23 replies to this topic

[nameless]

Just wondering what is considered an optimal B12 level? Around 600+?

I just got some bloodwork back and see I am around 300ish, which is a tad low. Doc recommended 100mcg/daily. Sublingual matter in regard to absorption?

I'm a bit curious why my B12 has been sinking the past 2 years, although I guess it could be due to possibly eating slightly less meat.

Also strangely my D3 levels have gone up to around 55, while most of the time it was around 30-35ish. That is on 2K D3 daily, which is the same dosage I've taken for a while now. Normally I'd wonder if my doc accidentally tested 1,25 instead of 25-D, but this was an endo, so expect (or at least hopes) he knows what he is doing.

Used sunrise labs this time instead of labcorp, so there could be some variation. I didn't expect that much variation though.

[mrnootropic]

I simply reccomend this :

 

Jarrow formulas B-Right.. http://www.jarrow.co...duct/57/B-Right

1 Capsule Of This A Day and you will be fine. It contains all of the most potent and superior forms of B vitamins as well as Methylcobalamin aka Vitamin B12, Folate, P5P. So it will help correct Vitamin B / Folate deficiencies.

http://www.jarrow.co...facts_B_lrg.jpg

 

I recommend this B-Right to everyone, because its changed my waking life, i feel so much better, mainly because of the Vitamin b12 and Folate content. I feel so much healthier, i also take a stack of supplements , but B-Right was one of the first to help & give me any noticable changes and help with B12 Deficiency. 

 

Dont buy any other as its not worth it, unless you get Jarrows Sublingual B12 Lozenges.

Definately do not take Cyanocobalamin (Cyanide+Cobalamin). Make sure its Methylcobalamin, as this is the active form of B12. So just get Jarrow Formulas B-Right, its cheap and it works.

 

 

Edited by Mr.Nootropic, 03 June 2014 - 06:12 PM.

[nameless]

Thanks for the reply.

I'm not a big fan of megadosing some of the Bs, especially if I have no evidence I am deficient in them (B12 being excluded). I've had my folate levels tested in the past, and I have plenty.

And yep, I plan to look for Methylcobalamin. It's just that everyone seems to go with these super megadoses of the stuff.

[mrnootropic]

Thanks for the reply.

I'm not a big fan of megadosing some of the Bs, especially if I have no evidence I am deficient in them (B12 being excluded). I've had my folate levels tested in the past, and I have plenty.

And yep, I plan to look for Methylcobalamin. It's just that everyone seems to go with these super megadoses of the stuff.

 

Ok good

 

I never said megadose lol. I said take 1 capsule a day and you will be fine. 1 Capsule a day Is not Megadosing.

The main reason im telling you to get B-Right is because Jarrow's B12 has proven & tested to Elevate B-Vitamin Levels, whilst other brands failed to do so.

 

We have tested various other forms and brands but Jarrow Formulas B-Right & Enzymatic Therapy B12 & Country Life Vitamin B12 Sublingual came out on top. And if you dont get Jarrow Formulas or the other 2 brands, then i cant guarantee you any benefit or results. Its up to you. 

 

Enzymatic Therapy B12 is a good source & Country Life Vitamin B12 Sublingual is also a good source.

 

You simply dont just buy a b12 pill and pop it. Its just not that simple, alot of brands and forms dont do anything regarding  raising B12 levels and are useless.And some forms of B12 are potentially toxic. You will forever have problems with B12 Deficiency if you dont listen. 

 

Sublingual Vitamin B12 is also the best way to take B12, But the B-Right provides other essential forms of B-vitamins you may not get in your diet, such as P5P. '('A healthy level of B12 is 800 or higher. In the 500-800 range, you can benefit from taking B12 lozenges, specifically Methylcobalamin'; 200 - 900 pg/ml is a normal range, however, you want to aim around 800')

 

In short:

Buy Enzymatic Therapy Sublingual B12 or Country Life Vitamin B12 Sublingual Lozenges 5000mcg & Jarrow B-Right.

