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Opiate & Dexadrine In-Patient Detox Help

opiates detox withdrawal dexadrine addiction

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#1 pmacdona51

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Posted 21 October 2014 - 01:51 AM


Members, 

 

First of all, thank you in advance for anyone who takes the time to answer any of my questions, much appreciated.

 

CURRENT DRUG CONSUMPTION (DAILY, over ~18-20hrs):

·         ~150mg Oxycodone, mainly through Percocet  5mg/325mg (acetaminophen)

·         30-45mg of Dexadrine XR.  

·         ~30mg of Nicotine daily - 75% through chewing tabacco and the remainder in cigarettes.

I am prescribed 50mg of the Oxycodone, and 100% of the dexadrine with daily pickups.

 

For a variety of reasons I will not get into, my only choice is to do a home-detox, or go to a local in-patient facility to perform a detox.  Aftercare I have decided to attend a variety of programs that work with my job/life, including the SMART program.  

 

My question is this, the facility i plan on attending will not allow me to maintain my dexadrine dose.  My worry is that the dexadrine withdrawal for me has been incredibly difficult, with major agitation and depression being the most difficult to deal with and actually what ended up being the reason i got back on the opiates after a year clean (self medicating the depression).  I have been on and off SSRI's, and did not want to go down that road again.  Basically since this started 4 years ago (POST INJURY AS AN NFL PLAYER), doctors have been throwing medications at me when i have been asking for help.

 

On one hand, if I am able to get off of all 3 (which by the way the facility is NON-SMOKING/CHEWING) at the same time, and come out of the 9 day program with enough energy and mental stability to maximize the use of Aftercare, Supplement/Nutritional support, Exercise, CBT etc., then this is the best case scenerio.  However I am worried, based on past experience with Dex withdrawal, that I will be an absolute mess after i come out and not able to function in my job/life - which is critical as I only have about 14 days away from regular life.

 

To some, this may be a low dose and seem like it is achievable, however there has been 4 years of SSRI's, various high doses of Adderall/Dex, not to mention the various head injuries I suffered playing Pro-Ball.  So my brain/body is a big mess that goes beyond just what i am using now.  For example, my test levels are at 120 (i'm 32), obviously from high prolactin due to opiates.

 

However, if i can be confident that while it is going to be a painful 7-9 days, I will come out of there able to at least give myself a chance at full sobriety, i am in 100%.  But if this is too much to stop all at once in that time period, I have to look at other options.

 

I am a strong believer in fixing the chemical first, and then focusing on the behavioural afterwards, meaning it is hard to "talk" your way out of acute imbalances in your brain function.  I also believe that in my situation, this was not my choice to do this, as everything i am on or have been on has been at the advice of a doctor.  Sometimes people just need to get off the drugs and move on, and it's not all about looking at the root of "my problems". UP until this point, getting off the medications has been doctors gave me another drug that had nasty withdrawals, and now I am a mess and need to end this for once and all.

 

Thanks for any input.


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#2 Gorthaur

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Posted 23 October 2014 - 01:17 AM

Stopping all three of those at once will be absolute hell. I don't see how you could possibly go back to work after two weeks, or even two months. And if you've been on these medications for 4 years, there is no return to baseline. If you attempt to be completely sober, you will be stuck in a permanent hypodopaminergic state. Though there is no chance of getting back to "normal", there is always a chance to reduce, moderate, and control your drug usage. You can transfer to methadone, for example. Instead of dexedrine, you could take bupropion. You say that you want to "end this once and for all", but it sounds like you are in too deep to just cut this habit out of your life. You have to take ownership of it.



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#3 pro-v

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Posted 23 October 2014 - 01:49 AM

+1 to you for trying to get off of all the meds. Stopping all of that at once is dangerous though and you would be much better served by seeking out a specialist that can work around your schedule. 



#4 PhysiologicOxygen

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Posted 23 October 2014 - 03:59 AM

On the opiate side of the equation you might want to look into the below info on Ashwagandha. However with the additional data showing a reduction in alchohol cravings and social/anxiety mechanisms I would surmise it may help with the amphetmines as well. I don't know if you can get the effect oulined below because you would not be pretreating necessarily. I wonder if supplementation now would reduce tolerance or would it just maintain your current tolerance level (Either way it would help and is worth looking into). I would think maybe a slow ramp of ashwagandha during a slow taper of oxy might be worth trying prior to treatment. Once you taper to more tolerable levels introduce a bit of loperamide. Then when your dosages have been reduced go get treatment, this will give you a better chance of functioning afterwards in my uneducated opinion. Check out the bottom notes to see what else Ashwagandha has been shown to do; remove liver damage; clean up brain cell damage etc...

