198 replies to this topic

[OneScrewLoose]

 

First of all, ethylphenidate and methylphenidate (Ritalin) are NOT amphetamines!  Ritalin is close to being cocaine! Ritalin causes serotonin syndrome so does cocaine! The amphetamine Vyvanse surprisingly calms me down when the paradoxical other name for amphetamine is "speed". I think Ritalin is SPEEDIER than any of the amphetamines, though I have never tried Ritalin.

 

Please try to avoid Meth and Drugs. This was my idea 3 Years ago when the desperation due to the 1st Girl started..

I wanted to be less emphatic like her and the people arround me, stupid idea..

Now I have to run arround to reverse this besides the Cannabis alterations, the Ethylpheidate caused depression, slight PSSD and the inherent satae who I believe to be caused by a short Serotonine transporter allele

( i.e. too much serotonine) which causes pro-social behavior, lack of affect, anhedonia, anxiety ..

The alterations by stimulants and hard drugs are diverse and hard to tackle e.g. through DeltafosB, epigenetic alterations & etc.

 

http://www.longecity...eversal-thread/

 

I believe that this was one of my main sources in regards to narcissistic personality disorder:

 

http://www.medicinen...nality_disorder

https://www.bpdcentr...llmarks-of-npd/

 

will add further infos today

 

 

Just no. Ritalin dose not effect the release of serotonin. Amphetamines do to a minor extent. Ritalin is a dopamine reuptake inhibitor (like cocaine), meaning it blocks the reuptake of dopamine from the synapse, making it more available in the synapse where it is active. Amphetamines go a step further and reverse the transporter (instead of just blocking it), causing the release of dopamine from the cells to the synapse instead of the norm of the other way around. This makes amphetamines like Adderall stronger than Ritalin.

Cocaine also does not cause serotonin syndrome. Ritalin and cocaine have the same mechanism, it's just that cocaine is stronger, has a shorter duration of action, and is usually insufflated instead of ingested, skipping the first-pass liver metabolism. These things are what make cocaine much speedier than Ritalin. It may seem small, but the difference is huge, despite having the same exact mechanism (dopamine reuptake inhibition).

[gamesguru]

the red pill:

go from being omega to alpha. spin lots of plates, don't cry when you drop and shatter one.

but good luck, it's exceedingly difficult to change others' perception of you.

[Duchykins]

Ritalin is not an amphetamine but it does affect serotonin.  However, like theanine, its unclear what is going on, but studies with conflicting results definitely show that ritalin is doing something with serotonin, either directly or indirectly, with transport or reuptake, etc.  Yeah we all know ritalin as a DNRI, but that doesn't mean its effects are actually restricted to dopamine and norepinephrine only.  Just consider bupropion.  Also, serotonin syndrome is a known risk in adderall overdose.  The bottom line is that we have a lot more to learn about the mechanisms of not just these drugs but most on the market.

 

I also wanted to add that OP doesn't really know the major chemical cause of the pleasure sensations associated with lust, etc.  That he thinks he can tell the difference between dopamine-induced pleasure and oxytocin-induced pleasure without scientific measurements is absurd in the highest degree primarily because there always a hodgepodge of biochemistry sorcery happening whenever we feel good.  Tons of things come into play when we experience pleasure, including substances most wouldn't think of like norepinephrine, glutamate, acetylcholine, histamine, etc.

 

OP should just try to keep a rubber band around his wrist to snap whenever he gets the undesirable urges.

[normalizing]

ritalin doesnt feel anything like cocaine, nor amphetamine and the least anything to do with serotonin. its just some very dirty synthetic stimulant that never gave me a high and im shocked to hear some people get high on that crap.

[eon]

Was this for me? Please elaborate. I get the last part. I can't change how someone feels about me but when one has more important things to do, it would be nice to block out the emotions and get on with life. Even Stephen Hawking don't get women! 

 

the red pill:

go from being omega to alpha. spin lots of plates, don't cry when you drop and shatter one.

but good luck, it's exceedingly difficult to change others' perception of you.

 

[eon]

Have you tried coke? I believe Ritalin is "slow release" coke. Lasts all day. Coke lasts a few minutes. Coke is an SNDRI, not just a NDRI. Even St. Johns Wort is listed as a SNDRI! Which was why I was snappy and had a temper when I used it for years! This was a time when I lacked research and knowledge. I had serotonin syndrome. I got things done but I wasn't friendly. I was "wild" and easy to snap at anyone. I believe this was stereotypical behavior when one is on Ritalin and or coke. Actually one guy suspected I was on coke! It was St. John's Wort combined with SAMe and 5-htp!