 

 

Edited by Mr.Nootropic, 03 June 2014 - 07:20 PM.

[nameless]

I can get my blood tested easily enough, so I can figure out if whatever I take absorbs. But thanks for the other product links. Ideally I'd prefer a 100mcg or so dose and just see how that works. I may have to break out my pill splitter.

I consider 1000% of certain B vitamins to be megadosing. It's arguable if it can cause longterm harm or not (I'd expect not, but prefer to err on the side of caution). I see no reason to take 1000+% RDA for thiamin + riboflavin, or folate if a person doesn't really need it. I'm not saying anyone is wrong for taking it, as everyone has different risk/reward mindsets. It's just I'd prefer not to megadose other vits just to get the B12. I'd rather just take B12 separately.

I am a bit curious as to the cause of my falling B12, as I noticed the past two years or so it has slowly been dropping. I guess dropping a multi and eating slightly less red meat could be a cause, but I was never a big meat eater to begin with, and I eat fish/chicken somewhat often.

[mrnootropic]

 

I can get my blood tested easily enough, so I can figure out if whatever I take absorbs. But thanks for the other product links. Ideally I'd prefer a 100mcg or so dose and just see how that works. I may have to break out my pill splitter.

I consider 1000% of certain B vitamins to be megadosing. It's arguable if it can cause longterm harm or not (I'd expect not, but prefer to err on the side of caution). I see no reason to take 1000+% RDA for thiamin + riboflavin, or folate if a person doesn't really need it. I'm not saying anyone is wrong for taking it, as everyone has different risk/reward mindsets. It's just I'd prefer not to megadose other vits just to get the B12. I'd rather just take B12 separately.

I am a bit curious as to the cause of my falling B12, as I noticed the past two years or so it has slowly been dropping. I guess dropping a multi and eating slightly less red meat could be a cause, but I was never a big meat eater to begin with, and I eat fish/chicken somewhat often.

 

 

 

Ok, Well its up to you.

I wouldn't recommend you something, that would cause you harm. If you dont listen and you buy any Pack of 100mcg B12 Tablets you're just going to end up buying a useless product.

 

The ones i have shown you have been tested  by 100's of people suffering from ME&CFS.

70% of the B12 Brands And Products that was tested were useless and didn't raise b12 levels. The 2 that was the most effective were : Country life b12 5000mcg and Enzymatic Therapy b12  . And B-Right is useful as a B Complex. The rest were useless.

 

Its not as simple as just buying a pack of b12 pills. 

Vitamin B12 injections often yield poor results, so if you think a random 100mcg pill will be ok, then go ahead.

If you are basing your life and diet of off Reccomended Daily Intakes / RDA , then its no surprise you are deficient in b12 in the first place.

 

Just out of curiosty what is your B12 level ?? Or what was it the last time you checked ?

And btw, the 5000mcg B12 is taken once every 3 days. This is why im recommending it to you ! it has been proven to raise b12 levels and its saving you a whole lot of money.

 

Why ignore me and go and buy a random pack of 100mcg Tablets? When i am recommending you one that has been proven and is recommended by 100's of people. And will save you money!.

 

I repeat. Raising B12 Levels is not as simple as buying a pack of B12 Pills. If you dont listen you will just buy a useless product. And BTW, Im not being an ass, im trying to help you!. If you listen to me, you will raise your B12 levels.

Edited by Mr.Nootropic, 03 June 2014 - 08:28 PM.

[pamojja]

 

I'm a bit curious why my B12 has been sinking the past 2 years, although I guess it could be due to possibly eating slightly less meat.

 

Being a vegetarian for 30 years and ignorant of supplementation my serum B12 arrived at 179 pg/ml (187 - 883 range) 5 years ago. 560 mcg/d brought it gradually up to 1600 pg/ml within 1 year. In an attempt to bring Homocysteine down I kept supplementing pretty constant at about 1400 mcg/d since then, but still saw variations of 400 +/- in serum. The largest drop down to 860 pg/ml after a short trial of 250 mg/d of Metformin.

