So im interested to know how saint johns wort effects the hpa axis and thus cortisol production. Im suffering from low cortisol at the moment and im trying to find good remedies for it.
In theory hyperforin should upregulate the 5ht1a and 5ht2a receptors which both, when activated, should increase acth.
has anyone taken it for downregulated hpa axis - and had succes with it?