I've been benefitting from creatine monohydrate supplementation and was curious if skipping the BBB would be more effective in raising brain creatine and ATP levels. Will there be absorption or toxicity issues?
Will high doses be necessary if you are bypassing the blood brain barrier? Since Creatine has difficulty penetrating the BBB you must saturate your blood in order to get enough to pass through the BBB to your brain, but perhaps thats not necessary if intranasal administration yields the same amount of brain creatine at a much lower dose.
I intend to use a nasal spray solution, not to snort.
