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Modafinil - The Likelihood of SJS

sjs provigil rash modafinil

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31 replies to this topic

#31 wni420

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Posted 15 January 2018 - 09:49 PM

 

Ive done cycles of Modafinils over years...

 

...And it seems I do start to get some rashes in random places

 

So just now, on my Modafinil cycle, I started getting those rashes

 

In the past they seem to have subsided when I took some time off.

 

This time Ill record, SPECIFICALLY how long it takes for the rashes to disappear 

 

 

However, Its a bit surprising to me given the other strong skin aid supplements Im taking, yet Modafinil is still doing its skin damage (Modafinil, I take 200-400mg, 2-3x per week):

High Dose NAC 2-3g per day

High DHA Fish Oil 1.5-2.5g per day

Accutane 80mg per day

 

 

And Ive been very strict with a nutritional protocol that I know is OPTIMAL FOR ME, cant speak for anyone else (gluten-free, dairy free, low-carbs)

 

Those won't help, because Modafinil increases histamine-release - doesn't matter if you remove any obvious allergens - in susceptible people, your histamine-levels will reach such a high level that many things you'd never react to otherwise, will start causing reactions - like the additives in the Modafinil-pills.

 

Anyways, I recommend you try out LEVOcetirizine - not regular Cetirizine (zyrtec, etc) - LEVO. The Levo-enantiomer is the most selective of the two, and won't cross the blood-brain barrier, while the racemic mix will - for some, it cancels the effects of Modafinil to a great extent - for others, regular Cetirizine has no effect on Modafinil's effects. Depends on how much your cognitions responds to histamine, and not DA or NE, I guess.

 

Levocetirizine is the first-line medication when it comes to Urtikaria, which is basically what you're describing - it ought to have some effect.

 

 

Here's a proof of concept:

https://www.reddit.c...mines_bad_idea/

 

 

Thanks for the info brother!

 

Definitely going to give the LEVOcetirizine  a try!


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#32 Mind_Paralysis

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Posted 16 January 2018 - 03:22 PM

 

 

Ive done cycles of Modafinils over years...

 

...And it seems I do start to get some rashes in random places

 

So just now, on my Modafinil cycle, I started getting those rashes

 

In the past they seem to have subsided when I took some time off.

 

This time Ill record, SPECIFICALLY how long it takes for the rashes to disappear 

 

 

However, Its a bit surprising to me given the other strong skin aid supplements Im taking, yet Modafinil is still doing its skin damage (Modafinil, I take 200-400mg, 2-3x per week):

High Dose NAC 2-3g per day

High DHA Fish Oil 1.5-2.5g per day

Accutane 80mg per day

 

 

And Ive been very strict with a nutritional protocol that I know is OPTIMAL FOR ME, cant speak for anyone else (gluten-free, dairy free, low-carbs)

 

Those won't help, because Modafinil increases histamine-release - doesn't matter if you remove any obvious allergens - in susceptible people, your histamine-levels will reach such a high level that many things you'd never react to otherwise, will start causing reactions - like the additives in the Modafinil-pills.

 

Anyways, I recommend you try out LEVOcetirizine - not regular Cetirizine (zyrtec, etc) - LEVO. The Levo-enantiomer is the most selective of the two, and won't cross the blood-brain barrier, while the racemic mix will - for some, it cancels the effects of Modafinil to a great extent - for others, regular Cetirizine has no effect on Modafinil's effects. Depends on how much your cognitions responds to histamine, and not DA or NE, I guess.

 

Levocetirizine is the first-line medication when it comes to Urtikaria, which is basically what you're describing - it ought to have some effect.

 

 

Here's a proof of concept:

https://www.reddit.c...mines_bad_idea/

 

 

Thanks for the info brother!

 

Definitely going to give the LEVOcetirizine  a try!

 

 

No prob's! ^^ Good luck, and good health to you, friend!



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