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Antibiotics could cure 40% of chronic back pain patients

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#31 niner

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Posted 23 September 2014 - 09:47 PM

 

If I was you, I would show it to a doctor.  What color is it?  Does it have irregular edges, or smooth edges?

 

 

Are you thinking tick bite?

 

No, it's likely to be nothing, but I'd like to rule out melanoma.



#32 AmyHazy

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Posted 24 September 2014 - 05:50 AM

OH MY GOD IT LOOKS LIKE A BED BUG BITE. I done told my mom I had bed bugs in my last bed. Im boust to cry. fr. Im on an air mattress. this cant happen. 



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#33 AmyHazy

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Posted 24 September 2014 - 06:37 AM

Im just going to tell my mom to take me to the clinic or something. I need this checked. It has been weeks. it looks like chicken pox, but how can there be one? makes no sense. but its bigger than that picture. Its the closest I can get to. & it hurts to the touch. 

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Edited by AmyHazy, 24 September 2014 - 06:47 AM.


#34 niner

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Posted 24 September 2014 - 01:36 PM

Well, the good news is that it's not melanoma.  I see three lesions, not one. 



#35 1kgcoffee

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Posted 28 September 2014 - 03:01 AM

The link speaks about Propionibacterium Acnes being the main but not the only bacteria responsible for lower back pain in 40% of cases AmyHazy. I assume the other bacteria are similar/related, but that just an assumption and it would be nice to know what the other bacteria were as only antibiotics effective against these would work.
http://www.theguardi...k-pain-patients
 
 
Thx for the anecdotal report 1kgcofee. Nitazoxanide sounds very interesting as interfering with anaerobic respiration may also be effective against cancers?
Is Nitazoxanide effective against Propionibacterium Acnes and company?

 

You mean like DCA? Probably not, its only seems to be effective against protozoa and bacteria, human mitochondria do not have the same pyruvate reducing enzyme. But according to this study it does stimulate autophagy and inhibits mtor, so there may be some effect on tumor suppressor genes from its primary metabolite.

 

It may be more of a cancer preventative, if it is effective against cancer generating pathogens which propionibacterium are a part.

 

edit to add: Is it effective against acne? I've heard of tetracycline being used but never Nitazoxanide. It may be too strong for something not life threatening.


Edited by 1kgcoffee, 28 September 2014 - 03:08 AM.


#36 Logic

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Posted 29 September 2014 - 07:20 PM

You mean like DCA? Probably not, its only seems to be effective against protozoa and bacteria, human mitochondria do not have the same pyruvate reducing enzyme. But according to this study it does stimulate autophagy and inhibits mtor, so there may be some effect on tumor suppressor genes from its primary metabolite.
 
It may be more of a cancer preventative, if it is effective against cancer generating pathogens which propionibacterium are a part.
 
edit to add: Is it effective against acne? I've heard of tetracycline being used but never Nitazoxanide. It may be too strong for something not life threatening.


Thx. I'll look into this more.

#37 Peder Holdgaard Pedersen

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Posted 04 October 2014 - 03:46 PM

Don't believe your theory, Logic, either about acne or back problems. If bacteria caused acne, we'd see a lot more of it in places where people had trouble keeping clean, like Africa or the slums of India. Instead their skin is clear. We see more acne in more developed countries.

Acne affecting pubescent boys primarily is a hint that dermal pathogens could very well be the cause. When their bodies are growing they become stressed, either via psychological stress or physiological stress. Both of these cause an a diversion of metabolic energy from the peripheral immune system to other places. Our bodies dont care about superficial infections when they need to survive or grow.

I believe the visible acne is not the primary pathogen - the follicles are manipulated by the anaerobes to produce more sebum, so that the well-known acne postules and pimples appear. It then stimulates the release of histamine and other things that will make us scratch these postules, possibly even causing a localized antinociceptive effect. When we scratch the pimples, and our immune system murders the agents present in the sebum, scar tissue is left behind - an awesome environment for collagen eating anaerobes. We might even spread them across our skin when we are scratching and popping the acne. It gets on our fingers and into our mouthes and noses, which is a really great place with little oxygen. Ever had a weird pimple like thing on the tongue or inside the nose? Congratulations, you had might have had a confused anaerobic colony who thought they were on the dermis, and tried to increase sebum production.

Some bacteria, for example Burkholderia Pseudomallei, can detect the presence of insulin and react to it. Maybe that is why eating fat and sugar causes acne, even in places the food never got near? The bacteria sense the insulin and react to it. Some of them can even secrete their own insulin or other hormones, tricking our bodies into creating a good environment. Our diet might be a requirement for these bacteria to thrive. The emerging cultural taboo on sugar might be a collective immunoresponse to this organism. This might be why some pimples have white clean, uninfected sebum - they are the result of endocrine manipulation, but the accomplice bacteria wasn't there to alert the immune system. 

Maybe acne is caused by a pathogen which uses it as a method to gain entry to our bloodstreams, adipose tissue, nasal and oral cavities? Maybe people who have compulsions about picking their skin are infected with a manipulative pathogen? Toxoplasmosis has been proven to manipulate mice into getting eaten by cats. Why shouldn't a human targeted pathogen be capable of manipulating us into absorbing it, and maybe even spreading it? Maybe it gives us hay fever, so we sneeze and spread it to other people - like how the common cold tries to manipulate us into spreading it.


Edited by Peder Holdgaard Pedersen, 04 October 2014 - 03:48 PM.

