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Any Success Stories?

brain fog herbs cognition vitamins

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#1 Blackkzeus

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Posted 30 September 2015 - 05:00 AM


Anybody struggle with brain fog, lethargy, memory loss, cognitive impairment, adhd, depression, etc. and has seen  improvement with natural supplements such as vitamins, minerals, and herbs? I've been struggling with crippling brain fog, anhedonia, and fatigue for quite some time now and have been trying to solve these issues for almost 3 years now. I haven't see much improvement with my baseline cognitive abilities. Of course certain nootropics and stimulants temporarily alleviate some of  the cognitive issues but of course I'm more interested in something long term.So whoever has struggled with brain fog please list some supplements and things you did that returned you cognition and memory to it's natural basline



#2 lostfalco

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Posted 30 September 2015 - 04:46 PM

You may already be familiar with this study...but here is a study conducted using a multi-pronged approach to treat cognitive dysfunction in 30 former NFL players. Might be worth a try if nothing else has seemed to work so far. =)

 

Also, check out Joe Cohen's info over at selfhacked. http://selfhacked.co...e-of-brain-fog/

 

http://www.ncbi.nlm....pubmed/21615001

 

J Psychoactive Drugs. 2011 Jan-Mar;43(1):1-5. doi: 10.1080/02791072.2011.566489.

Reversing brain damage in former NFL players: implications for traumatic brain injury and substance abuse rehabilitation.
Abstract

Brain injuries are common in professional American football players. Finding effective rehabilitation strategies can have widespread implications not only for retired players but also for patients with traumatic brain injury and substance abuse problems. An open label pragmatic clinical intervention was conducted in an outpatient neuropsychiatric clinic with 30 retired NFL players who demonstrated brain damage and cognitive impairment. The study included weight loss (if appropriate); fish oil (5.6 grams a day); a high-potency multiple vitamin; and a formulated brain enhancement supplement that included nutrients to enhance blood flow (ginkgo and vinpocetine), acetylcholine (acetyl-l-carnitine and huperzine A), and antioxidant activity (alpha-lipoic acid and n-acetyl-cysteine). The trial average was six months. Outcome measures were Microcog Assessment of Cognitive Functioning and brain SPECT imaging. In the retest situation, corrected for practice effect, there were statistically significant increases in scores of attention, memory, reasoning, information processing speed and accuracy on the Microcog. The brain SPECT scans, as a group, showed increased brain perfusion, especially in the prefrontal cortex, parietal lobes, occipital lobes, anterior cingulate gyrus and cerebellum. This study demonstrates that cognitive and cerebral blood flow improvements are possible in this group with multiple interventions.

 

Extended quotes from the study (since it's paywalled =)):

"All subjects were offered the opportunity to participate in a pragmatic interventional phase. Pragmatic interventions are ones that participants might experience in a “real-world” clinical situation. The interventions included education on a brain-healthy lifestyle, such as proper nutrition, regular exercise, limiting alcohol, eliminating drug abuse and cigarette smoking, getting appropriate sleep, and having sleep apnea assessed if symptoms were endorsed. As obesity has been associated with dementia and a smaller brain (Raji et al. 2010), we encouraged overweight or obese players to lose weight. Forty-eight percent of players in the initial study were overweight or obese, even taking into account their large body frames. Author KW ran an optional weight-loss group for players. In addition, players were given 5.6 grams of fish oil a day, containing 1720mg of EPA and 1160mg of DHA, as omega-three fatty acid supplementation has shown benefits with memory, mood and cognition (Michael-Titus 2009Conklin et al. 2007) and a high-potency multiple vitamin, which has been shown to enhance mental performance (Kennedy et al. 2010). Participants in the interventional study also received a brain enhancement supplement that contained clinically effective dosages of nutrients to enhance blood flow: ginkgo (Santos et al. 2003) and vinpocetine (Gulyás et al. 2002); decrease cortisol: phosphatidylserine (Monteleone et al. 1990); enhance acetylcholine: acetyl-l-carnitine (Jones, McDonald & Borum 2010) and huperzine A (Zhang, Yan & Tang 2008); and enhance antioxidants: alpha-lipoic acid (Arguelles et al. 2010) and n-acetyl-cysteine (Dodd et al. 2008). The trial for each participant ranged from two to 12 months, with the average being six months, depending on the participant's ability to travel to the study location in Southern California."

