Studies can be skewed both ways. I tend to be more a believer in higher doses of vitamin with 500mg per setting. I have no problem ingesting up to 3 grams per day for antioxidant and antiviral protection. I have heard mega dosing vitamin c intraveneously has been used in cancer tumor therapy with success.
I agree on this. The kidneystone danger of vitamin C is a myth. There is, as far as I know, no valid research that shows any connection. However, if you have suboptimal kidneys to begin with, THEN there is research showing a connection.
Vitamin C has intravenously been used with success for cancer. It then acts not as an antioxidant, but as a prooxidant. However; this prooxidant acitvity is beneficial in this context.
I normally take between 3000-5000 grams of vitamin C daily.Time relase. Have been doing this for 20 years or something.