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Neuropeptide S

nps neuropeptide s

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#1 Ezeon

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Posted 08 August 2014 - 08:09 PM


Neuropeptide S seems really interesting. It promotes wakefulness, locomotion, reduces anxiety and improves memory. This is an unusual combination of effects in a single compound. I've ordered some and will be able to test it soon. Have anyone else tested Neuropeptide S?

 

 

 

"It appears that the combination of increased alertness and reduced anxiety produced by NPS prepares the animals to learn much better," he said. "Memory is remarkably improved after activation of their NPS system, and the effects are long-lasting, independent of content."

 

http://www.news-medi...sts-memory.aspx

 

The EEG effects from Neuropetide S is the most pronouced I've ever seen from any compound. Almost all spike and wave activity is gone at low frequencies (delta and theta) and power is drastically increased at high frequencies (alpha, beta, gamma). Unfortunately, I can find no reports about EEG coherence.

http://usdbiology.co...Wakefulness.pdf



#2 Infinite1

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Posted 29 October 2014 - 05:04 PM

Wow, your not kidding. The NeuroScience article is quite impressive, those frequency domain spectral graphs say it all. Interested to hear how your trial went?  



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#3 Infinite1

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Posted 30 October 2014 - 12:10 PM

*Time domain frequency band graphs. Not sure why I wrote frequency domain. 



#4 Ezeon

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Posted 30 October 2014 - 04:03 PM

The trail was a success, and I got to confirm what I already knew. However, I doubt my results will be of use to many other people.

 

I have a asn107ile mutation (rs324981 A->T) on both DNA strands for the NPSR1 gene (the gene that encodes the Neuropeptide S receptor). This mutation leads to almost a complete loss of function (less than 1% remaining function in some cases) of the NPS receptor as you can see in the link below (mutation labeled pNPSR1-Asn107 in the graph).

 

Ref:

http://www.plosone.o...4/originalimage

http://www.plosone.o...al.pone.0029523

 

I'm very interested in hearing what effect others might get from NPS though.


Edited by Ezeon, 30 October 2014 - 04:13 PM.


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#5 mrak1979

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Posted 13 February 2017 - 07:14 PM

Hi Ezeon, can you let us know where you acquired neuropeptide s? Very interested in this. Thanks.







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