• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

Noopept product insert...translation improvement from Russian

noopept nootropic russia

  • Please log in to reply
3 replies to this topic

#1 Gr888Scott

  • Guest
  • 15 posts
  • 12
  • Location:Western North America
  • NO

Posted 18 August 2013 - 06:18 PM


I was reading this widely available drug insert for Noopept and saw so many aggravating mistranslations/no translations.. well I painstakingly "fixed" the errors.Well,it's not perfect, but easier to read and understand.

I will add more and tune-up the various translation errors as I collect them.


So here:

Usage and Instructions (translated from Russian), and improved by Gr888Scott

On medication:

Noopept ® helps to restore memory and cognitive functions, disturbed as a result of brain injury, ischemia, hypoxia, the effects of alcohol and other toxic substances.

Noopept ® is nootropic drug peptide structure. Noopept's uniqueness lies in the fact that in the body, it forms an active metabolite, with identical endogenous dipeptide nootropic activity that is physiologically safe for humans. Noopept possesses neuroprotective properties - protects brain cells from exposure to damaging factors.

The therapeutic effect of Noopept is evident within 5-7 days of treatment, in the form of anti anxiety and tonic effects. At 7-14 days of therapy, there is a vegetative vascular normalizing effect, normalization of sleep. From 14-20 days of therapy revealed a positive effect on cognitive function of the drug, the parameters of attention and memory.

For its effectiveness Noopept ® PIRACETAM exceeds that found in clinical studies, patients with vascular cognitive disorders and post traumatic genesis.
According to clinical studies, the risk of side effects while taking Noopept are almost twice lower than that of Piracetam, suggesting the safety of the drug.

® Noopept is not cumulative in the body, does not cause drug dependence with the cessation of the drug.
Noopept ® does cause injury to internal organs, does not lead to changes in hematological and biochemical parameters, is not immuno-toxic, teratogenic effects, showed no mutagenic properties.

Noopept ® released in pharmacies without a prescription.

2) Instructions for Use:

Registration Number: LS-001577 dated 12.05.2006

Commercial product name: Noopept ®

Rational Chemical name: ethyl ether N-phenylacetyl-L-¬ proglycine

Drug form: tablets.

Composition
Each tablet contains:
Active substance: noopept ® - 10 mg.
Excipients: microcrystalline cellulose, lactose (milk sugar), potato starch, povidon, magnesium stearate.

Description
Tablets are white, with beveled ploskotsilindricheskie.
Pharmacotherapy group: nootropnoe tool. ID ATH: [N 06 BX].

Pharmacological Effects
Noopept ® is nootropic drug with nootropic and neuroprotective properties. Improves learning ability, memory, working on all phases of processing: the primary information processing, consolidation, retrieval. Prevents the development of amnesia caused by electroshock, a blockade of central cholinergic structures glutamatergic receptor systems ironic phase of sleep deprivation.
Neuroprotective (protective) effect Noopepta ® appears to improve the stability of brain tissue to the damaging effects (trauma, hypoxia, Electro, toxic) and alleviating the degree of damage to brain neurons. The drug reduces the amount of focus on thrombotic models of stroke and prevents the loss of neurons in tissue culture cortex and cerebellum, expose neurotoxic concentrations glutamate, free radical oxygen.
Noopept ® has antioxidant effects, antagonistic effects on the effects of excess calcium, improves the rheological properties of blood, with antiplatelet, fibrinolytic, anticoagulant properties.
Nootropic effect of the drug is associated with the formation of cycloprolylglycine, similar to the structure of an endogenous cyclic dipeptide having anti-amnesiatic activity, as well as to the availability choline's positive action.
Noopept ® increases the amplitude of the trans-callosal response, making associations between the cerebral hemispheres at the level of these cortical structures more possible.
Noopept ® helps to restore memory and other cognitive functions, disturbed by the damaging effects – brain injury, local and global ischemia, prenatal damage (alcohol, hypoxia).
Therapeutic effect of the drug in patients with organic disorders of central nervous system manifests itself, beginning with 5-7 days of treatment. Initially implemented in the spectrum of activity Noopept ® has anyxiolytic and easy stimulatory effects, manifested in the reduction or disappearance of anxiety, increased irritability, affective liability, sleep disturbance. After 14-20 days of treatment revealed the positive impact of the drug on cognitive function, the parameters of attention and memory.
Noopept ® has a vegetative normalizing effect which helps to reduce headaches, and orthostatic tachycardial episodes.
® Noopept is not cumulative in the body, does not cause drug dependence with the cessationof the drug .
Noopept ® does not cause injury to internal organs, does not lead to changes in haematological and biochemical parameters, has no immuno-toxic, teratogenic effects, and showed no mutagenic properties.