 

There could be many reasons for variating levels: More or less metabolized, diet and medications.

 

 

You simply dont just buy a b12 pill and pop it. Its just not that simple, alot of brands and forms dont do anything regarding  raising B12 levels and are useless.And some forms of B12 are potentially toxic. You will forever have problems with B12 Deficiency if you dont listen.

 

Hmm, never used your brands, but raising levels didn't seem that difficult.

Edited by pamojja, 03 June 2014 - 09:30 PM.

[mrnootropic]

 

Being a vegetarian for 30 years and ignorant of supplementation my serum B12 arrived at 179 pg/ml (187 - 883 range) 5 years ago. 560 mcg/d brought it gradually up to 1600 pg/ml within 1 year. In an attempt to bring Homocysteine down I kept supplementing pretty constant at about 1400 mcg/d since then, but still saw variations of 400 +/- in serum. The largest drop down to 860 pg/ml after a short trial of 250 mg/d of Metformin.

 

There could be many reasons for variating levels: More or less metabolized, diet and medications. 

 

Hmm, never used your brands, but raising levels didn't seem that difficult.

 

 

179 pg/ml isnt as bad as i would think for a 30 year vegetarian but its still classed as a deficiency.

People with B12 levels between 200 pg/ml and 350 pg/ml are considered ''normal'' in U.S.A, So you was slighty under in the U.S.

But in Japan and Europe, the lower limit for B12 is between 500-550 pg/ml... So you was largely deficient! According to EU & JPN. 

 

But i have a feeling that the word ''normal'' doesn't necessarily mean healthy levels of B12 in the U.S.A, considering the diet of most Americans.

 

I wonder how your b12 levels has affected you in the past 30 years ?

Have you felt any different since you corrected your B12 Levels ? And corrected your B12 Deficiency ??

And did you have any symptoms of B12 deficiency during you time as a vegetarian ?

 

And correcting a B12 deficiency isnt as simple as it seems. Im not going to go into why, but there are many different factors.

I was just trying to tell the Original Poster the Best Brands which have been tested by 100's of people. And have been proven to be effective.

Edited by Mr.Nootropic, 03 June 2014 - 10:26 PM.

[mrnootropic]

I can get my blood tested easily enough, so I can figure out if whatever I take absorbs. But thanks for the other product links. Ideally I'd prefer a 100mcg or so dose and just see how that works. I may have to break out my pill splitter.

I consider 1000% of certain B vitamins to be megadosing. It's arguable if it can cause longterm harm or not (I'd expect not, but prefer to err on the side of caution). I see no reason to take 1000+% RDA for thiamin + riboflavin, or folate if a person doesn't really need it. I'm not saying anyone is wrong for taking it, as everyone has different risk/reward mindsets. It's just I'd prefer not to megadose other vits just to get the B12. I'd rather just take B12 separately.

I am a bit curious as to the cause of my falling B12, as I noticed the past two years or so it has slowly been dropping. I guess dropping a multi and eating slightly less red meat could be a cause, but I was never a big meat eater to begin with, and I eat fish/chicken somewhat often.

 

Yeah, i do agree with you. There is no need to megadose. And i do share you concerns.

 

And regarding your first post.. Yes, sublingual does matter. Be sure to get sublingual.

If you can get them from your doctor, then thats a good thing to do.

 

But 100mcg will be fine, if the product you are taking does get absorbed. 

As i understand you do not wish to take high such doses, then you will be fine at 100mcg, aslong as it gets absorbed.

Edited by Mr.Nootropic, 03 June 2014 - 11:08 PM.

[pamojja]

179 pg/ml isnt as bad as i would think for a 30 year vegetarian but its still classed as a deficiency.

