7 replies to this topic

[YOLF]

Haemophilus influenzae

It wasn't until 1990 that the US started vaccinating against Haemophilus influenzae, so there may be quite a few people on here that haven't received the vaccine. It causes more serious disease in infants and toddlers, but can cause opportunistic infections in anyone which can complicate other conditions and harm their eventual prognosis. This one should be available through your doctor or a hospital network.

 

Serratia marcescens

The vaccine for this one still isn't available in the US, but was tested around 2002 in China with a 97% efficacy for immunogenesis. Also an opportunistic infection which has become common as a soil microbe due to its use during the cold war. Serratia can cause alot of problems including making cancer more virulent, conditions which can harm the urinary tract (esp the kidney), and a range of other complications. I'm trying to organize a group buy for this one and have made posts about it around the forum. You can get more info on it here:

http://www.longecity...vaccine-for-le/

 

I'd like to discuss what role vaccinations play in RLE. Obviously as we get older we become more susceptible to these organisms and they hasten our death and disability. While some are antivaxers, I consider myself a maxvaxer. The more we vaccinate against pathogens, the more likely we are to get more diseases as the change in our microbiomes can lead to more and more opportunistic infections. Therefore, all opportunistic infections must be treated as common pathogens until we can re-engineer our microbiomes. The eventual result may be that we need to engineer safe organisms to produce micronutrients that we rely on.

 

Opinions?

Edited by cryonicsculture, 12 April 2014 - 09:09 PM.

[rwac]

This kinda confuses me a bit. You say that vaccinations lead to more opportunistic infections, but then claim the solution is more vaccinations?

Doesn't that increase the risk of *other* opportunistic infections?

 

Wouldn't you expect diminishing returns from each successive vaccination?

Shouldn't the focus be on vaccinating against real threats?

Edited by rwac, 12 April 2014 - 02:20 PM.

[The Immortalist]

This kinda confuses me a bit. You say that vaccinations lead to more opportunistic infections, but then claim the solution is more vaccinations?

Doesn't that increase the risk of *other* opportunistic infections?

 

Wouldn't you expect diminishing returns from each successive vaccination?

Shouldn't the focus be on vaccinating against real threats?

 

Perhaps he means immunize against opportunistic infections that cause the most harm and forget about less harmful ones.

[YOLF]

Well I don't know about diminishing returns. We can always revaccinate if we need more immunity to something because immunity was lost to other vaccines. 

 

But the idea is more to consider opportunistic threats as real threats (since we're apparently making them that way) and preventing them as we move forward rather than ignoring them. A smaller microbiome will be easier to manage, and we can always take the least harmful of them and add more beneficial genetics to them. For instance, if we found that l. acidiphilus was harmful for us, but we need it's capacity to produce methylcobalamin, we can just add the required genetics to a safer microbe and inoculate with it. In this way, we'd be moving to a more advanced microbiome whose goal is to keep us healthy.

 

 

[rwac]

My point is that in the process of attempting to vaccinate against all known threats, aren't we reducing immunity to unknown threats?

[YOLF]

The question is, are we at any given time more susceptible to an incidence of uncontrolled pathogen than we were prior? With each successive vaccine the pool of potential pathogens is decreased and so is the risk. So let's get there quick.

Edited by cryonicsculture, 13 April 2014 - 07:10 AM.

[rwac]

I fear the list of "potentially pathogenic" bacteria is near infinite. Do we have reason to believe otherwise?

 

The worst case scenario is that any bacteria turns pathogenic if the immune system is weak.

[YOLF]

Well there are about 600 microbes that are known to inhabit us. About 200 of them known to cause disease under the right conditions. Not necessarily near infinite. there are a limited number of organisms which will find us tolerable to live in. 

 

The rest don't live on/in us b/c we don't present the right habitat.

 

I eventually see us vaccinating for everything and then greenlighting beneficial microflora gmo versions of them.