8 replies to this topic

[Anja from Sweden]

Hello.

 

I read on wiki that MDPV was researched as alternative for methylphenidate 1960 by Boehringer Ingelheim

Why is there a ban of it in the US and EU 2015.

What are the bad sides instead of ritalin?

[Mind_Paralysis]

The ban is probably as a result of misuse by addicts, since it was sold as a recreational designer-drug, starting in the mid-2000's.

 

And hey man, MDPV was kind of a bust, seems like it's waaay too addictive, and the Norepinephrine-onset it stimulates f*ck's most people up pretty quick - the panic-attacks caused by methylphenidate is apparently NOTHING compared to what MDPV causes.

It's seems like a piece-of-sh*t man... focus on some other chemical, if you want to research alternative ADHD-drugs - if that is your goal.

 

When it comes to using compounds to treat certain neurological deficiencies, ACCURACY is more important than potency. Hit the right parts... and you won't need much - the brain will sort it out.

Methylphenidate and Amphetamines are in general VERY inaccurate, and therefore VERY unpleasant when used medically.

 

Instead, take a genetic test, on 23andMe.com, and determine which genes you have errors in - DAT ( dopamine transport), NET (norepinephrine transport), or DRD4 ( dopamine receptor, type 4)- are some of the most common faulty genes in ADHD.

 

IF you have a DRD4 -error, and then most likely a subsequent D4 dopamine receptor -problem, then a research-chemical like A-412,997 is what you need.

 

http://en.wikipedia.org/wiki/A-412,997

 

Not MDPV.

 

It's effin' USELESS mate! Abandon research on it, and go for accuracy. It's the only way to be, man... You want to be OVERhuman, not SUB-human... And that is what incorrect optimization of your neural network will result in.

 

We want to be sharp as F***ING LASERS, man! Not retards.

 

Recreation is for suckers. But clarity, motivation, endurance - these are the things to achieve.

 

[golden1]

"recreation is for suckers" ha ha ha, why would you avoid fun in the only life you get to live?

also mdpv isn't useless and you can't conclude that or sideeffects from people using higher repeated recreational doses anyway

 

yeah he should just go buy A-412,997.. as if that is even possible or safe... 

Edited by golden1, 06 October 2014 - 01:21 AM.

[Mind_Paralysis]

Yeah... About that...

 

My last post was made very late at night, in a state of come-down from a longer use of stimulants, so I was in quite an agitated mood, and did what I always do - I project my own emotional turmoil on others.

 

Apologies to Tranyl - you had a legitimate question.

 

 

And I do enjoy recreation as well, just not through chemical alteration. My dislike for recreational drug-use comes from problems in our family with abuse, and because of my own difficulties with emotion and behavioural control - I was raised by a step-father with Narcissistic personality-disorder,  and was always chastised for failure to control my emotions - at peak efficiency.

 

As such, I have developed an immense dislike for drugs that make it more difficult to regulate emotions, as I incorrectly project my own feelings of disappointment in emotion-control, on others.

Basically, I fear any drug ( or use of a drug) which will temporarily make it more difficult for me to focus or maintain highly controlled emotions - as I have been thought poor emotion-control is an incredible SIN, which must be punished - severely.

 

 

So that's why I, at times of weakness, react the way I do, to recreational use of drugs.

 

 

As for MDPV - yes, it could have some therapeutic use, for either ADHD or some other disorder - but the same can be said for crystallised Methamphetamine, but because of the increased dependence-issue, you don't see much prescribed use - if any. The same appears to be true for MDPV - hence why regular amphetamine and methylphenidate are still the go-to-drugs for ADHD.

 

And we really do need more accuracy with therapeutic use - it's better to affect less parts of the brain, if you only have problems with one perticular section.

 

If you're interested in recreational use of drugs tho', I'd recommend something like Ketamine, at SMALL doses - since it has a very good side-effect profile, and actually has a similar effect to alcohol at small doses - but without the depressive side-effects or next-day hangover. Its NMDA-effects can also be quite beneficial if you have ADHD, since over-active NMDA-receptors is one of the researched areas of ADHD-pathology right now. ( memantine and nitromemantine for instance, are also NMDA-antagonists)

[Anja from Sweden]

Hello!

I am a femal student from Sweden.I was Prescriped Ritalin Neuroleptics and SSRIs as child for 10 years.After that i had no interesst to visit doctors any more.I was a zombi. I found RCs:-)
My brain chemistry is destroyed since high dose Neuroleptics SSRI and Ritalin.So I dont think I can do more harm.
I took 3-MMC for the last 3 Years, 5 times a week 400 mg with no problems until today.But effects know are nearly gone.I liked the slight empathogenic effects,and talkativness.And i was no zombi any more,i had a life.In my opinion Ritalin and Amphetamines I was prescriped where much stronger in effects.I liked 3 MMC more than Ritalin or MDPV.

