Hi, I am looking into ursolic acid for its immunomodulatory, anti-inflammatory, androgenic (maybe), and anti-catabolic effects. However, it is at least a mild and perhaps a strong GABA transaminase inhibitor (conflicting studies). While I could probably use a little GABAta inhibition, I don't wanna screw my GABAergic system up too much more (had a long acute w/d from a comparatively low daily dose of alcohol, then my genius GP put me on Xanax, which I used for a month and of course talk about "kindling"...).
Any thoughts? Or any th17/il17 inhibitors that don't have a bunch of additional modes of action? (There is a really small thread elsewhere but it's a bit old. I have a bad reaction to circumin at therapeutic doses unfortunately, probably due to its MAOi property)