlier someone said the reason Milonakis's skin looks so good is that he is overweight. I'm saying that if that were true, all thirty three year old fat people would look twenty, which is their developmental age. In the sense that development ceases around twenty, and the changes we observe from that point on are degenerative.

#34 TheFountain

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Posted 01 April 2009 - 04:45 AM

I gotta agree with The Fountain here guys. I know that intuitively the idea that he's somehow 'not aging' seems preposterous. And yes, I'm pretty sure there's a great degree of damage going on under the surface that we don't know about. BUT his case is very strange and very interesting regardless. At the least he has excessive reserves of collagen and elastin in his skin (he's overweight so looks that young? pulease. fat thirty three year olds don't look twenty), and i'm throwing in as saying there's more going on than that. It's simple - even with a developmental disorder it should not be possible to look that young. He should look like a sick thirty three year old, but instead he looks like a healthy teenager. That should not be possible.


I agree with everything you said, accept that he looks 20. he looks 15 max.

Oh and he looks as healthy as an obese teenager can look.


I didn't say he looks twenty. I said overweight thirty three year olds don't look twenty, which they would if being overweight made you look your developmental age, which it doesn't.

What do you mean by 'developmental age'? Do you mean that obesity should be considered an adolescent developmental disorder that most adults should naturally overcome in a world where all things are balanced or do you mean something else?


Huh? No. Not at all. How'd you get that?

I mean that earlier someone said the reason Milonakis's skin looks so good is that he is overweight. I'm saying that if that were true, all thirty three year old fat people would look twenty, which is their developmental age. In the sense that development ceases around twenty, and the changes we observe from that point on are degenerative.

Ah so in in other words it is quite possible that andy milonakis has yet to reach his developmental age, for if he had he'd show outward signs thereof.

#35 Ben Simon

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Posted 01 April 2009 - 09:33 AM

I gotta agree with The Fountain here guys. I know that intuitively the idea that he's somehow 'not aging' seems preposterous. And yes, I'm pretty sure there's a great degree of damage going on under the surface that we don't know about. BUT his case is very strange and very interesting regardless. At the least he has excessive reserves of collagen and elastin in his skin (he's overweight so looks that young? pulease. fat thirty three year olds don't look twenty), and i'm throwing in as saying there's more going on than that. It's simple - even with a developmental disorder it should not be possible to look that young. He should look like a sick thirty three year old, but instead he looks like a healthy teenager. That should not be possible.


I agree with everything you said, accept that he looks 20. he looks 15 max.

Oh and he looks as healthy as an obese teenager can look.


I didn't say he looks twenty. I said overweight thirty three year olds don't look twenty, which they would if being overweight made you look your developmental age, which it doesn't.

What do you mean by 'developmental age'? Do you mean that obesity should be considered an adolescent developmental disorder that most adults should naturally overcome in a world where all things are balanced or do you mean something else?


Huh? No. Not at all. How'd you get that?

I mean that earlier someone said the reason Milonakis's skin looks so good is that he is overweight. I'm saying that if that were true, all thirty three year old fat people would look twenty, which is their developmental age. In the sense that development ceases around twenty, and the changes we observe from that point on are degenerative.

Ah so in in other words it is quite possible that andy milonakis has yet to reach his developmental age, for if he had he'd show outward signs thereof.


Not quite. Andy has almost certainly reached his highest developmental age possible. It's just that for most of us that limit is around twenty while for him it was the developmental biology of a teenager. However, the process of senescence starts when we're infants - it's not linked to our developmental age (or not really). It's an accumulative byproduct of our constantly working metabolism. In other words, he should have the damaged skin of a thirty three year old by now, even though developmentally he's a teen - but he doesn't. For some reason he has the skin of a teenager as well as the developmental properties of one! Something very strange is going on. Could it be epigenetic? If so, WTF?

#36 nowayout

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Posted 01 April 2009 - 12:41 PM

In other words, he should have the damaged skin of a thirty three year old by now, even though developmentally he's a teen - but he doesn't.


I don't know why you guys keep repeating this as if it were accepted fact. Many 30-year olds have flawless skin. I am not saying all do, or that people on average do, but many do. It is not uncommon. Again, to prevent another repeated misinterpretation of my statement, I am not saying you do, or any of your friends do, but many do, and I know some who do.