 

ritalin doesnt feel anything like cocaine, nor amphetamine and the least anything to do with serotonin. its just some very dirty synthetic stimulant that never gave me a high and im shocked to hear some people get high on that crap.

 

Edited by eon, 14 June 2015 - 10:15 AM.

[normalizing]

 

Have you tried coke? I believe Ritalin is "slow release" coke. Lasts all day. Coke lasts a few minutes. Coke is an SNDRI, not just a NDRI. Even St. Johns Wort is listed as a SNDRI! Which was why I was snappy and had a temper when I used it for years! This was a time when I lacked research and knowledge. I had serotonin syndrome. I got things done but I wasn't friendly. I was "wild" and easy to snap at anyone. I believe this was stereotypical behavior when one is on Ritalin and or coke. Actually one guy suspected I was on coke! It was St. John's Wort combined with SAMe and 5-htp!

 

ritalin doesnt feel anything like cocaine, nor amphetamine and the least anything to do with serotonin. its just some very dirty synthetic stimulant that never gave me a high and im shocked to hear some people get high on that crap.

 

 

was coke addict for years. ritalin feels 0% like coke to me. i did coke for years and years, and i was put on ritalin in time over ADHD or w/e you call it now days, had zero relation. i did not feel a single europhoric high ever on that synthetic garbage. i do remember doing some street amphetamines, 180 degree in difference too. so, basically ritalin is GARBAGE. zero dopamne, zero serotonin, at least for me.

[gamesguru]

 

I can't change how someone feels about me but when one has more important things to do, it would be nice to block out the emotions and get on with life. Even Stephen Hawking don't get women! 

 

True, especially if you've already made a bad first impression on the person, and been labeled as a friend for a period of many months. (read: forget this girl, plan for future successes)  Your chances with a random women at a bar or party are much better than one you've met at work, the gym or grocery store.  Alcohol is dis-inhibiting her, everyone is sociable, the general atmosphere is conducive to romance, you are strange and mysterious to her, her only impression of you is that you have made other women laugh [and aren't some shy guy hiding in the corner].  It's preselection at work.

 

She may see you as emotional, submissive, desperate, needy, single... un-alpha characteristics.  While men prefer their partners to be pure, virgins, women prefer studs, men already with multiple women.  Just seeing you with other women increases your SMV.  A shallow aspect of female psychology to be sure.   It works online too.   It's preselection again. 

You can do things to increase your sexual market value, work on controlling emotions, your conversational skills, acting assertively, appearing sociable, lifting weights.  All these things, practiced perfectly, will reduce your rate of rejection from maybe 90% to 70%.  And that's huge.

Edited by gamesguru, 14 June 2015 - 01:35 PM.

[Flex]

 

Have you tried coke? I believe Ritalin is "slow release" coke. Lasts all day. Coke lasts a few minutes. Coke is an SNDRI, not just a NDRI. Even St. Johns Wort is listed as a SNDRI! Which was why I was snappy and had a temper when I used it for years! This was a time when I lacked research and knowledge. I had serotonin syndrome. I got things done but I wasn't friendly. I was "wild" and easy to snap at anyone. I believe this was stereotypical behavior when one is on Ritalin and or coke. Actually one guy suspected I was on coke! It was St. John's Wort combined with SAMe and 5-htp!

 

ritalin doesnt feel anything like cocaine, nor amphetamine and the least anything to do with serotonin. its just some very dirty synthetic stimulant that never gave me a high and im shocked to hear some people get high on that crap.

 

 

lol this happens to me often. People suspect that I´m using Coke but I´m just slightly hypomanic sometimes and using here and then some noots & stuff.

Actually its quite annoying when everyone follows You on the toilet to chaught You in the act..

Womens think this even more, when I take e.g. amitryptiline. Interrestingly they become attracted because I look to them completly fearless (or something like that ?).

Dont ask me why, I´m actually anxious. This may sound weird but its actually the weird reality.
 

Edited by Flex, 14 June 2015 - 06:03 PM.

[Flex]

Regarding the Girl, be aware that Youre prone to emotions and that she is not empathic. So You should know with whom Youre dealing and the possible consequences.

