• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

Friend's father needs help, stat. Thoughts, please!

stroke meningitis dementia

  • Please log in to reply
9 replies to this topic

#1 sdcox

  • Guest
  • 4 posts
  • 2
  • Location:Brooklyn, NY

Posted 26 August 2014 - 02:26 AM


Hello all

 

I am a newcomer to the nootropics/brain health and enhancement field. I have been lurking around here and reddit for about a month, reading whatever I can find, working on my own stack, but now find myself with an urgent request for help.

 

My dearest friend's father (M, 70, fairly healthy previous), after recent crippling head and neck pain was FINALLY diagnosed with viral meningitis -- he is elderly, though by all accounts a very active, healthy, and very cheerful, good natured man. He's a prince among men, honestly, a liberal minded pastor and lifelong homeless community advocate. 

 

So, after his hospitalization and strange non-recovery from the meningitis, he was given a brain scan and it was found he had two undiagnosed small strokes, which were apparently hidden by the meningitis, which probably compounded his serious problems.

 

Now, he's a completely different person. He has all the signs of quick onset dementia. He's agitated, insecure, he can't remember how much he is sleeping. He is convinced he isn't sleeping at all, but in fact he is. He's paranoid, needy, and volatile--desperate not to be left alone. He is finally getting good top quality care but it is looking late in the game (his previous doctor told him his pain was "due to age, and he had to get used to it". F$%^ing quack).

 

Anyway. After learning about all the wonderful supplements and nootropics that can assist brain health, especially age related dementia, I think that this wonderful man could be helped -- but I am a rank beginner and certainly have little of the knowledge he could use.

 

I know bacopa and piracetam have been beneficial to those with alzheimers and dementia, but what else would be of use?

 

This is an awesome community, full of brilliant folks, and I can't think of a better place (besides his doctors office) to ask about this.  I would be truly, truly grateful for any advice you all might have for us. 

 

thank you!!

 

edit; word usage.


Edited by sdcox, 26 August 2014 - 02:27 AM.


#2 Bateau

  • Guest
  • 165 posts
  • 67
  • Location:Newport City
  • NO

Posted 26 August 2014 - 04:27 PM

I'm sorry you haven't gotten more help.

 

Unfortunately when it comes to dementia and age related cognitive decline, we have a wide variety of substances that will probably help and no data to suggest which ones are better than the others.

 

What I've found is that daily dosing has to be practical. You cant tell a person with dementia/cognitive decline to weigh out 2.4 grams of piracetam twice a day. Its too difficult, too time intensive, and tastes like absolute shit (negative reinforcement), and is also way too hard for them to procure. This pretty much removes all racetams from the picture. If you feel differently, then I would suggest Oxiracetam out of the racetams. More expensive, but aside from piracetam, its the most studied in cognitive decline, is likely more effective at reducing symptoms (at least 1 human study and several animal studies to suggest that) and has no bad taste, unlike other racetams.

 

What I would suggest is some Bacopa, GinkGold (patented ginkgo extract with greater efficacy than other ginkgo extracts), and some huperzine A.

 

All fairly cheap, pilled (easy to take), readily available, and should be quite effective at reducing cognitive decline. Allow some time to pass before giving up on the bacopa and ginkgo, they take about a month for effects to manifest.

 

Edit: the data on ginkgo and strokes is kinda iffy, seems to reliably improve memory in those who already had a stroke but some shoddy data suggests ginkgo may increase stroke risk.


Edited by Bateau, 26 August 2014 - 05:14 PM.


sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#3 sthira

  • Guest
  • 2,008 posts
  • 406

Posted 26 August 2014 - 05:14 PM

Has your friend looked into possibly enrolling his father into a clinical trial?

I don't know if this would be a helpful link or not:

http://m.alz.org/clinical-trials.asp

#4 purpleblue

  • Guest
  • 15 posts
  • 2
  • Location:Earth

Posted 26 August 2014 - 05:22 PM

Hi,

 

Well please make sure you don't waste time with any of the detox tea, and all that type of herbal stuff.

(I'm not saying anything natural is useless, BUT most of the marketed natural/herbal stuff is useless.)

 

 



#5 sdcox

  • Topic Starter
  • Guest
  • 4 posts
  • 2
  • Location:Brooklyn, NY

Posted 26 August 2014 - 07:49 PM

I appreciate all the input. 