People are not hamsters. Saying Mr. Milonakis should be studied as if he were a lab animal ignores this and is rather insulting to his humanity. Of course it would be interesting to know what is going on. To me it would be just as interesting (i.e. mildly interesting) to know what is going on with those developmentally normal people I have mentioned who have flawless skin at 30. It would be much more interesting to know why some people have flawless skin at 40, but I suspect the answer has more to do with sun exposure and avoidance of changes in weight than anything really fundamental.

Edited by andre, 01 April 2009 - 12:47 PM.


#37 Ben Simon

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Posted 01 April 2009 - 01:04 PM

I don't know why you guys keep repeating this as if it were accepted fact. Many 30-year olds have flawless skin. I am not saying all do, or that people on average do, but many do. It is not uncommon. Again, to prevent another repeated misinterpretation of my statement, I am not saying you do, or any of your friends do, but many do, and I know some who do.


Flawless skin? Or the skin of a prepubescent boy? Cause Milonakis has the latter. Seriously - a thirty three year old guy with an aging disorder that makes him appear to be around the age of fourteen has seemingly childlike skin, and you're prepared to dismiss this offhand as coincidence? As for repeated misinterpretation, when have I interpreted you? I've understood you just fine. I just don't think your explanation is sufficient to account for Milonakis appearance.

People are not hamsters. Saying Mr. Milonakis should be studied as if he were a lab animal ignores this and is rather insulting to his humanity.


Lol. 'Studied as if he were a lab animal'? What does that even mean? Does it mean studied? Like, the way patients with conditions of interest are studied all the time? ...What's the problem with that? It's not like anyones gonna be keeping him in a cage and feeding him pellets.

#38 nowayout

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Posted 01 April 2009 - 01:26 PM

Flawless skin? Or the skin of a prepubescent boy? Cause Milonakis has the latter.


You guys keep confusing development with aging. If he were female, nobody would be saying that he looks so much younger. In fact, his face looks very much like that of millions of 30-year old overweight females. Nobody is clamoring for studying them to uncover the secrets of anti-aging.

People are not hamsters. Saying Mr. Milonakis should be studied as if he were a lab animal ignores this and is rather insulting to his humanity.


Lol. 'Studied as if he were a lab animal'? What does that even mean? Does it mean studied? Like, the way patients with conditions of interest are studied all the time? ...What's the problem with that?


I rest my case.

Edited by andre, 01 April 2009 - 01:29 PM.


#39 Ben Simon

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Posted 01 April 2009 - 02:29 PM

You guys keep confusing development with aging. If he were female, nobody would be saying that he looks so much younger. In fact, his face looks very much like that of millions of 30-year old overweight females. Nobody is clamoring for studying them to uncover the secrets of anti-aging.


Haven't confused the two once. Show me even one thirty three year old with skin that looks like Andy's. And yes, I would most certainly feel the same way if this were a female we were talking about. Even accepting that there might be a rare case of a thirty three year old with skin equivalent to a prepubescent, they'd have to be pretty damn rare. You don't think it might be a coincidence worth investigating that a guy with one incredibly rare condition that keeps him looking fourteen years old just happens to also have another condition that keeps his skin looking the exact same age, well into his thirties? ...No? Then you're not very curious.

I rest my case.


You really shouldn't, because it's incredibly flimsy. People participate in studies all the time. It doesn't dehumanise them at all. They provide their consent and are treated well. Seriously, how do you think we learn most of what we know about human biology?

Edited by ben, 01 April 2009 - 02:30 PM.


#40 Matt

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Posted 01 April 2009 - 02:49 PM

Haven't confused the two once. Show me even one thirty three year old with skin that looks like Andy's.



I've never seen anyone in their 30's like Andy, he simply has child like skin. Skin can be flawless but you can still look your age, I know people like this. So I understand what you mean Ben. It's not like we're talking about he looks 'fairly' young for his age, no, you immediately think hes 15 or something. Where as the difference is that some, very few actually, 30 + year olds have a much more mature look, as well as skin damage like forehead lines, lines under eyes, skin discolourations. I think that over time when we grow the skin changes the ratio of type 3 and type 1 collagen. A childs skin is more type III, whereas adults has more type I collagen.