I knew that the 2nd Girl would do stupid things, so I pretended that I still want her just to prevent her from doing stupid things like Drugs a few weeks ago.

The problem was and is that I´m very sensitive to this kind of feelings, so this destroyed me i.e. gave me anxiety, stress related impairments (little traumas so to say) and so on.

 

I tought that I could handle this but I couldnt. Be careful and keep care about Yourself because sometimes nobody does.

There are perhapsoptions to help her in other ways than just with a relationship. So You could find You one which is more suitable for You and she could get help.

Just my 2 cents

Edited by Flex, 14 June 2015 - 06:28 PM.

[OneScrewLoose]

Ritalin is not an amphetamine but it does affect serotonin.  However, like theanine, its unclear what is going on, but studies with conflicting results definitely show that ritalin is doing something with serotonin, either directly or indirectly, with transport or reuptake, etc.  Yeah we all know ritalin as a DNRI, but that doesn't mean its effects are actually restricted to dopamine and norepinephrine only.  Just consider bupropion.  Also, serotonin syndrome is a known risk in adderall overdose.  The bottom line is that we have a lot more to learn about the mechanisms of not just these drugs but most on the market.

 

Again, no. It has no affinity for the serotonin transporter. It might have some effect on the 5TH1a and 5HT2b receptors, but in vivo evidence is slim.

 

Serotonin syndrome is a theoretical risk of amphetamines, due to a minor affinity for the serotonin transporter, but this does not seem to apply in reality. This is why amphetamines (Adderall) and SSRIs are commonly prescribed together, even at quite high doses.

[eon]

Regarding the link you posted about; I don't have a facebook. The procedure therein is absurd. So some guy creates several fake female profiles to add as his "friends" to impress that he is getting attention so that way "real" women would notice the he is getting all the attention. It's a narcissistic move that women LOVE. 

 

I may need to lay off the Vyvanse since I think the dopamine release from it is making me feel the "love" I'll wait til everything cools off before I get back to using it again. I think I should be using propranolol for now to block out the norepinephrine release? It's a beta blocker that inhibits the amygdala so any negative emotions should be kept under control. 

 

She liked me before I even took Vyvanse about 2 months ago but her letting it be known she has the hots for me is as recent as when I started this thread. I'm not sure if the Vyvanse may have something to do with my body language having "confidence"? I have confidence and I do feel confident but the fact that she wanted to make things more awkward than it should be is what's creating these emotions. I know this is what she wants to create (awkwardness, confusion, emotions, etc.). Been there done that. With women, it's more of a "script" (tension, drama, suspense ala a bad chick flick) whereas with men it's to the point ala a good porn video (all the "tension" without the drama). LOL. 

 

 

 

 

I can't change how someone feels about me but when one has more important things to do, it would be nice to block out the emotions and get on with life. Even Stephen Hawking don't get women! 

 

True, especially if you've already made a bad first impression on the person, and been labeled as a friend for a period of many months. (read: forget this girl, plan for future successes)  Your chances with a random women at a bar or party are much better than one you've met at work, the gym or grocery store.  Alcohol is dis-inhibiting her, everyone is sociable, the general atmosphere is conducive to romance, you are strange and mysterious to her, her only impression of you is that you have made other women laugh [and aren't some shy guy hiding in the corner].  It's preselection at work.

 

She may see you as emotional, submissive, desperate, needy, single... un-alpha characteristics.  While men prefer their partners to be pure, virgins, women prefer studs, men already with multiple women.  Just seeing you with other women increases your SMV.  A shallow aspect of female psychology to be sure.   It works online too.   It's preselection again. 

You can do things to increase your sexual market value, work on controlling emotions, your conversational skills, acting assertively, appearing sociable, lifting weights.  All these things, practiced perfectly, will reduce your rate of rejection from maybe 90% to 70%.  And that's huge.

 

 

Edited by eon, 14 June 2015 - 09:46 PM.

[eon]

Vyvanse, Adderall, and Dexedrine were not listed as causing serotonin syndrome but methamphetamine can.The amphetamines are mostly NDRI, not SNDRI. I've never heard of anyone being prescribed Adderall with an SSRI when the amphetamine itself is an antidepressant. If anything it's the SSRI that will cause the serotonin syndrome!