People with B12 levels between 200 pg/ml and 350 pg/ml are considered ''normal'' in U.S.A, So you was slighty under in the U.S.

But in Japan and Europe, the lower limit for B12 is between 500-550 pg/ml... So you was largely deficient! According to EU & JPN.

 

The hospital in Europe which tested these deficient levels was as ignorant as me, and didn't even tell me about!

 

I wonder how your b12 levels has affected you in the past 30 years ?

Have you felt any different since you corrected your B12 Levels ? And corrected your B12 Deficiency ??

And did you have any symptoms of B12 deficiency during you time as a vegetarian ?

 

I consider decades long nutritional deficiencies one of the major contributing factor to my PAD diagnosed 5 years ago (80% stenosis at abdominal aorta bifurcation). Not only as vegetarian, but back-backing for in total 10 years in poor countries. With the peculiarity there that restaurants mostly almost exclusively serve meat dishes, often leaving nothing more than rice and beans. Still no specific B12 deficiency symptoms during that time (beside 7 malarias in between '94-'98, enlarged liver, serious Spondylodiscitis and Schistosomiasis afterwards..), except a vision impairment for short moments.

 

Since my diagnosis I fought back with high-dose orthomolecular supplementation which increased pain-free walking distance from 300-400 meter to 1 hour within one year, now at 2 hours.

[nameless]

Its not as simple as just buying a pack of b12 pills. 
Vitamin B12 injections often yield poor results, so if you think a random 100mcg pill will be ok, then go ahead.
If you are basing your life and diet of off Reccomended Daily Intakes / RDA , then its no surprise you are deficient in b12 in the first place.
 
Just out of curiosty what is your B12 level ?? Or what was it the last time you checked ?
And btw, the 5000mcg B12 is taken once every 3 days. This is why im recommending it to you ! it has been proven to raise b12 levels and its saving you a whole lot of money.
 
Why ignore me and go and buy a random pack of 100mcg Tablets? When i am recommending you one that has been proven and is recommended by 100's of people. And will save you money!.
 
I repeat. Raising B12 Levels is not as simple as buying a pack of B12 Pills. If you dont listen you will just buy a useless product. And BTW, Im not being an ass, im trying to help you!. If you listen to me, you will raise your B12 levels.

I haven't chosen any brand yet, so am not ignoring you. I was just asking here for general opinions. There aren't a ton of 100mcg tablets to begin with, so may go with the higher dose every couple of days, or something like that. And again, I can figure out what absorbs or not simply by blood tests (I can simply call my doc and ask for a script). By the way, around how long should it take for a decent product to raise blood levels? 2-3 months good enough?

And my B12 was around 300-330 ... I haven't gotten a copy of my bloodwork yet, so forget the exact number. To many doctors in the US, that probably would be considered normal, buy my endo thought it a bit low, hence the 100mcg recommendation. So it's lowish, but not a major deficiency or anything like that.

In years past, it would usually come in around 500-600. I noticed last year is going down a bit, into the low 400s. And this year it's 100 pts lower. There could be some lab variation there, or just something a bit different in my diet, I guess (not sure what it could be, eating the same). I tend to have a lot of weird symptoms that would match a B12 deficiency, but since I had these symptoms even when my B12 levels were normal, I wouldn't think it'd be a cause.

[mrnootropic]

I haven't chosen any brand yet, so am not ignoring you. I was just asking here for general opinions. There aren't a ton of 100mcg tablets to begin with, so may go with the higher dose every couple of days, or something like that. And again, I can figure out what absorbs or not simply by blood tests (I can simply call my doc and ask for a script). By the way, around how long should it take for a decent product to raise blood levels? 2-3 months good enough?

And my B12 was around 300-330 ... I haven't gotten a copy of my bloodwork yet, so forget the exact number. To many doctors in the US, that probably would be considered normal, buy my endo thought it a bit low, hence the 100mcg recommendation. So it's lowish, but not a major deficiency or anything like that.