Hes over 30 years old, he should have many visible signs of aging by now, but he doesn't. This would be a good investigation to see why. Don't GHKO mice have their lifespan extended? Obviously most of us can see he's fat, but his body more resisant to the damage of his lifestyle

I don't know what Planet andre is from, but I've never seen someone look so young like Andy. Flawless skin or not. Aging of the skin starts in your early to mid 20's in the majority of people. I live in the UK that doesn't have great sunny weather either, and you can clearly see damaged skin if you look close enough.

#41 VidX

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Posted 01 April 2009 - 02:51 PM

There's another guy, can't remember his name now (he's a pretyy well known actor) with this condition. And he's well over 40 now, has these childish features, but looks old at the same time too...


If you're referring to gary coleman then I think you are getting ahead of yourself as I believe his condition is somewhat different than Andy Milonakis as it bears more resemblance to dwarfism. And with regard to what you said about 'cutting' someones balls off to get the same features. This guy is a known womanizer in hollywood, he has 5 children from several different women, so he is quite efficacious in the sexual department which kind of throws your theory out the window.

Well being fertile isn't the same as having high/low test levels. I'm not saying it's 100% true, but one of the options.


And yes - Gary, but I know now that it's a different condition. 

Though it's very strange there are almost no detailed info/theories about what's happening with him (I mean - yeah, hormone deficiency, but that's a perfect example of finding out what genes/pathways aren't activated in his body or something.. I'm not a genetic specialist, just thinkin' loud..). I mean - aren't there ANY scientists that would be interested to at least make some basic tests? That's just ridiculous.

Edited by Divine, 01 April 2009 - 02:53 PM.


#42 nowayout

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Posted 01 April 2009 - 03:27 PM

I don't know what Planet andre is from, but I've never seen someone look so young like Andy. ... I live in the UK ...


Ah, that explains it. :)

Edited by andre, 01 April 2009 - 03:28 PM.


#43 nowayout

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Posted 01 April 2009 - 03:50 PM

Haven't confused the two once. Show me even one thirty three year old with skin that looks like Andy's. And yes, I would most certainly feel the same way if this were a female we were talking about.


Compare Barbie Hsu http://farm4.static....fb27ef6.jpg?v=0 and Andy Milonakis http://img2.timeinc....0914/andy_l.jpg and get back to me. Mr Milonakis's skin is obviously full of blemishes and discolorations (age spots), and his facial features are starting to droop (in other words, he is getting jowls like an older man), and he is getting bags under his eyes. In comparison, Ms. Hsu looks phenomenal. Admittedly, she is wearing makeup, but I do not think Mr Milonakis could come close even with makeup.

EDIT: By the way, the picture shown of Ms. Hsu was taken in 2006 and the one shown of Mr. Milonakis in 2005.

Edited by andre, 01 April 2009 - 04:02 PM.


#44 Ben Simon

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Posted 01 April 2009 - 03:54 PM

Haven't confused the two once. Show me even one thirty three year old with skin that looks like Andy's. And yes, I would most certainly feel the same way if this were a female we were talking about.


Okay, I'll do better and show you a 32 y/o with better skin than his. compare Barbie Hsu (32 y/o) http://farm4.static....fb27ef6.jpg?v=0 and Andy Milonakis http://img2.timeinc....0914/andy_l.jpg and get back to me. Mr Milonakis's skin is obviously full of blemishes and discolorations (age spots), and his facial features are starting to droop (in other words, he is getting jowls like an older man), and he is getting bags under his eyes.


I honestly think her skin looks older. She has nice skin to be sure, but the texture is largely what's at issue. Andy's skin looks soft and young. Hers just looks like good skin.

#45 Brafarality

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Posted 01 April 2009 - 03:59 PM

Very impressive.
The extra weight will probably cause system failure at some point rather than this guy passing from sheer old age.
Would he live to 120 otherwise?
Hard to tell.

#46 VidX

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Posted 01 April 2009 - 04:19 PM

It's actualy very speculative to conclude something about his biological age as we have no idea what's his life expectancy at this moment (maybe he has half of what would have a "normal" 30year old, besides his physical appearance.). 