 

 

Ritalin is not an amphetamine but it does affect serotonin.  However, like theanine, its unclear what is going on, but studies with conflicting results definitely show that ritalin is doing something with serotonin, either directly or indirectly, with transport or reuptake, etc.  Yeah we all know ritalin as a DNRI, but that doesn't mean its effects are actually restricted to dopamine and norepinephrine only.  Just consider bupropion.  Also, serotonin syndrome is a known risk in adderall overdose.  The bottom line is that we have a lot more to learn about the mechanisms of not just these drugs but most on the market.

 

Again, no. It has no affinity for the serotonin transporter. It might have some effect on the 5TH1a and 5HT2b receptors, but in vivo evidence is slim.

 

Serotonin syndrome is a theoretical risk of amphetamines, due to a minor affinity for the serotonin transporter, but this does not seem to apply in reality. This is why amphetamines (Adderall) and SSRIs are commonly prescribed together, even at quite high doses.

 

 

[eon]

I'm suspecting Vyvanse is what made me "appear" more confident but I don't know if the dopamine release is what's making me feel the love thing. Feeling confident may come across as "fearless". My doc told me I'm emotional at first meeting me and him had. Maybe I'm the problem here not the girl? She's just herself?

 

 

 

Have you tried coke? I believe Ritalin is "slow release" coke. Lasts all day. Coke lasts a few minutes. Coke is an SNDRI, not just a NDRI. Even St. Johns Wort is listed as a SNDRI! Which was why I was snappy and had a temper when I used it for years! This was a time when I lacked research and knowledge. I had serotonin syndrome. I got things done but I wasn't friendly. I was "wild" and easy to snap at anyone. I believe this was stereotypical behavior when one is on Ritalin and or coke. Actually one guy suspected I was on coke! It was St. John's Wort combined with SAMe and 5-htp!

 

ritalin doesnt feel anything like cocaine, nor amphetamine and the least anything to do with serotonin. its just some very dirty synthetic stimulant that never gave me a high and im shocked to hear some people get high on that crap.

 

 

lol this happens to me often. People suspect that I´m using Coke but I´m just slightly hypomanic sometimes and using here and then some noots & stuff.

Actually its quite annoying when everyone follows You on the toilet to chaught You in the act..

Womens think this even more, when I take e.g. amitryptiline. Interrestingly they become attracted because I look to them completly fearless (or something like that ?).

Dont ask me why, I´m actually anxious. This may sound weird but its actually the weird reality.
 

 

 

Edited by eon, 14 June 2015 - 10:02 PM.

[Duchykins]

 

 

Again, no. It has no affinity for the serotonin transporter. It might have some effect on the 5TH1a and 5HT2b receptors, but in vivo evidence is slim.

 

Serotonin syndrome is a theoretical risk of amphetamines, due to a minor affinity for the serotonin transporter, but this does not seem to apply in reality. This is why amphetamines (Adderall) and SSRIs are commonly prescribed together, even at quite high doses.

 

 

You misunderstood my meaning, and that could be my fault for not being clearer.  I wasn't talking about ritalin having an affinity for the transporter (by the way that's similar to what we used to say about bupropion and that turned out to be wrong), but that there is some effect on serotonin whether directly or indirectly which means something as simple as blocking the reuptake of dopamine and norepinephrine leading to an increase of these neurotransmitters, which could then in turn trigger alterations in serotonin (perhaps a decrease).  We know the brain loves to do stuff like this (increase one thing, decrease another, increase receptor density or decrease receptor density, etc) so it's not unreasonable to consider it.

 

Also, ritalin does have affinity for the transporter, it's just that it's very low. 

 

My point is simply that these two things, ritalin and serotonin, do have some kind of subtle relationship (I'm not implying an increase in serotonin necessarily), and we don't fully understand what it is yet.

 

But we're learning, albeit slowly.  There's odd stuff like this I found not too long ago: 

 

http://www.ncbi.nlm....les/PMC3770255/

http://www.ncbi.nlm....pubmed/26022000

 

I'm actually very anxious for more research into ritalin use in previously untreated adults and its long term effects on all the major neurotransmitters especially serotonin and GABA, partly because my doc put me on a trial of it recently and it's lightyears more effective and "cleaner" than adderall; so naturally, I want to keep taking it and am interested in mitigating potential decreases in either serotonin or GABA.