In years past, it would usually come in around 500-600. I noticed last year is going down a bit, into the low 400s. And this year it's 100 pts lower. There could be some lab variation there, or just something a bit different in my diet, I guess (not sure what it could be, eating the same). I tend to have a lot of weird symptoms that would match a B12 deficiency, but since I had these symptoms even when my B12 levels were normal, I wouldn't think it'd be a cause.

 

 

 

Ok,

 

Yeah 300-330 is considered normal in the u.s. 

Like you said you're b12 levels are most likely due to the fact you're not eating red meats as much or at all.

Edited by Mr.Nootropic, 04 June 2014 - 08:29 AM.

[albedo]

I can get my blood tested easily enough, so I can figure out if whatever I take absorbs. But thanks for the other product links. Ideally I'd prefer a 100mcg or so dose and just see how that works. I may have to break out my pill splitter.

I consider 1000% of certain B vitamins to be megadosing. It's arguable if it can cause longterm harm or not (I'd expect not, but prefer to err on the side of caution). I see no reason to take 1000+% RDA for thiamin + riboflavin, or folate if a person doesn't really need it. I'm not saying anyone is wrong for taking it, as everyone has different risk/reward mindsets. It's just I'd prefer not to megadose other vits just to get the B12. I'd rather just take B12 separately.

I am a bit curious as to the cause of my falling B12, as I noticed the past two years or so it has slowly been dropping. I guess dropping a multi and eating slightly less red meat could be a cause, but I was never a big meat eater to begin with, and I eat fish/chicken somewhat often.

 

Have you ever considered measuring Holo-TC which gives an indication of your capability of absorbing B12 from your diet or supplementation?

 

These two links should guide you:

 

Measuring and Interpreting Holo-Transcobalamin (Holo-Transcobalamin II)

http://www.clinchem....t/48/3/407.full

 

Holo-transcobalamin is an indicator of vitamin B-12 absorption in healthy adults with adequate vitamin B-12 status

http://ajcn.nutritio.../85/4/1057.long

 

I normally run both tests and started to look more closely to Holo-TC. My lab has the following reference ranges (sorry, they are in pmol/L so you need to convert). In brakets I indicate what I measured averaging over several years (I supplement too)

 

Vit B12: 120-780 pmol/l (580)

Holo-TC: >20 pmol/L (>120)

[pamojja]

560 mcg/d brought it gradually up to 1600 pg/ml (187 - 883 range) within 1 year.

 

Vit B12: 120-780 pmol/l (580)

Holo-TC: >20 pmol/L (>120)

 

I tested > 128 pmol/l once ( > 50). Same holo-TC but almost double the serum cobalamin. How much B12 do you take?

[nameless]

Have you ever considered measuring Holo-TC which gives an indication of your capability of absorbing B12 from your diet or supplementation?

Hmm... never heard of that test before. But thanks for the info. If my B12 isn't higher next time, I can ask for that.

One interesting thing is when I took a decent multi (AOR MultiBasics) my B12 was always quite decent. After dropping it, and perhaps cutting out meats a little bit, my B12 has slowly sunk over the past year or two. So I am guessing I can absorb it okay, just that I may not be eating enough meat (maybe)?

I don't know, I still eat chicken/fish probably 2-3x a week, and maybe some form of red meat, such as a buffalo burger, once a week, or every 2 weeks. I would have thought that would be enough to keep my B12 decent, as it's not like I am a vegetarian. I don't know how much meat most people eat though... it's not like I gobble large amounts down daily.

[albedo]

 

Vit B12: 120-780 pmol/l (580)

Holo-TC: >20 pmol/L (>120)

 

I tested > 128 pmol/l once ( > 50). Same holo-TC but almost double the serum cobalamin. How much B12 do you take?

 

Summing over all supplements, I am cycling for a period of time with 650 mcg (o/w 500 as methylcobalamin).

