Hello,
as much as i understand, for treating anxiety i should avoid supplements, that have GABAergic actions.
So i read here http://www.longecity...ly-effectively/, L-Theanine is not doing it, but on examine.com i found this: http://examine.com/s...ine/#summary4-3
http://www.ncbi.nlm..../pubmed/4397636
"Injections of theanine (30µM/kg only; 15µM/kg being ineffective and all doses higher than 30µM/kg being ineffective) have been found to increase cerebral concentrations of GABA by 19.8% following"
I mean, this seams like a big increase of GABA, wouldnt this lead to tolerance by down regulation of the receptors?
So now i am confused, is it ok to take supplements, that increase the GABA concentrations without beeing anything like an GABA agonist or reuptake inhibitor?
Thanks for answers,
Zuckerwasser
Edited by Zuckerwasser, 19 March 2014 - 09:36 AM.