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Noopept Sexual side effects thread libido thread

noopept sex erection libido

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#1 victortsoi

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Posted 12 September 2012 - 04:23 AM


So its day 3 of noopept and I have no interest in sex or masturbating whatsoever. Maybe a little just to see if I can. Very weird. Also think my facial hair is growing way slower. I dont care that this happens while I am on noopept, I care if there is a long term problem to think about. I'm 24 years old.

#2 Nootropix

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Posted 12 September 2012 - 04:52 AM

Try add zinc rich food to your stack might help .

#3 Crispy Cat

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Posted 12 September 2012 - 06:47 AM

how high is your dose?
on 20mg morning and afternoon i received the exact opposite effect!
the slow facial hair growth and reduced desire are possible signs of lower testosterone but 3 days would really be far too soon to jump to that conclusion

#4 Mr. Pink

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Posted 12 September 2012 - 08:10 AM

started taking it yesterday. i took one dose yesterday and had a very stressful day that ended with some amazing sex with the GF. took 2 doses today. one in the morning and one around 3pm. I went to the gym around 8pm and started getting very horny after doing some squats. Squats usually make me feel dead and utterly kill my libido (i go all out on them).

so there's a datapoint, though 2 days is way too early to tell. i do also take lots of various types of ginsengs, ginko, and lots of vinpocetine. ginseng and ginko definitely boost my libido. i also take a diet pill called mx-ls7 ultra concentrated. it boost my libido, probably due to its mucana content. but I also took creatine today, though not yesterday, which sometimes gives me ED. i also supplement with zinc and magnesium. i'm 30 yrs old.

#5 Geoffrey

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Posted 12 September 2012 - 10:29 AM

I'm in my 40s and absolutely no reduction in libido or "ability" after taking for about five weeks with a ten-day break in the middle. I *wish* I could stop the facial fungus growing so quickly. Noopept doesn't do that for me, unfortunately.

#6 victortsoi

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Posted 12 September 2012 - 04:34 PM

I'm taking 20mg in the morning so far. I think the libido effect hasnt gone away, but has become less "urgent" and changed somehow. Not in a bad way. I also am taking nitro 250 resveratrol which may also factor into this.

#7 Daruman

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Posted 12 September 2012 - 05:55 PM

I have been on 2x20mg/day of noopept, the only other supplement I take is picamilon.

I have only noticed an increase in libido, although I highly doubt it is due to noopept, probably just changing seasons.

The only affect I can notice is that Noopept makes me a bit happier, but it isn't barely noticeable. Mega doses of 100mg do nothing noticeable. I will probably not buy it again.

Edited by Daruman, 12 September 2012 - 05:56 PM.


#8 @now

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Posted 12 September 2012 - 09:32 PM

Mood changes anyone?

#9 greekpsychonaut

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Posted 12 September 2012 - 10:57 PM

started taking it yesterday. i took one dose yesterday and had a very stressful day that ended with some amazing sex with the GF. took 2 doses today. one in the morning and one around 3pm. I went to the gym around 8pm and started getting very horny after doing some squats. Squats usually make me feel dead and utterly kill my libido (i go all out on them).

so there's a datapoint, though 2 days is way too early to tell. i do also take lots of various types of ginsengs, ginko, and lots of vinpocetine. ginseng and ginko definitely boost my libido. i also take a diet pill called mx-ls7 ultra concentrated. it boost my libido, probably due to its mucana content. but I also took creatine today, though not yesterday, which sometimes gives me ED. i also supplement with zinc and magnesium. i'm 30 yrs old.


Creatine will not give you low libido or anything like that.

#10 Mr. Pink

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Posted 13 September 2012 - 04:12 AM

started taking it yesterday. i took one dose yesterday and had a very stressful day that ended with some amazing sex with the GF. took 2 doses today. one in the morning and one around 3pm. I went to the gym around 8pm and started getting very horny after doing some squats. Squats usually make me feel dead and utterly kill my libido (i go all out on them).

so there's a datapoint, though 2 days is way too early to tell. i do also take lots of various types of ginsengs, ginko, and lots of vinpocetine. ginseng and ginko definitely boost my libido. i also take a diet pill called mx-ls7 ultra concentrated. it boost my libido, probably due to its mucana content. but I also took creatine today, though not yesterday, which sometimes gives me ED. i also supplement with zinc and magnesium. i'm 30 yrs old.


