2 replies to this topic

[metanoia]

So you can't take both of these at once - at least, certain sources indicate drug interactions, although it seems like MB's MAO inhibition is weak enough to possibly combine the two. I'm not a scientist - I feel nervous about making my own interpretation.

 

So, assuming I can't take both, which should I take? Is there any reason to prefer one or the other, or why you personally prefer one or the other? 

 

Do you think it would be safe to take both, assuming I'm taking a larger dosage (1-10 mg) of MB as opposed to the microgram doses some people do?

 

If it matters to your opinion, the issues I'm dealing with are related to cognition/energy, and I have a maternal family history of Alzheimer's. Still youngish (30) so I'm sure clinical significance is a long way off - and intellect can mask it - but I have noticed cognitive changes, particularly in word choice and substitution - these are studied markers of dementia.

 

 

Edited by metanoia, 11 April 2015 - 06:36 AM.

[metanoia]

I didn't get much response to this but I did end up combining methylene blue and rasagiline. It's been amazing and I haven't had any problems. YMMV.

[axonopathy]

At low doses, methylene blue negligibly inhibits MAO. MB behaves similarly to the reversible antidepressant MAOI moclobamide at high doses. It is unnecessary to restrict tyramine for reversible MAO inhibitors.