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"Most Potent Longevity-Extending Pharmacological Compound Intervention Ever Described in Scientific Literature"


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#1 mccm98

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Posted 21 March 2017 - 07:17 PM


Science Alert Write Up:
http://www.scienceal...low-down-ageing


Journal Article:
http://www.impactjou...65&path[]=22203

"“In total, we found six new groups of molecules that decelerate the chronological ageing of yeast,” said biologist Vladimir Titorenko from Concordia University.

As the authors report in Oncotarget, one of these compounds – a specific extract of willow bark (Salix alba) – is the most potent longevity-extending pharmacological intervention ever described in scientific literature. In testing, the willow bark extract increased the average chronological lifespan of yeast by 475 percent and the maximum chronological lifespan by 369 percent.

If these findings can be replicated in something other than yeast, it’s a major discovery, outperforming the anti-ageing effects of both rapamycin and metformin. And in addition to slowing ageing, the compounds may also have beneficial effects on cellular processes when it comes to preventing related diseases, such as cancer, the researchers say. The other extracts come from Cimicifuga racemosa, Valeriana officinalis L., Passiflora incarnata L., Ginkgo biloba,and Apium graveolens L.."

This would seem to support the idea that aspirin is a potent anti aging drug considering it is derived from Willow Bark.

Thoughts?
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#2 Exception

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Posted 22 March 2017 - 10:04 PM

I agree that aspirin is a geroprotector. I've seen a few studies showing that it increases lifespan in worms and flies and it is known to reduce platelet aggregation.

 

This is certainly intriguing, but if this is the first study on these extracts, I wouldn't get too excited until they're replicated in an animal model.


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#3 Turnbuckle

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Posted 22 March 2017 - 10:48 PM

This paper has already been discussed on a couple of threads, in particular this one.



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#4 nickdino

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Posted 24 March 2017 - 07:12 AM

In testing, the willow bark extract increased the average chronological lifespan of yeast by 475 percent and the maximum chronological lifespan by 369 percent.

How does that work? Shouldnt those numbers be swapped?




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