Yeah, I've been looking into what the h*ll causes this, and this is the only plausible explanation I can find:
Norepinephrine must be SELECTIVE towards the Alpha-2-receptors - hence, an increase in NE-tone hits the Alpha-2's FIRST - meaning that very quickly, any NRI-agent will actually COUNTERACT itself, since Alpha-2-receptors are auto-receptors - increasing acitivity on them, signals the brain that there's too much NE, hence the brain over-reacts and lowers NE-output DRAMATICALLY.
Hence why I'm currently feeling so lethargic, and as if every single symptom of burnout and SCT is amplified HUNDREDFOLD while taking ATX.
But is this all caused by low blood-pressure, as I believe this is a result of Alpha-2-agonism? I've already got a naturally very, VERY low blood-pressure - I once fainted as a teenager, because my blood-pressure was so low.
If this is true, that sedation from ATX is caused by low blood-pressure, then how do I raise it? And SHOULD I raise it? I've actually tried Clonidine for my sleeping-issues, and now that I recall... the feeling was actually similar!
Caffeine is the only blood-pressure increasing agent currently legally available in my area - should I start micro-dosing that? On the other hand, it will merely give me a small spike, and then that's that - back even lower into sedation!
Modafinil, I am convinced, could deal with this problem in NO-TIME! However, it's not legal in my jurisdiction, so that'll be a loong, looong time in the coming...
What do you think lads and lass's? Is ATX sedation solved by merely increasing blood-pressure? But what about the lowered NE-tone? Wouldn't I still be left with worsened attention then? Blood-pressure can, as you all know, go up in different way - not necessarily in a way that increases NE-tone in the SPL.
I'm a bit stumped by this... especially by the fact that I feel both sedated and stimulated at the same time! I've felt unable to watch any video or play any game all day - could hardly even go grocery-shopping, and I find myself unable to feed myself, since cooking is out of the question - HOWEVER...!
I just realized that my typing is at DOUBLE the usual speed! Verbal memory seems to be enhanced as well, the words flow like WATER! 0_o
How is this possible if my overall NE-tone is so low?? God-damnit! I just don't understand ATX... the pharmacokinetics are like nothing I have ever seen or felt...
Any advice heartily received.