 

At the end of the day as with many things in life, why do goals have to be set which are extremely hard to reach? Why not tackle one problem at a time? The success from your easiest goal will assist you in mind and body on your next goal. Either way good luck to ya and if you need any other herbal advice on dealing with side effects I'll try to chime in.

 

"Withania Somnifera" or Ashwagandha:

Reduces the severity of Morphine withdrawal! (2)

These results indicate that pretreatment with Withania somnifera extract protects from the structural changes induced by morphine withdrawal potentially providing beneficial effects on the consequences related to this condition.

http://www.ncbi.nlm....pubmed/19551457

 

Reduces tolerance to Morphine leading to less morphine needed for the same analgesic effect. This root also also suppressed morphine-withdrawal (4)

Ws (100 mg/kg) also suppressed morphine-withdrawal jumps, a sign of the development of dependence to opiate as assessed by naloxone (2 mg/kg) precipitation withdrawal on day 10 of testing.

http://www.ncbi.nlm..../pubmed/9292416

 

Suppresses coughing reflex by way of talking to the opioid receptors (5)

We conclude that the polysaccharide arabinogalactan from Withania somnifera has a distinct antitussive activity consisting of cough suppression and that this action involves the mu-opioid receptor pathways.

http://www.ncbi.nlm....pubmed/25252908

 

Now I should mention, the studies call for pretreatment with Ashwagandha NOT post treatment. It seems to inhibit tolerance, and withdrawal symptoms while also protecting the liver and brain from cellular damage while also removing toxic buildup.

 

 

I noticed this trend in new research of the supplements I take occasionally. I stumbled into it when researching colloidal silver.

Here are other notable results:

There is a root that impairs mice motivation for drinking alcohol when they have access to Free Booze! (1)
Reduces panic of not having enough alcohol! This same root eliminates withdrawal symptoms including anxiety. (3)
Improves sperm quality and fertility (4b)
Suppresses growth and metastasis of ovarian cancer. (4c)
Increased the effect of Valium and limited social isolation induced behavior such as anxiety and depression(4d)
Fixes the liver and kidney damage caused by colloidal silver Nanoparticles. (6)
Reduce the side effects of lead in the brain (7)
Reduce brain damage and limit memory loss in high altitude oxygen starved mice. (8)
Protects cells against scopolamine-induced brain cell damage (9)

Root 1-9 is called "Withania Somnifera" or Ashwagandha, Enjoy!
(1) http://www.ncbi.nlm....pubmed/25115596
(2) http://www.ncbi.nlm....pubmed/19551457
(3) http://www.ncbi.nlm....pubmed/20953426
(4) http://www.ncbi.nlm..../pubmed/9292416
(4b)http://www.ncbi.nlm....pubmed/19789214
(4c) http://www.ncbi.nlm....pubmed/25264898
(4d) http://www.ncbi.nlm....pubmed/18476388
(5) http://www.ncbi.nlm....pubmed/25252908
(6) http://www.ncbi.nlm....pubmed/25248758
(7) http://www.ncbi.nlm....pubmed/24347762
(8) http://www.ncbi.nlm....pubmed/23211660
(9) https://www.jstage.j...pb...html#sec05

Reduces seizures through Gaba Modulation
Promotes Sleep in sleep deprived rats
Withanone Restricts Cancer Metastasis And Angiogenesis


Edited by PhysiologicOxygen, 23 October 2014 - 04:04 AM.


#5 pmacdona51

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Posted 23 October 2014 - 04:34 AM

Gorthaur, your response makes me a bit worried, however I have not been on Dex for 4 years, and on and off opiates for 4 years with this last run being really about 6mos, and the Dexadrine about a year.  I find it hard to believe that 'never recovering' is the only choice here.  I have 2 weeks until i have no choice but to stop the Opiates, so would a taper on opiates and a reduction to 15mg on the dex give me a better chance?  Perhaps using nicotine replacement to avoid all 3 during the opiates?

 

Pro-V, can you expand on 'dangerous', i was under the impression that neither withdrawal was life threatening?



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#6 Gorthaur

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Posted 24 October 2014 - 01:58 AM

Withdrawal from oxycodone is probably the most serious issue. It's unlikely to kill you, but that doesn't mean you won't feel like you're going to die. At the very least, you will need to take some loperamide. Kratom is another legal opiate that could help with a more extended taper. The more dramatic the change you make, the higher the probability that you will fail. 







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