 

"In the retest situation, corrected for practice effect, there were statistically significant increases in MACF scores in general cognitive functioning, general cognitive proficiency, attention, memory, reasoning, information processing speed and accuracy (see Table 1). There were also increases in spatial processing and reaction time, although these were not statistically significant. Many of the participants had robust increases in performance. Table 1 also lists the number of participants in each category who had a greater than 50% increase in percentile scores."

 

"This clinical study targeted retired professional football players who had experienced traumatic brain injuries as a result of numerous impacts over extended periods of time. Our goal was to design an interventional strategy that would improve cognitive function by enhancing cerebral blood flow, acetylcholine and antioxidant activity. We utilized a standard brain imaging tool (SPECT) and a standard computerized neuropsychological test (MACF) to determine if improvement could be obtained. Our findings on this unique population are encouraging as we observed significant improvements in general cognitive functioning, information processing speed, attention and memory in close to half of the participants. Plus, there were significant increases in regional cerebral blood flow seen on SPECT."

 

"This clinical study is limited by its nonrandomized, open-label, multifaceted design and the results must be interpreted with caution. Our hope is to use this trial as a starting point to more rigorously study the individual parts of the treatment protocol and to extend the study to include other types of brain damage, including blast injuries, single-incident brain traumas, and those resulting from substance abuse."

 

 

 

 



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#3 gamesguru

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Posted 04 October 2015 - 01:05 AM

multi-pronged approach to treat cognitive dysfunction in 30 former NFL players. Might be worth a try

Also, check out Joe Cohen's info over at selfhacked. http://selfhacked.co...e-of-brain-fog/

 

 

Reversing brain damage in former NFL players: implications for traumatic brain injury and substance abuse rehabilitation.

Brain injuries are common in professional American football players. Finding effective rehabilitation strategies can have widespread implications not only for retired players but also for patients with traumatic brain injury and substance abuse problems. An open label pragmatic clinical intervention was conducted in an outpatient neuropsychiatric clinic with 30 retired NFL players who demonstrated brain damage and cognitive impairment. The study included weight loss (if appropriate); fish oil (5.6 grams a day: 1720mg of EPA and 1160mg of DHA,); a high-potency multiple vitamin; and a formulated brain enhancement supplement that included nutrients to enhance blood flow (ginkgo and vinpocetine), acetylcholine (acetyl-l-carnitine and huperzine A), and antioxidant activity (alpha-lipoic acid and n-acetyl-cysteine). The trial average was six months. Outcome measures were Microcog Assessment of Cognitive Functioning and brain SPECT imaging. In the retest situation, corrected for practice effect, there were statistically significant increases in scores of attention, memory, reasoning, information processing speed and accuracy on the Microcog. The brain SPECT scans, as a group, showed increased brain perfusion, especially in the prefrontal cortex, parietal lobes, occipital lobes, anterior cingulate gyrus and cerebellum. This study demonstrates that cognitive and cerebral blood flow improvements are possible in this group with multiple interventions.

 

Not sure about long-term supplementing of the red stuff, but looks otherwise solid.  I recommend flax and hemp to displace some of the fish oil, and some whole fish.

  • Bacopa improved memory recall and attention, and to a lesser degree, depression and anxiety.
  • Green tea seems to worsen anxiety, but is otherwise helpful.
  • I don't use ginkgo very regularly, but still it's improved attention and clarity.
  • Exercise makes me a little restless (probably due to NMDAR[1]), but is otherwise helpful.

I don't have big problems with "brain fog, lethargy, memory loss, cognitive impairment", but ALCAR boosts NGF.   And check out redan's post: http://www.longecity...-increase-bdnf/



#4 ceridwen

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Posted 04 October 2015 - 01:38 AM

Wonderful news

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#5 baccheion

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Posted 27 November 2015 - 01:49 AM

(things to look into, not to take all at once:) Cerebrolysin, DXM, memantine, IDRA-21 (1mg/kg once or twice was said to repair Xanax induced fog, though at that dosage you may have strong side effects), noopept, acetyl l-carnitine, etc.

 

I'd say down a bottle of pure DXM (research well before considering), supplement with memantine (10mg should be enough. Begin at 5mg, then move to 10mg 4 days later.) + IDRA-21 (1mg/kg the first time if the side effects didn't manifest at a lower dosage, 0.1mg/kg thereafter) for a week or 2, then do a cycle of Cerebrolysin every quarter. When not on a Cerebrolysin cycle take N-Acetyl Semax Amidate.


  • Dangerous, Irresponsible x 1





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