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Antifreeze protein from ticks fights frostbite in mice

antifreeze

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11 replies to this topic

#1 Sanhar

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Posted 25 February 2015 - 09:36 PM


May have applications for cryonics, either at the time of procedure or as a prep beforehand while patient is still animated?

 

http://www.scienceda...50225151747.htm



#2 Antonio2014

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Posted 26 February 2015 - 08:49 AM

Well, it hasn't been tested at cryogenic temperatures. Also, the most important problem of current cryoprotectants is toxicity, and that seems to not be addressed in this study. But maybe it can be useful someday. Simply it's not clear now. More research is needed on this protein.


Edited by Antonio2014, 26 February 2015 - 08:49 AM.


#3 YOLF

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Posted 26 February 2015 - 11:48 PM

Perhaps we could design a study and apply for a grant from LC to test it? I'm sure the cryonics companies would love to help out.



#4 Sanhar

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Posted 27 February 2015 - 02:29 AM

Given how little cryonics based research I can find it might be appropriate... let's talk to them about what they think the uses might be.



#5 YOLF

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Posted 27 February 2015 - 04:08 AM

I have emails for the people at the various cryocompanies and for a few labs run by cryonicists. There may be reasons why they haven't done this already, we'll have to talk to some people. I know Ben Best was sourcing AFPs for experimentation sometime back in '13 or '14.



#6 Antonio2014

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Posted 27 February 2015 - 06:24 AM

The grant would be a great idea. I would donate to it.



#7 Danail Bulgaria

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Posted 27 February 2015 - 07:00 AM

Why not you simply contact the authors and suggest them to write a project for grant at Longecity?



#8 YOLF

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Posted 27 February 2015 - 03:00 PM

Why not you simply contact the authors and suggest them to write a project for grant at Longecity?

Not a bad idea, we could do that, but I'm skeptical over whether or not cryobiologists will want to get involved with cryonics. There is a history here, though that doesn't mean that advancements in technology doesn't benefit both of us.



#9 Danail Bulgaria

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Posted 27 February 2015 - 07:13 PM

Some of you people may try ... If they refuse, then nothing bad will happen, if they agree, then nice.



#10 Sanhar

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Posted 27 February 2015 - 07:14 PM

Definitely the first step imo is to get people who are in a position of responsibility over cryonics research to figure out if this could help them.  If they think so then someone should further a research grant request.



#11 YOLF

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Posted 27 February 2015 - 09:24 PM

So here's an excerpt of the important part that I'm going to send to those who work on this stuff.

 

 

...

We over at LongeCity keep hearing about all these great antifreeze protein discoveries and we're looking to advance cryonics technologies. LongeCity has a variety of grant and fundraiser options that we could use to help with this and we'll be seeking additional funding.

 
Perhaps we can all come together to determine what research could be most beneficial or give us some places to start?
 
Thanks,
 
Peter

 



#12 Sanhar

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Posted 28 February 2015 - 02:47 AM

 

So here's an excerpt of the important part that I'm going to send to those who work on this stuff.

 

 

...

We over at LongeCity keep hearing about all these great antifreeze protein discoveries and we're looking to advance cryonics technologies. LongeCity has a variety of grant and fundraiser options that we could use to help with this and we'll be seeking additional funding.

 
Perhaps we can all come together to determine what research could be most beneficial or give us some places to start?
 
Thanks,
 
Peter

 

 

Good work.  It's very important that we make attempts to build on opportunities like this.  It's not whether or not it turns out to be appropriate or effective that matters but that we try, because if we don't try, who will, and how will we ever know?






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