Creatine will not give you low libido or anything like that.


who me? i know from my own personal experience. maybe it won't give you and 99.99% of people in studies or elsewhere ED. but I can tell what's going on with my body. granted it only started happening after taking it for years and years without a break. but went away as soon as the creatine was discontinued.

#11 greekpsychonaut

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Posted 14 September 2012 - 12:31 AM

I still don't believe it. I won't be surprised though if I'm totally wrong.

#12 Mr. Pink

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Posted 14 September 2012 - 02:36 AM

I still don't believe it. I won't be surprised though if I'm totally wrong.


i honestly don't blame you

#13 Crispy Cat

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Posted 14 September 2012 - 06:39 AM

at the point that you stopped taking creatine did you also stop going to the gym ?
asking because exercise will increase libido! and leg exercises are reported to affect testosterone levels!

#14 Mr. Pink

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Posted 14 September 2012 - 07:40 AM

at the point that you stopped taking creatine did you also stop going to the gym ?
asking because exercise will increase libido! and leg exercises are reported to affect testosterone levels!


i kept exercising. after quitting creatine for a while i got rid of ED, and and I lost about 1 rep on all my lifts.

my program has always been built around squats, deadlifts, and bench press. i usually do 5-8 reps with as much weight as i can. and try to add a bit every week.

for me, this type of exercise has a clear negative effect on sexual performance. i mean later that day. when i barely walked out of the gym to my car. i have a hard time performing. the next day, all is well. I've tried to figure out why this is. and found some research that says that heavy resistence exercise doesn't boost T. higher reps with less weight does. also, there's some research that says that initially there's a dip in T after heavy lifting. i go all out, and it feels like torture, as it should. i just care about strength. of course after torture, it messes up performance (not talking about libido. just ED the night of the torture).

when i first tried creatine about 8 years ago, i read it helps with energy and atp, etc. i thought it would help performance in the bedroom. i tried it. about an hour after the creatine i couldn't get hard to save my life. i got used to it though, worked around it. till last year. i was making good progress in the gym but couldn't figure out which of my supps was giving me problems. i started eliminating one by one. it was creatine. again. i'm back on it now, by the way, and so far so good.

anyway, i've been working out since i was 12. I'm 31 now. I know my body pretty well. everyone is different. for every study that says one thing, there's a study that says the opposite. fitness and nutrition are full of myths that everyone keeps repeating. there's no teacher like experience.

to make this post slightly on topic here's my experience with noopept so far:

today is Day 3 and I took it 3 times. i've had 3 sexual encounters in the last 3 days, including one this morning. i also had an encounter by myself the other day, if you know what I mean. tonight, i have no urge for sex. it feels like lowered libido :( or i may just be satiated. motivation is high though and for me this is huge!

#15 Pureacetam

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Posted 22 October 2012 - 04:11 AM

This is getting crazy for me! Been taking Noopept on and off (some weeks multiple times a day, others only sporadically) and its definatly working. I become more focused and have a better working memory, etc. But I haven't been able to get an erection for more than a minute, even after discontinuing the Noo for a few days! Any reccomendations on additional supplements/vitamins/etc. that could help this? Anything is appreciated :/

#16 Mr. Pink

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Posted 22 October 2012 - 06:00 AM

how long have you been on it Pureacetam? I've heard to take a month off after a couple months on. I've been on it for over a month now, everyday, 10mg x 3 times a day and haven't noticed problems in libido or performance. i've been taking gingko, artichoke, and a morning stimulant that has a bit of mucana pruriens in it. also, been lifting weights regularly.

#17 Pureacetam

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Posted 22 October 2012 - 06:18 AM

About a month id say, I've been eyeballing the dosages but based on pictures I'd say I'm taking a modest amount. I'm sure exercise would help this, I've been slacking om that. Do any of those three you listed help with this issue? Definatly interested in exploring any options haha.