 

And you do have a valid point in serotonin syndrome being on the list of possible adderall side effects because of a theoretical risk from its subtle relationship with serotonin.

[Duchykins]

 

 I've never heard of anyone being prescribed Adderall with an SSRI when the amphetamine itself is an antidepressant. 

 

 

 

 

One of my docs wanted to me try an SSRI when he gave me an adderall script, maybe because I have a history of being very reactive to even slight changes in my serotonin levels; if it didn't trigger migraines then it would make me overly apathetic or irritable.  I said no because SSRIs scare me after one very bad reaction to Celexa nearly a decade ago.

 

Honestly, used to hear about that sort of thing all the time.  My little brother had ADHD and my mom was resistant to meds after reading for weeks, so I remember lots of arguments against adderall use in youth because so many of the same kids were additionally given SSRIs later (often a few years later) when they showed symptoms of depression.

 

I used to think adderall was the cause of the depression but I'm not so sure about that now since young people with ADHD are already prone to depressive tendencies due to the social cost of being an oddball at school.  The isolation, the judgment, the bullying, the difficulty in studies, poor grades... on and on.

 

I'm just saying it's not unheard of.

[eon]

OK I'm experimenting a bit by laying off Vyvanse and up my dose of lysine for the anxiolytic effect, just took 2 g of it. I still think my low dose Vyvanse is not a good dose since the confidence level only lasts about 2-3 hours, when I need this confidence all day long to block out all distractions. Does anyone here know if lysine would somewhat help banish serotonin syndrome? Look at the quote below:

 

"Lysine has a anxiolytic action through its effects on serotonin receptors in the intestinal tract, and is also hypothesized to reduce anxiety through serotonin regulation in the amygdala.^[40] One study on rats^[41] showed that overstimulation of the 5-HT4 receptors in the gut are associated with anxiety-induced intestinal pathology. Lysine, acting as a serotonin antagonist and therefore reducing the overactivity of these receptors, reduced signs of anxiety and anxiety-induced diarrhea in the sample population. Another study showed that lysine deficiency leads to a pathological increase in serotonin in the amygdala, a brain structure that is involved in emotional regulation and the stress response.^[40]Human studies have also shown correlations between reduced lysine intake and anxiety. A population-based study in Syria included 93 families whose diet is primarily grain-based and therefore likely to be deficient in lysine. Fortification of grains with lysine was shown to reduce markers of anxiety, including cortisol levels; Smiriga and colleagues hypothesized that anxiety reduction from lysine occurs through mechanism of serotonin alterations in the central amygdala; older primary research reports hypothesized lysine to reduce anxiety through the potentiation of benzodiazepine receptors (common targets of anxiolytic drugs such as Xanax and Ativan).^[42] (Note that all of these studies were funded by Ajinomoto, Co. Inc., an industrial manufacturer of lysine.)".

 

I know reserpine depletes serotonin and that's one of the natural remedies for it. I still wonder if anyone here know if any natural antipsychotics? Off topic I know but I'll ask on reddit. I don't feel I have serotonin syndrome now nor am I psychotic but the quote above seem like it's what I need right now to keep my emotions at bay considering serotonin is one of the responsible neurotransmitter when it comes to emotions, right?

 

Curious how many days must I wait for Vyvanse to be out of my system so I can try out some Kava Kava, which is to give me "serenity". I think it's what I need right now.

Edited by eon, 14 June 2015 - 10:50 PM.

[Flex]

This is what I´ve and others told, dopamine increases it and Cyproheptadine should afaik decrease it. It made at least me quiet robotic and dysphoric, amitryptiline too but a bit different.

watch/monitor Your self about the amphetamines, some people here have reported impairments even by using the recommened dose after a few months.

 

I found this somehow insightful from Dr. Mayim Bialik

Mayim Bialik (Amy Farrah Fowler) Explains a Different View of Big bang Theory

 

Confidence: In my case, confidence raises (and falls) depending on the peolple arround me. If they accept me and I´m able to "fit" in with my traits e.g. my pro-social behavior is appreciated or anything other of my personality,

I become confident. I can of course be confident in other "enviroments" but this is not allways stable because of my various impairments and my hystory.

I think confidence is not a black box, neither something that You can just pick it up. I think it comes from a different direction than its often suggested.

