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List of Herbal MAOI-A's


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8 replies to this topic

#1 enoch1

Posted 07 May 2011 - 04:51 AM


hi All

Just wondering if anyone is familiar with any herbs that are MAOI-A ?

Thanks in advance

#2 enoch1 Re: List of Herbal MAOI-A's

Posted 07 May 2011 - 06:00 AM

Has anyone used the following as a MAOI-A source:

Curcumin (Turmeric)
Coptisine (Goldthread)
Harmala Alkaloids (Syrian Rue, Passion Flower)
Harmine
Harmaline

?

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#3 John Barleycorn Re: List of Herbal MAOI-A's

  • Location:Canberra

Posted 09 May 2011 - 05:35 AM

Syrian Rue


Absolutely vile stuff. Moclobemide is a vastly better option IMHO.

#4 Delta Gamma Re: List of Herbal MAOI-A's

  • Location:asfdgfhgjklj;k

Posted 09 May 2011 - 07:06 AM

I'm more interested in well tolerated selective MAO-B inhibitors as they have the potential to make PEA a poor man's amphetamine while addressing some of amphetamine's inherent toxicity. Without digging out my research laptop it appears that most well known herbal MAOI's are either MAO-A selective or non-selective (such as curcumin). Also, please for the love of whatever you hold holy don't go for something that's known or likely to be a irreversible inhibitor of MAO-A. The last thing anyone wants is to sink their teeth into a block of cheese and have their heart explode.

http://books.google....O-A SAR&f=false

http://pubs.acs.org/....1021/tx010073b
Here's some SAR info so you guys can have a shot at looking at potential compounds and various affinities.

#5 TheRockst4r Re: List of Herbal MAOI-A's

  • Location:NJ

Posted 09 May 2011 - 02:54 PM


Syrian Rue


Absolutely vile stuff. Moclobemide is a vastly better option IMHO.

I concur; however, from my experience smoking syrian rue prevents the nausea and terrible taste.

#6 Cephalon Re: List of Herbal MAOI-A's

  • Location:Cologne

Posted 09 May 2011 - 04:33 PM

@ enoch1:

Did you check the wikipedia entry for mao inhibitors? There is quite a nice list: http://en.wikipedia....idase_inhibitor
I use Curcumin, but not as an MAO-A inhibitor. I can not tell if it works.

I would definately stay away from harmala alkaloids.

You could use Resveratrol and benefit from other effects on health like sirtuin activation.

St. John's Wort is supposed to be a good MAO-A.

#7 Lufega Re: List of Herbal MAOI-A's

  • Location:Miami, Fl.

Posted 09 May 2011 - 04:43 PM

Manganese is a strong MAO inhibitor. Too strong even. Made me feel a little manic at high doses >20 mg.

#8 John Barleycorn Re: List of Herbal MAOI-A's

  • Location:Canberra

Posted 10 May 2011 - 03:40 AM

Manganese is a strong MAO inhibitor. Too strong even. Made me feel a little manic at high doses >20 mg.



That same dosage caused the beginnings of a vasoconstrictive crisis with me. Never again.



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#9 enoch1 Re: List of Herbal MAOI-A's

Posted 10 May 2011 - 04:15 AM

St johns wort was thought to be a MAOI but I hear now days it's function is similar to an SSRI rather then a MAO-A ?. How does Manganese work I've heard it lowers serotonin ?




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