Edited by Pureacetam, 22 October 2012 - 06:19 AM.


#18 Crispy Cat

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Posted 22 October 2012 - 06:46 AM

thing is if you can get a full erection that would sort of point more to a mental rather than chemical problem ..
one thing could be that the noopept is making you more academically inclined and actually distracting you from the "job at hand"

firstly id get some mg scales you can get cheap ones aprox $20 from ebay/amazon and although not perfectly accurate will be better and more consistent than eyeballing

secondly you could try some of the more common libido boosters
personally i like
vitamin D3
zink + magnesium
(which both have an effect on testosterone)

there are of course plenty of others that searching these forums should bring up :)

#19 Mr. Pink

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Posted 22 October 2012 - 08:14 AM

About a month id say, I've been eyeballing the dosages but based on pictures I'd say I'm taking a modest amount. I'm sure exercise would help this, I've been slacking om that. Do any of those three you listed help with this issue? Definatly interested in exploring any options haha.


those are the 3 that I think help with this issue :). I am taking a bunch of other supps as well, but they are more support for general health. The other year, I was having some issues with ED and I tried a bunch of herbal supplements that are purported to help - tongkat ali, ginseng, eclonia kava, argenine, horny goat weed. those were all helpful, but in the end it was cutting out the micronized creatine i was taking that solved my problem. I am back on creatine now that i took a half a year break.

#20 FDA Approved

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Posted 22 October 2012 - 12:07 PM

Just ordered noopept and I will be quite happy if I also get the decrease in libido on top of the mental benefits.

#21 sapaiderman

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Posted 03 January 2013 - 10:56 AM

Help! From the very first dose of Noopept I could feel a dwindling away of my sex drive and sexual response...
With that initial dose there was a strange feeling in both my brain and groin and my sex drive just died!!! :sad:
I've read a few posts and it seems that some people do suffer from ED after taking Noopept, is this just a temporary thing or does it come back with continued use? I'm only taking 10mg twice a day and this is only my second day of use.
Luckily I have some Cialis to help me whilst I'm trialing Noopept ;)

Edited by sapaiderman, 03 January 2013 - 10:58 AM.


#22 sapaiderman

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Posted 04 January 2013 - 01:59 AM

Help! From the very first dose of Noopept I could feel a dwindling away of my sex drive and sexual response...
With that initial dose there was a strange feeling in both my brain and groin and my sex drive just died!!! :sad:
I've read a few posts and it seems that some people do suffer from ED after taking Noopept, is this just a temporary thing or does it come back with continued use? I'm only taking 10mg twice a day and this is only my second day of use.
Luckily I have some Cialis to help me whilst I'm trialing Noopept ;)


Well, I'm glad to say that the problems down below were just temporary for me and my normal sex drive and sexual response returned within 48hrs. :-D

#23 Manus

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Posted 21 March 2013 - 11:35 PM

Hello everyone,

Just wanted to say i'm so glad others have been reporting their experiences with Noopept and it's effects on their libido. I see i'm not the only one who has also suffered some "less than" favorable side effects from taking Noopept.

Here are my physical stats:
AGE: 42
Height: "5 11"
Weight: 200 lbs.
Build: Extremely Athletic /former Bodybuilder
Exercise: 4-5 times a week

Daily Nootropic Stack (taken 2 times a day)
*Aniracetam (750mg)
*Noopept (20mg)
*Sulbutamine (400mg)
*Choline Bitartate (2grams)
*Omega Fatty Acids (1000mg)
*Focus XT (1 scoop)
*Choline Complex by Naturol (4 scoops)
*Multi Vitamin /Mineral (time released supplement) -1 tablet


Now to be fair, let me first start out by saying "I LOVE nootropics"!!! i've been into numerous ones since the early 1990's and have been using them and getting them from the UK, way before the famous book "Smart Drugs" ever came out.

So in regards to establishing and understanding things like dosages, tolerance levels, self testing and keeping accurate records, I'm on top of that.