Study needs to be done! Andy, we are comming to get you, don't worry, cages are comfortable these days, and some of the chimps are really entertaining to watch :)

Edited by Divine, 01 April 2009 - 04:21 PM.


#47 TianZi

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Posted 01 April 2009 - 05:26 PM

He doesn't look healthy.

#48 TheFountain

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Posted 01 April 2009 - 08:05 PM

I don't know why you guys keep repeating this as if it were accepted fact. Many 30-year olds have flawless skin.


You are confusing the issue here. We are not talking about blemish free skin, we are talking about a level of collagen and elastin sustainence that is unheard of in 33 year old men. Try as you might, you cannot produce one unbiased source that will tell you, after showing them a picture or video, that he looks anywhere near his chronological age. And if you claim otherwise I will know immediately you are full of it.

Edited by TheFountain, 01 April 2009 - 08:17 PM.


#49 TheFountain

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Posted 01 April 2009 - 08:15 PM

Haven't confused the two once. Show me even one thirty three year old with skin that looks like Andy's. And yes, I would most certainly feel the same way if this were a female we were talking about.


Compare Barbie Hsu http://farm4.static....fb27ef6.jpg?v=0 and Andy Milonakis http://img2.timeinc....0914/andy_l.jpg and get back to me. Mr Milonakis's skin is obviously full of blemishes and discolorations (age spots), and his facial features are starting to droop (in other words, he is getting jowls like an older man), and he is getting bags under his eyes. In comparison, Ms. Hsu looks phenomenal. Admittedly, she is wearing makeup, but I do not think Mr Milonakis could come close even with makeup.

EDIT: By the way, the picture shown of Ms. Hsu was taken in 2006 and the one shown of Mr. Milonakis in 2005.

That woman looks, at best, 25. Andy still looks like a teenager. I have never met a single individual of any age who hasn't confused him with a teenager. And your basis of comparison here is aesthetic not actually how young each person looks. I don't care who you talk to, andy looks about 10 years younger than this woman. And as far as the 'jowels' are concerned. Here are some pictures of andy and some obese teenagers. Tell me the difference (I am sure you will contrive something, because for some reason you hate adolescence and the appearance of such).

http://images.zap2it...33/55433_ba.jpg

http://a.abcnews.com...2_070430_ms.jpg

http://redpants.file...007/12/able.jpg

http://images.rotten...4/210/246_g.jpg

Edited by TheFountain, 01 April 2009 - 08:17 PM.


#50 nowayout

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Posted 01 April 2009 - 09:42 PM

Andy's skin looks soft and young. Hers just looks like good skin.


You're kidding, right?

Attached Files


Edited by andre, 01 April 2009 - 09:45 PM.


#51 Gerald W. Gaston

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Posted 01 April 2009 - 09:54 PM

Andy's skin looks soft and young. Hers just looks like good skin.


You're kidding, right?


If Andy wore the amount of make-up the women has on, he too could likely appear 'blemish' free. As others have pointed out, a youthful appearance can be had without a blemish free complexion, and a blemish free complexion doesn't mean you will be mistaken for a 13yr old.

#52 nowayout

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Posted 01 April 2009 - 10:32 PM

...a blemish free complexion doesn't mean you will be mistaken for a 13yr old.


And being mistaken for a 13 year old is relevant to aging how? (And I mean aging in the degenerative sense, not development.)

Edited by andre, 01 April 2009 - 10:34 PM.


#53 Gerald W. Gaston

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Posted 01 April 2009 - 10:48 PM

...a blemish free complexion doesn't mean you will be mistaken for a 13yr old.


And being mistaken for a 13 year old is relevant to aging how? (And I mean aging in the degenerative sense, not development.)


The topic title is "Andy Milonakis Is 33 but looks 14" ... I am not saying he hasn't aged. I'm saying he is a 33 yr old that looks 13 to me. The model is a very good looking 20-something. Nothing beyond that is implied from my post.

