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Looking to heal brain after years of ketamine use. Any recommendations?

nootropics nmda receptor

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#1 pipe_49

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Posted 17 February 2017 - 03:26 AM


For the past 4 years, I have used and enjoyed ketamine on a weekly basis. However, after 4 years of use, my tolerance is skyhigh and I enjoy almost no subjective effects anymore. Basically, it does almost nothing now except make me feel a bit numb. I've realized its time to put ketamine, and other drugs, on hold. To be honest, it frightens me a bit that it has no effect at all anymore, because I figure it must have made some structural changes to my brain. I'm joining longecity in hopes of determining what those changes are and how to reverse them. I don't notice any difference in my mental health when sober, but I figure there must be some sort of change if there has been a structural change to my brain. Further, the damage may have accumulated slowly enough that I didn't notice the changes as they occurred. 

 

I've decided to go on at least a 3 month break from all drugs to give my brain some rest and healing time. If possible, I want to accelerate or assist that healing through use of nootropics. Unfortunately, I'm not sure where to start. I know that ketamine is an NMDA receptor antagonist, so I imagine that for some reason, my NMDA receptors are no longer being antagonised (inhibited) by ketamine. I guess what I need to do is restore my NMDA receptor's ability to be antagonised. I don't want to do this so much so that I can feel ketamine again, but more so to reverse whatever damage was done to my brain so that I can operate at full function. In my normal every day life, I don't notice any different mental effect caused by the changes to my NMDA receptors, but I figure there must be some change. I want to reverse any damage, if possible.

 

Any suggestions for nootropics that could help heal the damage, or any information on what damage may exist, would be appreciated!







Also tagged with one or more of these keywords: nootropics, nmda receptor

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