So I had the idea of hybridizing nootropic compounds together to form all new compounds, and I came up with a few that looked kind of interesting. For example, the first idea was to combine Coluracetam and Phenylpiracetam to target dopamine and acetylcholine simultaneously to capture the anxiolytic/antidepressant benefits of Coluracetam, while borrowing some of the anti-fatigue, creativity, energy and motivational benefits of Phenylpiracetam, reducing the risk of relapse for those battling mental illness. This soon evolved into a whole portal of ideas and combinations with multiple permutations. I started editing the chemical structures for some of these, until a few of them caught my eye for their uniqueness. For the parent molecules, I used Piracetam, Oxiracetam, Coluracetam, Phenylpiracetam, Modafinil, Unifiram, NSI-189 and a few others. There are also a few original ones that I threw in for good measure. Here they are:
Molecule 1.PNG 22.61KB 3 downloads Molecule 3.PNG 11.03KB 3 downloads Molecule 2.PNG 9.45KB 3 downloads Molecule 4.PNG 28.42KB 4 downloads
Molecule 6.PNG 24.15KB 4 downloads Molecule 5.PNG 25.83KB 3 downloads new compound.PNG 17.26KB 3 downloads new compound 2.PNG 20.21KB 3 downloads
I'm no wizard at neuropharmacology, so I have a few questions. First, are these feasible, and how much would it cost to get these synthesized? Does anyone have input or advice about these? I know some of these could potentially be dangerous or harmful, but the goal was to maximize benefits and minimize risk. The first one is the Coluracetam-Phenylpiracetam hybrid, (Phenylcoluracetam, if you will, ) The 6th one is pretty similar, but it bears some resemblance to the DMT molecule. I think it's different enough, though that it wouldn't produce hallucinations. It also might be somewhat of a legal grey-area. The 7th structure is a hybrid of Modafinil and Oxiracetam, (Oxirafinil?) Number 8 has some resemblance of NSI-189 as well as Modafinil and maybe Unifiram. I took care to use compounds with a good ratio of safety and efficacy. I couldn't find information about any of these, they appear to be new compounds as far as I can tell. Would it be a good idea to get these custom made? Any input would be greatly appreciated. Thanks.