What I have noticed however is that, upon the 3rd day of taking 20mg of Noopept (2 times a day) my libido and overall interest in sex has dimished significantly.

Not that reducing the daily preoccupation with sex or getting laid is necessarily a bad thing, but I must say I was quite surprised to experience "NO Interest or desire for sex" at all..!!! Of every nootropic i've ever tried or even nutritional supplement for that matter, this is the first one that has ever caused me to have literally "Zero" interest in sex.

Now what's funny, the upside of this is that when I've seen a beautiful woman and approached her to make casual conversation, it's been quite fun because I've experienced "Zero" anxiety (because it honestly doesn't matter to me if she shoots me down or not)....(or perhaps it's because of Noopept's reported anti-anxiety effects). My mind is seriously not interested in any sexual outcome.....truth be told, it's sort of fun because it's whole new sensation for me. I've found that because of this somewhat "diminished sex drive", my conversations with the opposite sex have much more depth and quality. And believe it or not, I've actually started to meet and go out with way more beautiful women than I ever had before. I guess that's a definite plus for Noopept!!!

Now I will say in the areas of sexual performance it has been amazing!!! My orgasms have been exteremely intense and lasted even longer. It hasn't caused any erectile disfunction in any way.

All of the other reported positive benefits that many countless others have reported about Noopept, I have to agree with. It defintely works and has even seemed to cause my muscular gains from weight training to acclerate a lit bit more. But in the areas of running and maintaing cardiorespiratory fitness, I've noticed an immediate down side. As a recreational runner, I usually clock between 40-60 miles weekly. After taking Noopept, I realized I had to begin taking a day off from my normal running. If it was active in my system, my endurance simply suffered greatly.

Over all, I'd have to say Noopept is definitely a good effective nootropic, but it's possible negeative and long term effects certainly warrant further in-depth study.

#24 Strelok

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Posted 22 March 2013 - 12:01 AM

Over all, I'd have to say Noopept is definitely a good effective nootropic, but it's possible negeative and long term effects certainly warrant further in-depth study.


Manus, how long have you been taking Noopept, and do you cycle it, or have you cycled it/gone through a washout period?

#25 Manus

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Posted 22 March 2013 - 04:12 AM

Well as of today, I've been taking it for 45 days. I take it 5days straight with 2 days off each week.

#26 totalrecomp

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Posted 22 March 2013 - 01:59 PM

I have dosed the following:
T:30mg AM
W: 20mg AM
TH: 30mg AM 20mg PM
F:40mg AM

Nothing but positive results for me. Excellent focus, improved short term recall, energy that has compensated for lack of sleep, improved mood(less depression and easier to control temper), enhanced sense of purpose, mild transient anxiety(this comes and goes even when on nothing) no decrease in desire for sex or ability to perform, improved vision as if my previous vision was old school high definition and on noopept I posses 1080p vision. Enhanced appreciation of music. Enjoyment of reading has increased as has retention and comprehension.

Overall this compound is my favorite so far and supplies almost exactly what I am looking for in a nootropic. I do get the sense that it is something to be respected and breaks are to be taken as to preserve the benefits and avoid possible unforeseen pitfalls.

#27 perplex

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Posted 26 November 2013 - 07:02 PM

I love Noopept. Unfortunately like many I suffered noticable sexual sides while on it. More specifically both sex drive and EQ were considerably reduced. Seeing as I enjoy this noot and its effects so much I'm determined to find out how can I reverse these effects.

Once I stopped my Noopept trial it took me sometime to get my Libido back on track. With the help of several members of our community we discussed several different theories/approaches on how to solve this issue; namely:

(1) Supplement Nitric Oxide drivers - (e.g) Artichoke extract
(2) Supplement on natural testosterone boosters
(3) Supplement on choline

Although some of the above helped treat the problem temporarily what really re-established my Libido to its normal mid-twenties prowess was when I tried (3). However, it was a specific source of choline that helped. I tried eggs and lecithin before to very little effect - it was only once I started supplementing with CDP choline that my sex switch turned back on.

