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Mitochondrial DNA repair?

mtdna dna repair mitochondria dna mutation

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#1 BieraK

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Posted 05 April 2015 - 01:41 AM


Hi
What compounds or what interventions could repair the mitochondrial DNA?

In these threads is  mentioned Kiwi, Cats Claw, Aspirin and Selenium among others
http://www.longecity...damagemutation/
http://www.longecity...repair-happend/

However to me is not clear is the repair is related to nDNA or mtDNA.... and is not clear if the supplements slows the damage process or have the potential of repair the mtDNA.

I'm also wondering if and Mitophagy could potentially clean the damaged mitochondria and then Mitochondrial Biogenesis (Sirt1, AMPK, PGC-1a) could replace it with new and healthy mitochondria without mutation in  the DNA.

The other possibiilty is that mitochondrial biogenesis creates new mitochondria but with mutation in the DNA...That why I'm thinking in the autophagy process.



 



#2 Kirito

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Posted 05 April 2015 - 07:12 AM

What a coincidence, I was just recently thinking of posting this same exact thread. And not only that, I just had some Kiwi last night.

 

 

Chaga:

Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay.

http://www.ncbi.nlm....pubmed/15630179



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Also tagged with one or more of these keywords: mtdna, dna, repair, mitochondria, dna mutation

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