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Fixing High Blood Pressure - Really/No BS

hyperetension

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#1 eighthman

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Posted 16 July 2016 - 04:45 PM


I offer this post out of a sense of deep frustration in regard to treating my hypertension.  With aging, it has crept up on me without respite.

 

You name it, I've tried it : magnesium, meditation, pomegranate, hawthorn, qi gong,  synced heartbeat music and much more.  Nothing really works and my doctor keeps uping my dosage of "prils" and Thiazides.

 

However, one thing has worked (finally!) to reduce my blood pressure to mostly normal. I went on a low carb diet and reduced my weight from 184 down to 169 (I'm 5' 10').   I understand that low carb diets can reduce hypertension for reasons not completely understood.

 

I offer no medical advice just my own repeated experience about high blood pressure rising and falling oddly relative to about 10 lbs.  Since I'm fairly thin to begin with, people ask why I'm on a lowcarb diet.   It just seems effective and I don't know why but thought I would share this oddity with others who may be stuck.


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#2 aconita

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Posted 20 July 2016 - 09:00 PM

Did you try mixing table salt and potassium bicarbonate 50/50?



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#3 PeaceAndProsperity

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Posted 22 July 2016 - 08:08 PM

Linus Paulin therapy works, as I posted in another thread. Works for almost all. If it doesn't work, it's not due to plaque build up but due to calcified arteries, nitric oxide deficiency or excessive blood coagulation, but these things are rarer on the long-term.

 

Proline, lysine (main component) and vitamin C. Doesn't matter if you're 90 or 70 or whatever, it works.


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#4 pamojja

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Posted 23 July 2016 - 12:47 PM

 

You name it, I've tried it : magnesium, meditation, pomegranate, hawthorn, ...

 

Have you tested for magnesium deficiency. Best done with an RBC test. Personally made the experience with a apparently very severe Mg deficiency, that it isn't overcome that easily with oral supplementation. I upped my dose of daily elemental Mg to now 2.2 g/d over many years. All it prevented were painful muscle-cramps, blood tests still show severe deficiency.


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#5 Darryl

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Posted 03 September 2016 - 08:15 PM

While I believe fasting is probably the best way to deal with non-responsive hypertension, I thought this trial with low-doses of OTC cough suppressant dextromethorphan is worth a try:

 

Yin et al, 2016. Combination with low-dose dextromethorphan improves the effect of amlodipine monotherapy in clinical hypertension; a first-in-human, concept-proven, prospective, dose-escalation, multicenter studyMedicine95(12), p.e3234.

 

This was a prospective, 14-week, dose-escalation, multicenter study. After 2-week run-in period with AM 5 mg/day, hypertensive patients who got the BP goal of 140/90 mmHg kept receiving AM monotherapy for another 12 weeks. The nonresponders, while kept on AM 5 mg/day, received additional DXM treatment for 3 sequential dose-titrated periods with initially 2.5 mg/day, followed by 7.5 mg/day, and finally 30 mg/day. Each period was for 4 weeks. The patients at BP goal after each treatment period were defined as the responders and kept on the same combination till the end of the study. The responder rate of each treatment period was recorded. The changes of BP and serum antioxidant/endothelial markers between week 14 and week 2 were evaluated.

 
Of the 103 patients initially enrolled, 89 entered the treatment period. In the 78 patients completing the study, 31 (40%) at BP goal after 2-week AM run-in kept on AM monotherapy (DXM0). The addition of 2.5 (DXM2.5) and 7.5 mg/day (DXM7.5) of DXM enabled BP goal achievement in 22 (47%) nonresponders to AM monotherapy including 16 (29%) with DXM2.5 and 6 (18%) with DXM7.5. Only 4 patients (16%) reached BP goal with the combination of DXM 30 mg/day (DXM30). Overall, 73% of the 78 patients reached BP goal at the end of the 14-week study. Mean systolic BP was reduced by 7.9% ± 7.0% with DXM2.5 (P < 0.001) and by 5.4% ± 2.4% with DXM7.5 (P = 0.003) respectively at week 14 from that at week 2, which was unchanged in either DXM0 or DXM30 group.

 

 
 
Low-dose DXM is a fascinating compound for those interested in inhibiting NADPH oxidases, the primary extracellular source of reactive species, and a major mediator of hypertension.
 
 
 





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