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Siberian Fir extract - Heat shock genes and restoring gene expression in senescent cells?

siberian fir heat shock senescent

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#1 Kirito

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Posted 01 March 2017 - 05:22 PM


"Treatment with Siberian fir terpenoids coincided with an increase in the expression of heat shock genes (the cell's mechanism of response to elevated temperatures) by a factor of 1.5 to three. These genes play a major role in the assembly, folding and transport of complex proteins, as well as in degrading and recycling unneeded proteins. By analyzing cell pathways induced by Abisil treatment and other cellular mechanisms involved in the experiment, the scientists concluded that the drug is capable of restoring gene expression in senescent cells to the level of younger cells."

 

https://medicalxpres...properties.html


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#2 Logic

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Posted 01 March 2017 - 10:53 PM

Considering the study (flies) linking HSP decrease to programmed aging, you would think this and other HSP upregulators would get more attention.

Thx Kirito.



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