[timar]

One interesting thing is when I took a decent multi (AOR MultiBasics) my B12 was always quite decent. After dropping it, and perhaps cutting out meats a little bit, my B12 has slowly sunk over the past year or two. So I am guessing I can absorb it okay, just that I may not be eating enough meat (maybe)?

I don't know, I still eat chicken/fish probably 2-3x a week, and maybe some form of red meat, such as a buffalo burger, once a week, or every 2 weeks. I would have thought that would be enough to keep my B12 decent, as it's not like I am a vegetarian. I don't know how much meat most people eat though... it's not like I gobble large amounts down daily.

 

This may be an indication that you don't absorb B12 very well, as you eat plenty of animal foods which should provide sufficient B12 for most people. AOR MultiBasics however provides a hefty dose of 650 mcg, which is a hundred times more than even the most meat-heavy diet will provide and enough to overcome deficiencies in Intrinsic Factor by facilitating passive absorption.

 

In fact, a subclinical B12 deficiency due to a lack of Intrinsic Factor is a rather common condition. There is a considerable genetic diversity regarding the absorption of certain micronutrients (i.e depending on the degree and continuity to which your ancestors' diet included animal products). This is a major reason why I recommend to take a multivitamin.
 

Edited by timar, 08 June 2014 - 09:39 AM.

[mrnootropic]

 

This may be an indication that you don't absorb B12 very well, as you eat plenty of animal foods which should provide sufficient B12 for most people. AOR MultiBasics however provides a hefty dose of 650 mcg, which is a hundred times more than even the most meat-heavy diet will provide and enough to overcome deficiencies in Intrinsic Factor by facilitating passive absorption.

 

In fact, a subclinical B12 deficiency due to a lack of Intrinsic Factor is a rather common condition. There is a considerable genetic diversity regarding the absorption of certain micronutrients (i.e depending on the degree and continuity to which your ancestors' diet included animal products). This is a major reason why I recommend to take a multivitamin.
 

 

 

I agree with you. Most definitely.

 

However, why are you recommending a product that contains Cyanocobalmin ??

Just do some quick research on Cyanocobalamin. Cyanocobalamin is not found in Nature and is not a natural Vitamin. Not only that, but it is useless compared to other forms of B12.

 

I've already told the O.P what the best types & brands of vitamin b-12 are.

You have to take Methyl-Cobalamin.... Methyl-Cobalamin is the Activated form of B12.

Cyanocobalmin is just useless when compared to Methyl-Cobalamin.  

 

Sublingual is also the best way to take B12, alongside a B-Complex such as Jarrow B-Right.

If you have trouble with Absorption like @timar suggested. Then you need to take Sublingual B12.

 

Edited by Mr.Nootropic, 08 June 2014 - 10:28 AM.

[pamojja]

 

 

Vit B12: 120-780 pmol/l (580)

Holo-TC: >20 pmol/L (>120)

 

I tested > 128 pmol/l once ( > 50). Same holo-TC but almost double the serum cobalamin. How much B12 do you take?

 

Summing over all supplements, I am cycling for a period of time with 650 mcg (o/w 500 as methylcobalamin).

 

Thanks. Shows how different the intake has to be to reach equal Holo-TC levels.

 

However, why are you recommending a product that contains Cyanocobalmin ??

 

Timar usually recommends 1 capsule of the LEF's Two-per-Day, which would come to 150 mcg Methylcobalamin.

[nameless]

This may be an indication that you don't absorb B12 very well, as you eat plenty of animal foods which should provide sufficient B12 for most people. AOR MultiBasics however provides a hefty dose of 650 mcg, which is a hundred times more than even the most meat-heavy diet will provide and enough to overcome deficiencies in Intrinsic Factor by facilitating passive absorption.
 
In fact, a subclinical B12 deficiency due to a lack of Intrinsic Factor is a rather common condition. There is a considerable genetic diversity regarding the absorption of certain micronutrients (i.e depending on the degree and continuity to which your ancestors' diet included animal products). This is a major reason why I recommend to take a multivitamin.

