What piracetam dose are you nervous about?
4.8-9.6 g/day. Point is, as with nifedipine, I'd like to avoid (or minimize) intake of xenobiotic substances. I *do* use piracetam (800-1,600 mg/day), and I'd actually previously tried 4.8 g/day but after about two weeks, I'd noticed no improvement at all with respect to Raynaud's.
Let me know if you want me to append this thread to the earlier one.
Yeah, I'd seen that article...if it's helpful to append it (for a focused, concatenated thread on the topic), by all means.
I too, suffer from Raynaud's. Or at least when I am not on an SSRI. When I am on an SSRI (zoloft or prozac) my symptoms nearly completely vanish, even in freezing weather.
Hmmm...FWIW, signs of Ranaud's didn't manifest for me until my late 20's, shortly after I'd gone through ~two years of zoloft. Ironically, much of the rest of my life had been spent with the opposite problem; constantly hot, sweaty palms. When the current problem started, my hands were so scathingly dry and cold (corpse-like) that my hands and fingertips were badly ulcerated...this is still the case to a small extant (you can notice a minor ulceration on my thumb in the photo above). Of course, this adds another problem when I'm touching public door handles, light switches, bathroom faucets, during the day.
Are you on an SSRI right now? I'd been prescribed zoloft to treat severe, life-long depression, suicidal ideation etc. (again, little more than legal drug dealers) Without going into personal detail, my experience on zoloft was pretty....bad. These are no longer an option for me anyway.
Too many other unknowns and nasty seemingly permanent side-effects, not to mention withdrawal.
I've been there, brother.
I haven't tried piracetam but the idea has been with me for some time.
I'm a full-time student, and I can certainly attest to its nootropic effects. Sure, some may see it as a "boring, basic" option, but I think its safety and efficacy vindicates its use, even if its not as potent as other nootropics.
cannabis (
signifcantly helps, and the symptom relief lasts for multiple weeks!)l-arginine (increases nitric oxide and is a vasodilator)Interesting...I wonder about L-Lysine...
beta blockers (epinephrine is heavily implemented in raynauds. Those who have it have lowered levels of epinephrine and dopamine, and proportionately high levels of norepinephrine http://www.ncbi.nlm..../pubmed/3425974Thanks, I'll bring this up with my GP.
alcohol improves circulation but makes m hands bright red
Same here! I'd consumed red wine nightly for a few years, and the relief was remarkable. Indeed, I'd looked forward to it more for that reason than any other. Unfortunately, my liver enzymes have been through the roof for years (I initially incorrectly attributed this to supplement use), and I recently found out via http://snpedia.com/i...php/Promethease that my liver does not process alcohol efficiently and is more susceptible to its toxicity (the same for even healthy fats, unfortunately). Since abstaining from red wine and olive oil, I've found that my plaque psoriasis has markedly improved... But that means that I can no longer seek relief from Raynaud's the way I used to...
CaffeineThis is a tough one. I've tried to cut it out of my routine, but the brain fog hurts my academic performance, not to mention that cutting out caffeine sure as hell doesn't help the depression. It's a Catch-22...
But, going off the finding that there is a high norepinephrine:dopamine/epinephrine ratio in Raynauds sufferers, maybe there is a way to level the three catecholamines out to normal ratios? This is a possible topic for researching more in depth.Thanks for the lead, I'm going to look into this.Another thing that helps greatly is 'physical therapy', that is to say do lots of cardio! And, do exercises for the muscles in your arms, like those hand grips guitarists use. This will allow blood to circulate more efficiently.
I'm a 5K runner and habitual exerciser...but it doesn't make a difference for me (ironically, I didn't have Raynaud's when I was 30 pounds heavier and subsisting on junk food).
Thanks for sharing, it's such a strange, idiosyncratic phenomenon (like psoriasis), it seems there must be some common thread uniting the sufferers...
Edited by Taurus Londoño, 15 February 2014 - 03:08 PM.