You can try the alpha/omega thing: kick Youself in Your ass, dont be a sissy, You can do everything if You just want it. This is just suitable to certain things not to all.

but those guys who I met, were unsecure in their inner core, altough the womens liked it. (wonderful blue pill)

 

I use different tricks to trick my self: When falling in front of others, I tend to explain my self how this happens & etc. so to force me into analytical thinking and therefore to dissociate from my feeling of embarrasment.

It works, admittely its not the best solution but an option.

Whereas most others tend to mask it and surpress their own feeling (and the other few, dont know)

You can see on the Streets how the people tick, those with nice cars (but high depts), are coupling their confidence on the reflection/reatction of the people. though its not allways about confidence

 

One could think experimetically whether its possible and how to couple/encouple his confidence, auxiliary, on things or other unless it leads to something similair like depersonalisation like in my case..

So in my case, I´m just my self too. Since the majority is different, I have to cope/adapt but also be integer, I have tried to change me but it didnt worked and didnt had any sence at the end of the day i.e. beeing someone else.

Its rather better to find new sides in You that were allready there and by intergrating the new and/or the old ones successfuly in Your enviroment, it "should" raise You confidence

otherwise one could be on the wrong place like a Polarbear in the Jungle.

 

 

Edited by Flex, 14 June 2015 - 11:37 PM.

[Duchykins]

OK I'm experimenting a bit by laying off Vyvanse and up my dose of lysine for the anxiolytic effect, just took 2 g of it. I still think my low dose Vyvanse is not a good dose since the confidence level only lasts about 2-3 hours, when I need this confidence all day long to block out all distractions. Does anyone here know if lysine would somewhat help banish serotonin syndrome? Look at the quote below:

 

"Lysine has a anxiolytic action through its effects on serotonin receptors in the intestinal tract, and is also hypothesized to reduce anxiety through serotonin regulation in the amygdala.^[40] One study on rats^[41] showed that overstimulation of the 5-HT4 receptors in the gut are associated with anxiety-induced intestinal pathology. Lysine, acting as a serotonin antagonist and therefore reducing the overactivity of these receptors, reduced signs of anxiety and anxiety-induced diarrhea in the sample population. Another study showed that lysine deficiency leads to a pathological increase in serotonin in the amygdala, a brain structure that is involved in emotional regulation and the stress response.^[40]Human studies have also shown correlations between reduced lysine intake and anxiety. A population-based study in Syria included 93 families whose diet is primarily grain-based and therefore likely to be deficient in lysine. Fortification of grains with lysine was shown to reduce markers of anxiety, including cortisol levels; Smiriga and colleagues hypothesized that anxiety reduction from lysine occurs through mechanism of serotonin alterations in the central amygdala; older primary research reports hypothesized lysine to reduce anxiety through the potentiation of benzodiazepine receptors (common targets of anxiolytic drugs such as Xanax and Ativan).^[42] (Note that all of these studies were funded by Ajinomoto, Co. Inc., an industrial manufacturer of lysine.)".

 

I know reserpine depletes serotonin and that's one of the natural remedies for it. I still wonder if anyone here know if any natural antipsychotics? Off topic I know but I'll ask on reddit. I don't feel I have serotonin syndrome now nor am I psychotic but the quote above seem like it's what I need right now to keep my emotions at bay considering serotonin is one of the responsible neurotransmitter when it comes to emotions, right?

 

Curious how many days must I wait for Vyvanse to be out of my system so I can try out some Kava Kava, which is to give me "serenity". I think it's what I need right now.

 

I take lysine cyclically to stabilize my serotonin and prevent migraine.

 

If you really think you have serotonin syndrome, stop taking shit.  Especially lysine since one of its off-uses is as a migraine abortive (injection) -- similar to a triptan which floods the brain with serotonin and triggers vasoconstriction (among other things) which kills the pain of migraine.  During the migraine the person loses a lot of serotonin through the urine and this is related to the uncontrolled vasodilation in the brain; typically, restoring serotonin interrupts the attack.  I'm not saying that is what lysine does in the brain, but I can tell you that if lysine decreased or blocked serotonin in the brain like you seem to think it does then it would only exacerbate a migraine instead of killing it.

 

If you really think you have serotonin syndrome, go to the hospital.  I have seen a real episode of serotonin syndrome and it nearly killed this woman (she was abusing tramadol).  She was standing in her kitchen when she had a seizure and hit her head on the counter on her way to the floor.  She cracked her skull and started spurting blood from her ears and began leaking CSF from one of the ears and she continued to seize for some time.  It was scary bloody shit.  She's only alive because she wasn't alone when it happened and was airlifted to a special trauma ER in time.  

