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addressing peptides bring drugs to mitochondria as well as specific tissues


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#1 OFFLINE   treonsverdery

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Posted 16 July 2012 - 04:15 PM


Addressing peptides http://www.bing.com/...essing peptide" are peptides published as causing things to go to particular places at the body. some listed online carry material through mitochondria as well as other membranes. I think that linking these addressing peptides to little pharmaceutical molecules brings active drugs to particular places at the body providing benefit. while that is pretty obvious consider that if a person takes a lipid soluble drug, it likely concentrates all over the body where there are lipids. Thus a system that brings lipid soluble drugs to aquaeous cytoplasmic environments could bring stronger effect or new effect or more precise effect from a known beneficial drug. From a longevity perspective what might deprenyl or metformin or spermidine do if attached to an addressing peptide that brought them to the cytoplasm

thus I think existing as well as new longevity drugs should be tested with adressing peptides to find better or new effects.

rather weirdly I have not found a reference online where a person attaches an addressing peptide to a less than 400 AMU pharmaceutical molecule. so basically, any little molecule with an addressing peptide is a new drug.

#2 OFFLINE   treonsverdery Re: addressing peptides bring drugs to mitochondria as well as specific tissues

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Posted 16 July 2012 - 04:28 PM

I think it would be wonderful to create a longevity beauty drug with phosphoibuprofen linked to an addressing peptide.  Phosphoibuprofen is a cox-2 inhibitor that cures as well as prevents cancer.  Ibuprofen is published as being around spf 2 or 3  Thus using addressing peptides to bring phosphoibuprofen to the dermis would likely drastically reduce skin cancer as well as reduce photoaging.  Photoaging is published as being about half of visible aging so a drug that prevents cancer while making people look younger is beneficial.  Women as well as girls may particularly like this drug as phosphoibuprofen strongly prevents breast cancer.

translation:  with this pill people can run around nude at the sunshine the vitamin d as well as phosphoibupren noticeably reduces their risk of cancer the concentrated high spf at the dermis also reduces photoaging strongly




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