You may be right there. For some reason I assumed multibasics had lower levels of B12 but it's been a while since I took it, and forgot the numbers. I only took 1 cap/daily most of the time, or at most 2, so figure it was approx. 300mcg/daily I was taking -- still more than people get from diet.

Although back when I took a generic 'one a day' type of vitamin, I believe my B12 was still quite normal, and that was at 18mcg/daily or so. But that was at least 5+ years ago, maybe longer, so perhaps I simply don't absorb it as well as I did when I was younger. Or I don't need a lot via supplementation to get my levels up.

Edited by nameless, 08 June 2014 - 08:11 PM.

[rejwan]

 

Thanks for the reply.

I'm not a big fan of megadosing some of the Bs, especially if I have no evidence I am deficient in them (B12 being excluded). I've had my folate levels tested in the past, and I have plenty.

And yep, I plan to look for Methylcobalamin. It's just that everyone seems to go with these super megadoses of the stuff.

 

Ok good

 

I never said megadose lol. I said take 1 capsule a day and you will be fine. 1 Capsule a day Is not Megadosing.

The main reason im telling you to get B-Right is because Jarrow's B12 has proven & tested to Elevate B-Vitamin Levels, whilst other brands failed to do so.

 

We have tested various other forms and brands but Jarrow Formulas B-Right & Enzymatic Therapy B12 & Country Life Vitamin B12 Sublingual came out on top. And if you dont get Jarrow Formulas or the other 2 brands, then i cant guarantee you any benefit or results. Its up to you. 

 

Enzymatic Therapy B12 is a good source & Country Life Vitamin B12 Sublingual is also a good source.

 

You simply dont just buy a b12 pill and pop it. Its just not that simple, alot of brands and forms dont do anything regarding  raising B12 levels and are useless.And some forms of B12 are potentially toxic. You will forever have problems with B12 Deficiency if you dont listen. 

 

Sublingual Vitamin B12 is also the best way to take B12, But the B-Right provides other essential forms of B-vitamins you may not get in your diet, such as P5P. '('A healthy level of B12 is 800 or higher. In the 500-800 range, you can benefit from taking B12 lozenges, specifically Methylcobalamin'; 200 - 900 pg/ml is a normal range, however, you want to aim around 800')

 

In short:

Buy Enzymatic Therapy Sublingual B12 or Country Life Vitamin B12 Sublingual Lozenges 5000mcg & Jarrow B-Right.

 

 

 

 

One question on sublinguals: As we all know, when taking a sublingual we bypass the liver metabolism. Does this mean that sublinguals are highly ineffective for having the B12 stored in the liver for future? Or this way or that way, because it ultimately reaches the liver, will it store most of them? Or...... Most of them is excreted without getting stored compared to GI absorption?

Edited by rejwan, 02 August 2014 - 10:58 PM.

[rejwan]

Some research points out that high doses of B's are beneficial, especially for the elderly, latest example I read:

 

http://www.medpageto...Neurology/28740

 

I also remember reading somewhere that although B12 appears somewhat high in some people it does not appear to reach certain parts of the brain in brain scans (cerebrial part, I guess?) so taking high doses (actually most B's seem in one tablet seem high) and making B's more dense in blood allows more B's enter that part of the brain.

 

 

Edited by rejwan, 02 August 2014 - 11:08 PM.

[rejwan]

I would like to reask:

 

One question on sublingual B-12's: As we all know, when taking a sublingual we bypass the liver metabolism. Does this mean that sublinguals are highly ineffective for having the B12 stored in the liver for future? Or this way or that way, because it ultimately reaches the liver, will it store most of them? Or...... Most of them is excreted without getting stored compared to GI absorption?

[jroseland]

I need to create a concise presentation comparing the forms of Vitamin B12, this is is what I came up with. Is this an accurate synopsis? Anything major I'm missing?