What's with the psychologisms? We're dealing with NMDA-potentiation induced chronic headaches not 'painful self-awareness'. Repeat: on-topic please.
As a strictly on-topic matter for the specific purpose you've identified, I don't object to the bulk of what you've said, but this -
MXE is perfectly safe as a low-dose daily NMDA antagonist.
- is where I disagree. You're basing your statement on limited scientific research. This research conflicts with the experience of many regular users who felt fine for a few weeks or months, but I have yet to read a report of anyone taking MXE for longer than a few months without experiencing serious repercussions that were (according to my reading of their reports) less tolerable than what a sufferer from chronic pain would endure as a result of a comparable period of taking opiates.
Opiates have centuries of widespread use, and millions of people are able to take opiates on a daily basis without side effects that outweigh benefits. Are they ideal? of course not. And this is where I agree with you about methoxetamine --- it might be preferable to opiates as a means of handling the glutamate cascade that we've hypothesized to be the cause of suffering for a few sunifiram users. It's not ideal to be taking a dissociative every day, but if it makes life bearable and there aren't better alternatives then go for it. In this specific instance, it's possible that there aren't better alternatives.
Ketamine, according to my research, shows stronger antinociceptive effects, but I presume you chose MXE for legal reasons...?
As for your own case - you just didn't like the slight dissociative effect - your preference, not a hazard.
Somewhat true. The point I was trying (and failing) to make is that I compulsively took it in spite of not enjoying it. This is classic addiction behavior. I'm not triggered to take anything compulsively unless it has some kind of reinforcing quality that compels me. I've had amphetamines that I was able to control better than MXE, for instance. But this is "case study" single-user anecdotal stuff so of course I'm not trying to generalize, just warning that others MAY have similar issues.
Others found they could use low doses without said effect and still others found that these side-effects were tolerable.
True dat. Lots of glowing reports all over the drug forums. Like I said, I've not seen any such reports that extend beyond a few months that don't also include a discussion about addiction, but I'm sure they exist.
If what you're advocating is a reasonably finite course of MXE then please accept my apologies, as I'm mostly addressing the problems of using that can obtain from longer-term usage. Perhaps the results people seek could be realized within a matter of weeks, not months, in which case I'm in full agreement with you!