 

Bateau, thanks for all your suggestions. I agree the racetams could be a problem -- though do you believe a capsuled version might be helpful? I wasn't sure if there are issues with capping, as I haven't tried it myself.

 

I'll pass these along and hope for the best. 



#6 Bateau

  • Guest
  • 165 posts
  • 67
  • Location:Newport City
  • NO

Posted 26 August 2014 - 09:15 PM

Capsules are great. Just more expensive to buy pre-capped (and i seriously question legitimacy unless branded European products) and time consuming to cap them yourself. But racetams are fine, and capsuling overcomes the other practical issues i was talking about. Phenylpiracetam Oxiracetam Piracetam and maybe Noopept (dont know if stroke was included in THIS study) all have human trials showing cognitive improvements in patients with stroke.

 

Piracetam is generally considered to have the least promise and has been outperformed by each of the previously mentioned racetams in at least one study in humans (totaling 3 different dtudies), we know practically nothing about phenylpiracetam even though there's apparently 7 russian studies testing it in dementia and stroke, where it was apparently effective.

 

Honestly cant suggest which monotherapy is the best, or even if adjunct therapy with more than one racetam would be better than monotherapy. Oxi and Phenyl are more expensive, noopept powder is dirt dirt cheap, like pennies a day, but practically IMPOSSIBE to dose properly, piracetam is probably the weakest. Aniracetam and Pram dont have human evidence to support efficacy, but that doesn't mean they wont be effective. Aniracetam and Noopept will have more mood stabilizing effects though, they reduce anxiety and depression. A relevant bonus that is totally separate from whether or not they will effectively reduce cognitive decline.

 

Like I said earlier, tons of options with no clear evidence which will be the best. Piracetam should generally be considered the least effective though, beyond that its personal preference as to which to suggest starting with.

 


Edited by Bateau, 26 August 2014 - 09:18 PM.


#7 Bateau

  • Guest
  • 165 posts
  • 67
  • Location:Newport City
  • NO

Posted 26 August 2014 - 09:28 PM

Another note on mood stabilizing. Most if not every, herbal nootropic is mood stabilizing, reducing anxiety and/or depression. Again this gives you a wide variety of choices, but bacopa and gotu kola are the most studied/promising of the herbal anxiolytic nootropics and polygala tenuifolia is the most promising/studied antidepressant herbal nootropic. Coincedientally they were the most respected nootropics in Ayurveda and Traditional Chinese Medicine. Polygala is crazy hard to find but the other two are readily available.

 


Edited by Bateau, 26 August 2014 - 09:29 PM.


#8 ovecta

  • Guest
  • 68 posts
  • 6

Posted 26 August 2014 - 10:59 PM

Cerebrolysin is a relatively safe means of treating neurological disorders ranging from dementia to stroke, its got alot of clinical data backing it up but the only downside is that it has to be administered via intra muscular injection, it can be purchased without issue though from overseas suppliers, my advice would be contact a doctor and present this idea of treatment, bringing printed studies might help convince him/her to consider this treatment option... it seems like too valuable an option not to consider!

#9 Flex

  • Guest
  • 1,629 posts
  • 149
  • Location:EU

Posted 27 August 2014 - 12:57 AM

-Edit-


Edited by Flex, 27 August 2014 - 12:57 AM.


sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#10 Flex

  • Guest
  • 1,629 posts
  • 149
  • Location:EU

Posted 27 August 2014 - 02:14 AM

Look into Neuroaid

http://www.neuroaid....ng_NeuroAid.pdf

 

Chinese Herbs do have interresting actions but one problem is that they thin the blood, which could cause inner bleedings when combined whit other blood thinning stuff and/or solely when high dosaged in the case they inhibit coagulation.

This in turn could (in the very worst case) also lead to a stroke.

So it would be good if You ask a Doc for advice.

 

In the case of Neuroaid, I think that they do supposedly suggest a maximum dosage in their package insert to prevent any side-effects.

The first 5 herbs which are mentioned (Astragali..), have positive effects on the outcome regarding ncbi.

 

If I find any other herbs or compounds, I will post it here.

 

Wish the best 







Also tagged with one or more of these keywords: stroke, meningitis, dementia

1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users