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[Reformed-Redan]

What research is there on deprenyl and extending humans lifespan. Just because rats benefited from deprenyl doesn't necessarily mean humans will. I'm wondering if you should even start deprenyl if you're under 30 or 40 for example. I don't like messing with my dopamine system. If anything I'd rather have lower dopamine levels than higher. To be on the safe side. What really gets me excited is glutamate. Wonder if anything can boost neural transmission without the excitotoxic effects.

[jadamgo]

There is no research on deprenyl as a longevity enhancing drug in healthy humans of any age.

Since glutamate is the primary excitatory neurotransmitter, literally the backbone of most brain activity, anything which stimulates you will stimulate glutamate. Ritalin, piracetam, oxiracetam, healthy diet, frequent exercise, bright light, positive social interactions, caffeine, healthy sleep patterns... all of it enhances glutamergic activity.

If you are asking for ways to specifically target the glutamate system without involving other systems, there is no such way, because glutamate is involved with everything the brain does. Even things beyond neurons -- glutamate has regulatory effects on (and is sometimes regulated by) glial cells.