 

Stop fucking around.

Edited by Duchykins, 15 June 2015 - 03:04 AM.

[eon]

What do you guys think of NAC (n-acetyl cysteine), see below:

Psychiatry

Acetylcysteine has been successfully tried as a treatment for a number of psychiatric disorders.^[35][36][37] In particular, as a treatment for schizophrenia, bipolar disorder, depression, trichotillomania, skin picking, autism, obsessive-compulsive disorder, drug (including nicotine, cannabis, methamphetamine, cocaine, etc.) and gambling addiction.^[35][38][39]

Acetylcysteine has also been hypothesized to exert beneficial effects through its modulation of glutamate and dopamine neurotransmission as well as its antioxidant properties.^[40]NAC has also been trialled with some efficacy in people with Alzheimer disease.^[35]

 

It's also known as a detoxifying agent. Could NAC drive out the amphetamine faster? Could it helping with addiction mean it could work not falling for someone's "like" or "love" for me since it is a form of addiction? Considering it is said to be potent for OCD, I feel as if my Vyvanse use have made me obsessed over the girl that liked me, LOL. Despite the OCD wasn't that bad when on Vyvanse. I'm aware that OCD can be a symptom when on an amphetamine. 

 

I think amphetamines are wonderful only when you are working on calculus or chemistry but when you're around people, especially if they like you, it puts you in an awkward position, IMO.

 

Edited by eon, 15 June 2015 - 03:03 AM.

[Duchykins]

If you're trying to "drive out the amphetamine faster" you're not going to do it.  Addicts have long been looking for ways to get clean quick to pass drug tests and the only thing that's somewhat reliable is guzzling fluids.  Not that it actually gets the drug out faster, it just dilutes urine and makes the drug less detectable.

 

Honestly, you are being ridiculous with all of this, and if I take you at your word that you are serious about this, then I'm becoming very concerned as to your health, both physical and mental.

[eon]

Oh I know! That's why at the start of the thread I mentioned something about the "love thing" can be bad for you, etc. That's why I'm here trying to figure this all out. I'm thinking it's the Vyvanse at work. As I mentioned my dose is only 30 mg. I would think it's too low which is why I'm still distracted? Could be the dopamine rush that's making me "fall for it". My doc asked me, prior to getting prescribed Vyvanse, if I have a girlfriend I said no. The tone of his question seem to imply that one needs to have a lover to be on amphetamines as to not get distracted by temptations or feeling "cuddly" as I have been feeling. 

 

If you're trying to "drive out the amphetamine faster" you're not going to do it.  Addicts have long been looking for ways to get clean quick to pass drug tests and the only thing that's somewhat reliable is guzzling fluids.  Not that it actually gets the drug out faster, it just dilutes urine and makes the drug less detectable.

 

Honestly, you are being ridiculous with all of this, and if I take you at your word that you are serious about this, then I'm becoming very concerned as to your health, both physical and mental.

 

Edited by eon, 15 June 2015 - 05:16 AM.

[eon]

Maybe I should change to Dexedrine? Maybe the slow release Vyvanse is making me feel such way? Vyvanse is a completely different molecule from what I understand but still turns into dextroamphetamine (ala Dexedrine). I think its indirect mechanism is the issue here?

[Mind_Paralysis]

You're in the US, yes? Well, I think the best thing to do here then, is to completely drop the amphetamines.

 

Instead, try DEXmethylphenidate - FOCALIN! : D It is the single-most subtle in-use stimulant around, and it gives the least euphoria, or ANY other effect than focus, even, of the prescribed stimulants.

 

Now, you will still feel some of the psychomotor BS, but it will be far less than with ritalin or Vyvanse.

Also, combine it with Intuniv - it enhances your prefrontal cortex, and should give you better self-control - it could help you to do more CBT to control your emotions.

 

 

So: Focalin + Intuniv = possible success in emotion-control.

[drg]

These are all the dumbest ideas I have ever heard

Take heroin and forget about her

or develop some self control

[drg]

Maybe something to give you limp dick could help too

[Duchykins]

Could be the dopamine rush that's making me "fall for it". My doc asked me, prior to getting prescribed Vyvanse, if I have a girlfriend I said no. The tone of his question seem to imply that one needs to have a lover to be on amphetamines as to not get distracted by temptations or feeling "cuddly" as I have been feeling. 

