2 replies to this topic

[ClarkSims]

I was going over this paper again, "Baati T, et al., The prolongation of the lifespan of rats by repeated oral administration of C60 fullerene, Biomaterials (2012),
and I was confused by the oxidized glutathione / total glutathione ratio. To my ear
this ratio sounds like it should be

oxidized glutathione / (total glutathione) =
oxidized glutathione / (oxidized glutathione + reduced glutathione)

and therefore should always be less than 1.

In figure 5b, the number is usually greater than one.

http://acumensoftwar....com/gratio.png

Perhaps did they meant to say oxidized glutathione / reduced glutathione ratio?

[niner]

The nomenclature seems a little imprecise... I think what they mean is GSSG / GSH, i.e. the oxidized form over the reduced form.

[ClarkSims]

Thanks for confirming my suspicion.