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IGF-1 Inhibitors


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#31 hivemind

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Posted 08 December 2011 - 05:35 AM

Vegetarian lifestyle which is known to have lower igf-1 is associated with improved healthspan in men, providing when combined with other factors nearly 10 years added lifespan.


IGF-1 is depended on protein intake. Vegetable protein raises IGF-1 too.

That added lifespan happens only when you compare vegetarians to people who are less interested in their health on average.(the big masses) Nothing to do with vegetarianism.
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#32 steampoweredgod

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Posted 08 December 2011 - 05:41 AM

Vegetarian lifestyle which is known to have lower igf-1 is associated with improved healthspan in men, providing when combined with other factors nearly 10 years added lifespan.


IGF-1 is depended on protein intake. Vegetable protein raises IGF-1 too.

That added lifespan happens only when you compare vegetarians to people who are less interested in their health on average.(the big masses) Nothing to do with vegetarianism.

The study comparing CR society members with vegetarians indicated vegetarian protein consumption is about 10% of diet, lower than CR practitioners and general population, and they have lower igf1.

Given that low igf1 appears to confer vast resistance to cancer in humans, it might explain how someone could be a heavy smoker and reach 100 years without dying of cancer.

Edited by steampoweredgod, 08 December 2011 - 05:42 AM.


#33 steampoweredgod

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Posted 08 December 2011 - 03:34 PM

If green tea does indeed also reduce igf-1, heavy green tea consumption associated with positive benefits, the groups with high green tea could be hypothesized to have lower igf-1.

These groups have also seen benefits in statistical comparison studies.


The following two studies are also suggestive of the benefits of low igf-1

While necessary for proper growth in children, IGF-1 has been linked to tumor growth in adults in a number of studies, including two large trials jointly conducted by Harvard Medical School and Brigham and Women's Hospital: a six-year study of 32,826 nurses, which found that those with the highest levels of IGF-1 had a two-and- a-half times greater risk of colorectal cancer, and a study of 14,916 male physicians, which concluded that men run the same risk. (Wei EK, Ma J, et al. Cancer Epidemiol Biomarkers Prev 2005; Ma J, Pollak MN, J Natl Cancer Inst., 1999)

Earlier data from the study on male physicians also showed that men with the highest levels of IGF-1 had more than four times the risk of prostate cancer than those with the lowest levels. ( Chan JM, Stampfer MJ, et al. Science 1998) And other research involving premenopausal women found that those younger than 50 with high IGF-1 levels had two-and-a-half times the relative risk of breast cancer compared to those with the lowest levels. (Schernhammer ES, Holly JM, et al. Cancer Epidemiol Biomarkers Prev., 2005)


I've heard some doctors say that the lower your igf-1 the better.

Edited by steampoweredgod, 08 December 2011 - 03:35 PM.


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