Pharmacokinetics
Noopept ®, is absorbed into the gastrointestinal tract, in the unaltered system enters the bloodstream, cross the blood-brain barrier determined in the brain in high concentrations than in blood. Time to achieve maximum concentration in an average of 15 minutes. The half of the blood plasma – 0.38 h. The drug is partially preserved unchanged, partly metabolized to form phenylacetic acid and phenylacetylproline cycloprolylglycine. It has a high relative bioavailability (99.7%).

Indications for use
Memory, attention and other cognitive functions, and emotionally labile disorder, including those in patients with advanced age, with
• consequences of cranio-cerebral trauma
• post traumatic stress syndrome,
• cerebral vascular insufficiency (encephalopathy of different genesis)
• aesthenic disorders,
• other states to reduce the signs of intellectual productivity

Contraindications
Pregnancy, lactation period. Age 18 years. Individual intolerance drug. Expressed violations liver and kidneys.

Dosing and Administration
Noopept ® is used inside, after the meal. Treatment begins with application of the drug at a dose of 20 mg, 10 mg distributed in two steps during the day (morning and afternoon). With the lack of effective therapies, and with good portability Noopept ® drug dose increase to 30 mg (see «Cautions»), distributed to 10 mg for three reception during the day. Do not take the drug later than 18 hours. Running a course of treatment is 1.5 – 3 months. Repeat treatment if necessary, can be carried out after 1 month.

Adverse effects
Possible allergic reactions. In patients with severe arterial hypertension (Stage 3), a side effect of taking the medication may be a rise of blood pressure.

Overdosage
Specific manifestations of overdose has not been determined.

Interaction with other drugs
It is unknown how Noopept ® interacts with alcohol, hypnotic and hypotensive drugs and drugs with psychostimulant action.

Cautions
If necessary, increase the dose (30 mg / day), with long-term use, and while the use of other drugs, the appearance of adverse reactions or deterioration of the state should call a doctor.

Composition
According to 25 tablets in contoured blister pack of PVC film and aluminum foil printed varnished.
At 30 or 50 tablets in the banks have polymer with controlled opening.
Bank One or 2 contour blister packaging along with instructions for use in the stack of cardboard.

Storage conditions
List B. In dry, protected from light, at a temperature no higher than 25 0С.
Keep out of the reach of children.

Shelf life
2 years. Do not use a later date on the package.

Terms of leave from pharmacies
Without prescription.


#2 unregistered_user

  • Guest
  • 721 posts
  • 169
  • Location:Washington DC

Posted 19 August 2013 - 04:34 AM

I'd fix this:

® Noopept is not cumulative in the body, does not cause drug dependence with the cessation of the drug.
Noopept ® does cause injury to internal organs, does not lead to changes in hematological and biochemical parameters, is not immuno-toxic, teratogenic effects, showed no mutagenic properties.



sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#3 Gr888Scott

  • Topic Starter
  • Guest
  • 15 posts
  • 12
  • Location:Western North America
  • NO

Posted 20 August 2013 - 03:29 PM

I'd fix this:

® Noopept is not cumulative in the body, does not cause drug dependence with the cessation of the drug.
Noopept ® does cause injury to internal organs, does not lead to changes in hematological and biochemical parameters, is not immuno-toxic, teratogenic effects, showed no mutagenic properties.


Good catch, man :)


Noopept ® does NOT cause injury to internal organs

For some reason I can't get in to edit my original post :|?

Maybe a mod could...

sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#4 Strelok

  • Guest
  • 370 posts
  • 41
  • Location:USA

Posted 21 August 2013 - 01:15 AM

Shouldn't it say that it IS cummulative in the body, i.e. it does bioaccumlate?




0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users