It is well known around the community that CDP Choline provides Uridine which in turn helps regulate dopamine production and increase dopamine receptor densities. I've seen several people mix Mr. Happy's Uridine stack with Noopept and report good results with limited sides. In addition I've seen 'EPIQ noopept complex' already comes with uridine and cdp-choline. All the above seem to point to one conclusion:

Noopept and it's negative sexual side effects are a dopamine related issue which could in turn be mitigated through co-ordinating simultaneous use of dopaminergic normalizing supplements such as citicoline (cdp) and/or Uridine.

I would like your feedback on this

Edited by perplex, 26 November 2013 - 07:03 PM.


#28 mission780

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Posted 12 December 2013 - 04:43 PM

I love Noopept. Unfortunately like many I suffered noticable sexual sides while on it. More specifically both sex drive and EQ were considerably reduced. Seeing as I enjoy this noot and its effects so much I'm determined to find out how can I reverse these effects.

Once I stopped my Noopept trial it took me sometime to get my Libido back on track. With the help of several members of our community we discussed several different theories/approaches on how to solve this issue; namely:

(1) Supplement Nitric Oxide drivers - (e.g) Artichoke extract
(2) Supplement on natural testosterone boosters
(3) Supplement on choline

Although some of the above helped treat the problem temporarily what really re-established my Libido to its normal mid-twenties prowess was when I tried (3). However, it was a specific source of choline that helped. I tried eggs and lecithin before to very little effect - it was only once I started supplementing with CDP choline that my sex switch turned back on.

It is well known around the community that CDP Choline provides Uridine which in turn helps regulate dopamine production and increase dopamine receptor densities. I've seen several people mix Mr. Happy's Uridine stack with Noopept and report good results with limited sides. In addition I've seen 'EPIQ noopept complex' already comes with uridine and cdp-choline. All the above seem to point to one conclusion:

Noopept and it's negative sexual side effects are a dopamine related issue which could in turn be mitigated through co-ordinating simultaneous use of dopaminergic normalizing supplements such as citicoline (cdp) and/or Uridine.

I would like your feedback on this


How much and for how long have you been supplementing with CDP choline to see these positive results?

#29 Crispy Cat

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Posted 12 December 2013 - 07:01 PM

I love Noopept. Unfortunately like many I suffered noticable sexual sides while on it. More specifically both sex drive and EQ were considerably reduced. Seeing as I enjoy this noot and its effects so much I'm determined to find out how can I reverse these effects.

Once I stopped my Noopept trial it took me sometime to get my Libido back on track. With the help of several members of our community we discussed several different theories/approaches on how to solve this issue; namely:

(1) Supplement Nitric Oxide drivers - (e.g) Artichoke extract
(2) Supplement on natural testosterone boosters
(3) Supplement on choline

Although some of the above helped treat the problem temporarily what really re-established my Libido to its normal mid-twenties prowess was when I tried (3). However, it was a specific source of choline that helped. I tried eggs and lecithin before to very little effect - it was only once I started supplementing with CDP choline that my sex switch turned back on.

It is well known around the community that CDP Choline provides Uridine which in turn helps regulate dopamine production and increase dopamine receptor densities. I've seen several people mix Mr. Happy's Uridine stack with Noopept and report good results with limited sides. In addition I've seen 'EPIQ noopept complex' already comes with uridine and cdp-choline. All the above seem to point to one conclusion:

Noopept and it's negative sexual side effects are a dopamine related issue which could in turn be mitigated through co-ordinating simultaneous use of dopaminergic normalizing supplements such as citicoline (cdp) and/or Uridine.

I would like your feedback on this

very interesting.. I have always had positive increase in libido from noopept but i have also nearly always been using 300 to 600 mg of DL Phenylalanine at night which is a dopamine precursor! (also gives vivid dreams and helps me wake up and get up the following morning without hitting snooze!)

#30 perplex

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Posted 14 December 2013 - 06:22 PM

I noticed CDP Choline was only masking the problem, since my issues returned as soon as I dropped It.

I also noted that the problem is further exasperated with the use of some other nootropics such as piracetam.

Therefore, It is my impression that this could be a personal problem of mine, of dopamine depletion.



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