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#38 Darryl

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Posted 04 October 2014 - 06:06 PM

I don't doubt that chronic infection could cause increased inflammatory responses. Biologics like like the TNFα receptor antagonist etanercept (Embrel) block some of this inflammation.

 

But another theory about lower back pain is rather interesting: poor lumbar artery blood flow to the intravertebral disks:

 

Kauppila, L. I. (1997). Prevalence of stenotic changes in arteries supplying the lumbar spine. A postmortem angiographic study on 140 subjectsAnnals of the rheumatic diseases56(10), 591-595.

Kauppila, L. I. (2009). Atherosclerosis and disc degeneration/low-back pain–a systematic reviewEuropean Journal of Vascular and Endovascular Surgery,37(6), 661-670.

 

Summarising the review:

  • Post-mortem studies showed an association between aortic atherosclerosis and degenerative disc disease. 
  • Post-mortem studies showed a strong association between occluded lumbar arteries and a life-time of low back pain. 
  • Clinical studies showed that aortic calcification was associated with low back pain. 
  • Clinical studies showed that stenosis of lumbar arteries was associated with both degenerative disc disease and low back pain. 
  • Epidemiological studies showed that smoking and high serum cholesterol levels were the most consistent associations with degenerative disc disease and LBP. 
  • Cohort large studies showed clear associations between elderly people with cardiovascular risk factors and low back pain.

There's also the association with obesity, which is now considered a risk factor for all inflammatory diseases.

 

Samartzis, D., Karppinen, J., Cheung, J. P. Y., & Lotz, J. (2013). Disk Degeneration and Low Back Pain: Are They Fat-Related Conditions?Global spine journal3(3), 133.

 

Some of you unfairly dismissed the comment by Luminosity above. Lower back pain is a first world health issue because atherosclerosis and obesity are first world health issues.

 

I'm extremely dubious coconut oil would be helpful at all. 


Edited by Darryl, 04 October 2014 - 06:35 PM.

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#39 Luminosity

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Posted 07 October 2014 - 04:50 AM

Or the bacteria could be opportunistic, feeding on the waste material.  



#40 Logic

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Posted 07 October 2014 - 05:45 PM

I'm extremely dubious coconut oil would be helpful at all.


ITs that just an 'If it sounds to good to be true it probably is' knee jerk reaction or have you actuaully read and thought about the evidence provided?

The MCTs in EVCO consist of 3 medium chain acids (Lauric and other acids wth similar effects) all bonded to glycerine.
If 2 of the acids are metabolised off of the glycerine; one third of the MCT acids imbibed remain as Monolaurin/carpin etc.
If all 3 acids are metabolised off of the glycerine; it means that Monolaurin is just a lucrative means of selling Lauric Acid and that all the studies on it are of equal relevance to EVCO.

I suggest trying EVCO for different bacterial and viral infections rather than waiting for a study to appear on something that has no financial incentive to do so. I have.

Edited by Logic, 07 October 2014 - 05:49 PM.


#41 AmyHazy

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Posted 08 October 2014 - 06:58 AM

This may disturb you but It was a pimple that had to be popped many times. lol. My back hurts still. I went to the doctor yesterday, she only gave me paperwork about chronic pain and anxiety. I think I may qualify for chronic pain because I do get migraines and neck pain as well. I just hate bacteria... I wash my skin with softsoap antibacterial and my eczema looks so much better especially in these cold temperatures. I don't trust lotion with oils, I rather choose baby lotion with free parabens and what not. And Darrl to your artery explaination, times I go to the doctor my pulse atleast over 90 then back to 60ish. My heart shouldn't be working harder than it should be at random times, when I'm sitting perfectly fine. Now I have pain along with it. I'll mention it to my doctor next visit, which is soon. 



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#42 Logic

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Posted 08 October 2014 - 12:05 PM

This may disturb you but It was a pimple that had to be popped many times. lol. My back hurts still. I went to the doctor yesterday, she only gave me paperwork about chronic pain and anxiety. I think I may qualify for chronic pain because I do get migraines and neck pain as well. I just hate bacteria... I wash my skin with softsoap antibacterial and my eczema looks so much better especially in these cold temperatures. I don't trust lotion with oils, I rather choose baby lotion with free parabens and what not. And Darrl to your artery explaination, times I go to the doctor my pulse atleast over 90 then back to 60ish. My heart shouldn't be working harder than it should be at random times, when I'm sitting perfectly fine. Now I have pain along with it. I'll mention it to my doctor next visit, which is soon. 

 

:)

I thought it was a pimple/s from the pic.

From the sound of it (back pain, headaches, eczema) you may have an unhealthy gut:

 

There are 10X as many bacteria in your gut than cells in your body.

Once food is past the stomach its absorbed by these bacteria, metabolised and the waste excreted. 

ie: each cell in your body (you) is living on bacteria shit from 10 bacteria! :)

This being the case; its a good idea to make damn sure that you approve of the bacteria! (and their excrement)

 

It sounds like you may have too many candida. (yeast infections are a good indicator of this)

Do a site search for prebiotics probiotics, as well as Candida.

FOS, Inulin, RS should help.  Also the above mentioned-to-death EVCO kills off Candida and other nasty gut bacteria and is slimming.   Also try it topically. (on your skin)  Its proven to work.

Parabens are associated with breast cancer..?

 

Niner will probably recommend C60oo for the Eczema. :)

I think you may be a little young to start using it though and don't know that you would want to halve your rate of aging!  :-D

 


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