• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

Noopept less effective in those who do CR?

noopept

  • Please log in to reply
1 reply to this topic

#1 InquilineKea

  • Guest
  • 773 posts
  • 89
  • Location:Redmond,WA (aka Simfish)

Posted 22 April 2014 - 04:39 PM


Just wondering. CR tends to suppress protein synthesis (due to mTOR inhibition), as does methionine restriction.

 

But Noopept increases BDNF/NGF, which help increase protein synthesis.

Does CR inhibit Noopept's beneficial effects?



#2 Jim Morrison

  • Guest
  • 70 posts
  • 5
  • Location:Switzerland

Posted 22 April 2014 - 08:50 PM

I would say on the opposite. Reduced nutrient (aminoacid) induced background activity of mTORC1 should sensitize the dentritic compartment to local activation by bdnf.



sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).




Also tagged with one or more of these keywords: noopept

1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users