5 replies to this topic

[shifter]

I'm not talking about people who 'think' it looks less on 'maybe' x' supplement' I'm wondering if people have managed a very clear reduction or elimination in age spots without using a laser. It can be by a cream, supplements or both. What has worked?

Anyone?

[mikey]

Topical niacinamide spray.

 

I've noticed a difference. Therefore, I continue to apply it occasionally.

 

http://www.ncbi.nlm....les/PMC3142702/

 

[aconita]

Chemical peelings do work very well but need caution and a bit of expertise.

 

TCA 30-50% applied to the spots will erase them immediately but adverse reactions might happen, full face TCA peeling at 25-35% is effective but might not erase all spots (some seem harder than others to wipe out).

 

TCA at those concentrations might leave scares, especially if no chemical peel has ever been performed before, glycolic acid peelings are not very effective by themselves (at least in the immediate) but do "condition" the skin to better cope with subsequent stronger acids, more than 35% is worthless in my experience, it only causes more irritation without being more effective.

 

A safer compound is glycolic acid 20-25% mix with cogic acid 1-2% to be used just on the spots, it is quite aggressive but more predictable and "easier" than TCA, same efficacy in my experience and definitely preferable.

 

For whole face treatments with glycolic-cogic acid I would suggest caution, spot test before and a smart idea would be to play it safe first (10%+1%), I never did that yet.

 

Malic acid < 10% + cogic 1-2% should work well, glycolic+malic+cogic should as well, personally never tried those mix yet. 

 

Any of the above in a hyaluronic gel base would be easier to apply (doesn't run) and attenuate some of the irritation, I did only 1.5% hyaluronic acid gel + glycolic 10-15% full face everyday, nice and good peelings, not effective for "harder to erase" spots in the short term (30 days or so) but nice for general better looking skin, I prefer it by far to once a week 35% glycolic only, it doesn't need buffering afterward. 

 

I am using 1.5 % hyaluronic acid gel + 4% niacinamide right now but is too early to report definitive results, so far I like it.

 

Dermarolling might work up to a certain degree but is much slower.

 

The glycolic + cogic gives immediate results if you don't mind some scabs for a few days.

[linlin92]

I find using niacinamide alone is boring and it won't make an impact on skin the way L-ascorbic acid (vitamin C), retinoids or peels do but over months it does help smooth out fine lines and brighter skin tone. It has reduced breakouts and shade of a birthmark (in my case), but then I didn't use just niacinamide. I'm a multi-angle attack mode kind of gal.

 

Just remember to check your face a few minutes after applying to make sure no white residue marks remain

[cuprous]

A few different people taking c60oo have reported improved skin and faded spots.  This is a powerful supplement with a track record of only a few years so do your own research.

[treonsverdery]

the studies say different things about centrophenoxine, a nootropic. https://www.ncbi.nlm...xine lipofuscin