#54 kenj

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Posted 03 April 2009 - 12:31 PM

OH, this is pretty off topic (or maybe not), but he's actually quite entertaining bwahahah:

Andy & The Giant Grapefruit

#55 Skötkonung

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Posted 03 April 2009 - 06:41 PM

Andy's disorder has been identified as a congenital growth hormone deficiency. While theoretically a growth hormone deficiency might lead to a prolonged lifespan, the reality is that these people have increased mortality due almost entirely to other pituitary hormone deficiencies. These people also have an increased relative risk of death in adulthood from cardiovascular causes resulting from altered body composition and dyslipidemia. As was discussed earlier, people with growth hormone deficiencies have delayed onset of puberty and suffer from low production of sex hormones. [1]

To identify Andy as young looking we need to first define what gives the appearance of youth: soft skin, low muscle tone, short stature, higher voice. All of these aesthetic definitions of youth can be explained by his condition. Low production of sex hormones can cause a feminine, softer, appearance and higher voice (see eunuch singers such as Alessandro Moreschi, who was castrated before puberty). Testosterone causes a change in texture to skin. Note, low sex hormones do not correlate directly to infertility.

Attached File  150px_Moreschi_giovane.jpg   5.99KB   33 downloads
(Alessandro Moreschi in his late 20s)

In the presence of a short stature, elevated body fat percentage, low muscle tone, this can be mistaken has youth. Other people with congenital growth hormone disorders such as Charles Sherwood Stratton (see below - although clearly their exact conditions are somewhat varied), have also appeared younger than their actual age, but showed signs of aging as they approached middle age.

Attached File  strattoncharlesbio.jpg   44.32KB   46 downloads
(Middle aged Charles Sherwood Stratton)

I think what is happening here is that we are mistaking Andy's physical traits as evidence of lack of aging, which isn't nessisarily a correct assumption. Take for instance the following male model:

Attached File  DSC_0602.jpg   546.9KB   98 downloads
Attached File  branson1.jpg   22.09KB   35 downloads
(Both of these men are the same age)

The photos in the above article were taken when this man had just turned 20 years old. Arguably, the model would probably pass as someone several years older than his current age due to his heavily masculinized physical features. Is he actually biologically older than his contemporaries? No, I doubt his telomeres are any longer or shorter than an average person of his age. Genetically he was predisposed to develop physical traits we culturally associate with later stages in adult hood. Most of us have probably known a childhood friend who appeared to age much quicker than our other peers. When I was growing up, I had a friend who was shaving at 12 and looked like a full grown man by 15. I appeared quite boyish into my 20s and still get teased about my young looks by older looking coworkers. These types of disparities in the appearance of physical development can be exacerbated by hereditary conditions - leading to a apparant childlike appearance of Andy.

Lets consider Progeria. People with this disease develop diseases of aging very earily and die very early. However, they are not aging. They have normal telomere length (unlike people with Wagners). Progeria is caused by a point mutation in position 1824 Replacing Thymine with Cytosine creating an unusable type of protein called Lamin A. Lamin A is part of the building blocks of the nuclear envelope. Making the assumption they are acutally aging based on their physical traits would be inaccurate.

Attached File  progeria.jpg   6.62KB   22 downloads
(A young child with Progeria)

Finally, lets compare Andy to someone who is actually 14. Below is a picture of me at age 14.

Attached File  me_at_14.jpg   40.77KB   30 downloads
(me age 14)
Attached File  Andy_Milonakis_4.jpg   13.7KB   42 downloads
(andy late early 30s)

Yeah, we look somewhat similar, but if you took away Andy's bodyfat (and the subsequent fullness it provides his face) I think he would actually look a fair bit older. Still young, but not so much in the child like way that has gained him noteriety.

#56 VictorBjoerk

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Posted 03 April 2009 - 10:38 PM

Now, I feel to post some information to make things clear here. There seems to be a lot of misconceptions.

If you suffer from deficiencies in hormones in the pituitary gland(hypopituitarism) and do not go through puberty, yes you will look boyish and young,but you will not become healthier and get an extended lifespan.

Look at this case report for example.


http://jcem.endojour...full/87/12/5430

another interesting thing with this case is that he was only 4'10 tall aged 18 but when he was 43 he had grown to 6'4.

So let's for the umpteenth time conclude that delayed maturation doesn't mean better health and extended lifespan, Aging and maturation in humans isn't connected at all. That's just as obvious as the fact that a girl who gets her first period aged 15 do not accumulate aging damage slower than the early developed girl who get her first period aged 10.

CR delays maturation in rodents but the fact that they develop later is a side effect, not the mechanism that confers longer life.

castration doesn't create prolonged lifespan in humans. If so that would be very well known.