 

 

No offense to you or your doc, but that is absurd.

 

You cannot place the blame of an infatuation at the feet of any modern drug.  Lust & love are the oldest drugs.  New love is nearly always described as a type of madness in anything written in human history.

 

Also, dopamine is not typically responsible for "cuddly" feelings.

 

You are additionally going with the old paradigm that dopamine is the pleasure neurotransmitter & that dopamine-related issues are responsible for addictive behaviors.  Even though we now know that's not true because brain chemistry is not that simple; serotonin, norepinephrine, GABA, oxytocin, acetylcholine, histamine, glutamate, etc are also major players in pleasure, this bullshit about dopamine refuses to die, but it's not that surprising given how much bullshit lingers in the medical professions partly because doctors are just people who, like anyone else, get a bit set in their ways and can't be expected to know all the new shit we discover after they complete their training.

 

I cannot help but to think of this in terms of what I know about human evolution and sexual selection (I'm a bioscience major with emphasis on evolution and ecology as opposed to biochemistry, etc).  Human attraction is pretty complicated due to our prodigious frontal lobe development, but still operates within the framework of basic mammalian physiology.  Well what does this mean?  There are all kinds of subtle but strongly influential factors in play here that most people aren't aware of, like scent (people that don't smell attractive to us tend to be genetically incompatible or at least not-optimal).  Scent perhaps tends to be a more decisive factor for females when regarding males, but men can tell by scent when a woman is ovulating even though they're not conscious of it (this triggers an increase in testosterone in men, making her seem "more attractive" when in fertile peak of her cycle).  Don't get me wrong though, that's not the only time men find women's scent intoxicating.

 

And that's just one little piece of this ridiculously complex puzzle, and it is something that is in play here with you, but seriously to go on about it the others would take hours of typing on my part so I'll just stop there.

 

That all being said (and I can't believe I'm about to participate in your insane quest), maybe you could experiment with bombarding yourself with serotonin and/or acetylcholine (without killing yourself) to see if you can reach the place of apathy or anhedonia that are notorious side effects of drugs that affect those transmitters.  Then see how much you continue to obsess about her.  

 

I'm betting it won't work because you're stuck on this woman for stronger reasons than you think--maybe not all of them animalistic and biochemical, maybe some of them intellectual.  You're not exactly in an objective position here to judge why you're so interested in her.

 

You haven't also considered the possibility that the Vynase may actually be helping you.  Longing for companionship, love, forming a deep bond with someone, all that crap is normal, healthy, social mammalian behavior in humans.  Maybe you are more capable of doing this with another human being because you are being effectively treated, and this just never happened to you before to where you're actually happy?    I'm just saying it's possible.

Edited by Duchykins, 15 June 2015 - 07:46 PM.

[Ark]

Take Naridil... For the fix! Warning (Note:research before taking)

[OneScrewLoose]

Take Naridil... For the fix! Warning (Note:research before taking)

 

I heard Nardil, pickles and aged cheese is a great combo for forgetting love. It makes your heart beat so fast, the increased heart rate from the girl seems minute in comparison, and this cures you of the infatuation.

[HappyShoe]

This whole post is evidence you shouldn't be around women. You're going to really screw with that poor girl's heart. Either suck it up and live your life, and let yourself love, or be alone. There is no in between, and to attempt to do so, when you know you don't want to, is not only irresponsible, but is immoral. Btw, all these drugs are going to have consequences, so if you think you have problems now, enjoy what comes next. Amphetamines cause massive downregulation and adrenal problems, can induce anxiety disorders in some people, as well as other great stuff. Even if used responsibly it's similar to a few month meth binge after a few years of semi-frequent weekly amphetamine usage, even at prescribed dosage. SSRIs can cause all sorts of great stuff like suicidal ideation, sexual dysfunction, dysphoria, impotence, etc.

Someone had said learn some self control, and I agree.

Or ignore it, and be a slave to drugs your whole life instead of the master of yourself. Which would you prefer?

The people here generally want to use things as medicine to be better versions of themselves, or to cure/treat real illnesses. You're trying to lobotomize yourself, what are you thinking?

This may seem rude, but it's intended to snap you out of it and give you some perspective for your own good.