I don't know if its caused by depression or what, but low to moderate doses of amphetamine makes me dysphoric. This happens to some people, does anyone know of a way to counteract it? The only reliable way I've found is taking benzodiazepines at the same time but thats in no way sustainable.
Amphetamine dysphoria - How to counteract it
#1
Posted 11 July 2014 - 05:24 PM
I don't know if its caused by depression or what, but low to moderate doses of amphetamine makes me dysphoric. This happens to some people, does anyone know of a way to counteract it? The only reliable way I've found is taking benzodiazepines at the same time but thats in no way sustainable.
#2
Posted 11 July 2014 - 05:26 PM
I used to have this problem the 3th dose of the day of amphetamine, memantine reversed that problem for me.
#3
Posted 11 July 2014 - 05:26 PM
I take Lyrica (pregabalin) everyday. It is not a benzodiazepine, and it provides me anxiety relief as well as a "mood brightening" effect. A cheaper alternative is Neurontin (gabapentin). It is prescribed often to patients with anxiety in my region, and I think it would be appropriate in your case.
Consult with your doctor about these gabapentioids and he or she should give you the appropriate advice.
----I do take a benzodiazepine everyday, Klonopin (clonazepam) and I do just fine, and I also take memantine and it has provided good results.
I take 70mg. of Vyvanse equipotent to 30mg. of Dexedrine (dexamphetamine) and 30mg. of dexamphetamine IR daily for a total of 60mg. d-amp daily.
Edited by Warhawk, 11 July 2014 - 05:29 PM.
#4
Posted 11 July 2014 - 07:40 PM
Amphetamine never gave my quite a bit of a dysphoria, but (M)ethylphenidate and modafinil yes and not mild ones...
#5
Posted 11 July 2014 - 07:49 PM
Amphetamine never gave my quite a bit of a dysphoria, but (M)ethylphenidate and modafinil yes and not mild ones...
It seems that you have problems with dopamine reuptake inhibitors rather than dopamine agonists, e.g. methylphenidate is a DRI; modafinil is also a weaker DRI, with additional action as a D2R partial agonist (the highest efficacy at the schizophrenia receptor that medicine is willing to mess with). This may explain some of the dysphoric actions-- you may need to avoid DRIs with any stacks.
#6
Posted 28 January 2016 - 10:37 AM
Also tagged with one or more of these keywords: amphetamine, stimulants, depression
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