Well if i want to stop it completly I have the same problems as with Ritalin,SSRis long therm.Brain zaps,depression.So I need something else.
I read on Bluelight and eve and rave there ist 5-MAPB,or 6 APB.I have a trusted shop so no problem.
But what can I expect? I dont want something I am totally stoned or cant think anymore and sit only on a couch and hear music:-)

So what do the experts here think.Can I take 5-MAPB or 6APB longterm low dose? say 10-30 mg 5 times a week?or something else?
My body is ok,but if those drugs like 5-MAPB are psychedelic,thats not my way,nor opoides or THC or heroin.I tried all.
I need something for depression,and that I can and love to talk to people and am aktiv.
Well for sleep i am Prescriped since 9 years nitrazepam:-)20mg,so im dependent on this one too.

I want not to here that this is unhealthy or so.But for me the 3 years on 3 MMC were better than on high dose Ritalin,Amp,and SSRI.
I was no zombi any more.I was alive.Is something like 5 MAPB or 6 apb much unhealthier or dangerous than 3 mmc daily 500mg?
I choosed this way.Better a shorter live,as a live where i am a zombi.I am not Schizophrenic,ADD+Depression

Thanks for advice.

Anja from Sweden:-)

 

[Anja from Sweden]

Hello you said the research-chemical like A-412,997 is very helpful

 

But its not availibly here in sweden.PN if you know where to  A-412,997

perhaps it will help me.

 

Thanks Anja

[medievil]

ive used a combination of desoxypipradol and mdpv for ages without problems, i really love mdpv its like the god of stimulants... shame its being banned, but its called psychosis powder for a reason, i allways used it with benzos wich prevented the psychosis.

[medievil]

"So what do the experts here think.Can I take 5-MAPB or 6APB longterm low dose? say 10-30 mg 5 times a week?or something else?
"

 

Yes, but the key is to take therapeutic doses, if you take recreational doses of serotonin releasers long term you will cause severe depression.

 

Im interested in your experience with 3mmc i was interested in using that therapeutically, also take in mind i am the ONLY person here that uses chemicals like that therapeutically and knows the risks etc, everyone would say its stupid to take sero releasers or other chemicals on a daily basis, i say it is possible but i allways inform everyone about the risks and other information thats inportant, such as hearth valve damage is you take a 5th2b agonist on a daily basis long term.

 

i know my daily use of 5 meo dalt puts me at risk for that.

[Mind_Paralysis]

Hello you said the research-chemical like A-412,997 is very helpful

 

But its not availibly here in sweden.PN if you know where to  A-412,997

perhaps it will help me.

 

Thanks Anja

 

Hej, är också från Sverige, så svarar på nordmännens språk.

 

A-412,997 är en väldigt specifik drog, den verkar bara på en liten, liten del av hjärnan, på D4-receptorerna. Det är dock ett vanligt genfel i dom receptorerna om du har ADHD - därför verkar den drogen fantastiskt bra på dom med ADHD som har ett DRD4 fel i generna.

Har du dock inte det genfelet, så är det inte så säkert att A-412,997 kommer hjälpa. För att få reda på om du har just det genfelet, så kan du låta testa ditt DNA, på en tjänst som heter 23andme.com.

Dock måste du sedan ladda ner din gendata därifrån, och sedan analysera den på en annan sida, för at kunna få medicinsk data. ( dom tillhandahåller bara en klump med data åt dig, du måste trycka in den i en dator som går igenom datan själv.)

 

A-412,997 är en väldigt intressant kemikalie, den upplevs lite som metylfenidat, fast utan hjärtklappning, etc. Kan tydligen vara väldigt "diskret" - man känner sig inte HÖG på den alls.
 

Du kan köpa A-412,997 online från ett ställe som heter Tocris Bioscience ->

http://www.tocris.co...p?ItemId=348516

 

Den är dock väldigt, väldigt dyr, så det är inget jag riktigt rekommenderar, i alla fall inte förränn du har låtit testa dig för den här förändringen i D4-receptorerna, som drogen verkar på.

 

 

Om det här med gentestningen känns för avancerat, så prata med en kunnig vän eller familjemedlem som kan hjälpa dig - det är helt klart värt det! =)

 

 

När jag läser dina poster så låter det lite som om att du har provat på tok för många olika saker dock - du nämner till och med själv att du kan ha fått hjärnskador? I så fall bör du nog överväga att undersöka dom olika nya experimentella drogerna som verkar reparerande på hjärnan på olika sätt, först. Som t ex NSI-189 - en experimentell antideppressiv. Jobba på att bygga upp hjärnan främst, du måste motverka dom här skadorna du har.