I think Andy Milonakis should be on hormone replacement therapy to prevent osteoporosis due to too low estrogen and to prevent an increased risk of getting CVD and improve general stamina and body compostition.

Edited by VictorBjoerk, 03 April 2009 - 10:53 PM.


#57 TheFountain

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Posted 04 April 2009 - 03:06 AM

Andy's disorder has been identified as a congenital growth hormone deficiency.

has it really been 'identified' as this, or has it been dismissed as this?


To identify Andy as young looking we need to first define what gives the appearance of youth:

No, to identify him as young looking we need only look at him.

soft skin, low muscle tone, short stature, higher voice. All of these aesthetic definitions of youth can be explained by his condition. Low production of sex hormones can cause a feminine, softer, appearance and higher voice (see eunuch singers such as Alessandro Moreschi, who was castrated before puberty). Testosterone causes a change in texture to skin. Note, low sex hormones do not correlate directly to infertility.

hmm, then why is it that scientists are using sex hormone treatment to treat infertility? Hormones, such as kisspeptin are being used to balance hormone levels in infertile people. That shows there is obviously a correlation between sex hormone and sexuality. And the anecdotal fact that andy has had 5 children with several women pretty much cancels out your presumption on this ground.

Lets consider Progeria. People with this disease develop diseases of aging very earily and die very early. However, they are not aging. They have normal telomere length (unlike people with Wagners). Progeria is caused by a point mutation in position 1824 Replacing Thymine with Cytosine creating an unusable type of protein called Lamin A. Lamin A is part of the building blocks of the nuclear envelope. Making the assumption they are acutally aging based on their physical traits would be inaccurate.

Unless we equate aging with a bio-linear phenomenon, as most people tend to do. It could be that systemic metabolic failure due to protein farnesyltransferase contributes to the 'appearance' of aging in these people. Or it could be that there are other, as yet unknown variables we have yet to observe. Either way, something is leading to the 'effects' of aging in these children. Despite whether or not they are aging in the bio-linear sense we often describe. And it is distinctly separate from Andy Milonakis condition.

Finally, lets compare Andy to someone who is actually 14. Below is a picture of me at age 14.

Your point of this was to somehow show that if we 'look deeper' we can actually see a 33 year old man under there somewhere. Hence..

Attached File  Andy_Milonakis_4.jpg   13.7KB   42 downloads
(andy late early 30s)

And andy still looks like a 14 year old kid. But the disillusionment continues below with...

Yeah, we look somewhat similar, but if you took away Andy's bodyfat (and the subsequent fullness it provides his face) I think he would actually look a fair bit older. Still young, but not so much in the child like way that has gained him noteriety.

Yea, he might actually look a whole 16 years of age then! Wow!

#58 DJS

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Posted 04 April 2009 - 04:05 AM

As I was reading Skotkonung's post my girlfriend turned over in bed and looked at my laptop screen. It took a couple of minutes to put the pictures in context for her. :~

#59 alexd

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Posted 04 April 2009 - 05:45 PM

This guy has the haircut and clothing of a teenager. Time for you photo shop pros to alter those aspects. He sure does not look like a 14 year old to me. Also where is the science? Appearance on a computer means little. Hows his respiration, metabolism etc compared to the norm. I have often debated on the 2k year old man (thanks Mel Brooks) spontaneously happening but I do not think this is it. "Nothing happening here folks move along."

Like where is the 60 year old cat, the 12 year old mouse, the planairan that lived a half year..... why just a human. I think the inquiry is valid, but I do nothink this is the grail.

#60 TheFountain

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Posted 04 April 2009 - 11:36 PM

This guy has the haircut and clothing of a teenager. Time for you photo shop pros to alter those aspects. He sure does not look like a 14 year old to me. Also where is the science? Appearance on a computer means little. Hows his respiration, metabolism etc compared to the norm. I have often debated on the 2k year old man (thanks Mel Brooks) spontaneously happening but I do not think this is it. "Nothing happening here folks move along."

Like where is the 60 year old cat, the 12 year old mouse, the planairan that lived a half year..... why just a human. I think the inquiry is valid, but I do nothink this is the grail.


Pure condescension and disillusionment ^^^^^^^




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