38 replies to this topic

[Diamondz]

Although I concur with your observations; I know exercise, meditation, and supplements are only promote so much response. Of course they are effective, and tend to be more effective if you're already healthy, or have severe defect.

 

At the age of 17-19, I ran a lot, worked out in my room, reduced food consumption, meditation, and used dual-n-back. I would take 1 hour run on my sub-division towards the evening around 10PM. I was hallucinogenic, when complete I could feel my body rush with blood circulation, my brain felt good, and was more apt when home.

 

Pharmacology can elicit biological response not native, and many of the drugs I've used promote response I would not otherwise have. I've had very profound experience without them, but I understand I can provoke activation when wanted with drugs.

 

Dopamine agonism is the wrong way to go, unless you have parkinsons.

Go for the root cause.

Psychological problems causing it perhaps?

Exercise+Meditation, and supplements that induce potent neurogenesis will do far more long term than any drug that releases dopamine (agonists, amphetamines, reuptake inhibitors)

 

[metabrain]

I exercise as much as I can, I do weight training and walking/running, apart from my symptoms I am in excellent health according to my doctor, blood work is all good and I don't smoke and rarely ever drink. I eat well too, sleep fine at night, I don't look like the typical OSA patient because I am not fat, my OSA is probably due to a deviated septum which will probably go away when I get that fixed.

 

 

Although I concur with your observations; I know exercise, meditation, and supplements are only promote so much response. Of course they are effective, and tend to be more effective if you're already healthy, or have severe defect.

 

At the age of 17-19, I ran a lot, worked out in my room, reduced food consumption, meditation, and used dual-n-back. I would take 1 hour run on my sub-division towards the evening around 10PM. I was hallucinogenic, when complete I could feel my body rush with blood circulation, my brain felt good, and was more apt when home.

 

Pharmacology can elicit biological response not native, and many of the drugs I've used promote response I would not otherwise have. I've had very profound experience without them, but I understand I can provoke activation when wanted with drugs.

 

Dopamine agonism is the wrong way to go, unless you have parkinsons.

Go for the root cause.

Psychological problems causing it perhaps?

Exercise+Meditation, and supplements that induce potent neurogenesis will do far more long term than any drug that releases dopamine (agonists, amphetamines, reuptake inhibitors)

 

 

[kurdishfella]

dopamine can make your jaw more chiseled and eyes more attractive and possibly more things in looks. As far as other things, it can strengthen your lower back since your lower spine has a lot of dopamine neurons and thus improve motor control everywhere. It can make your skin look more beautiful too and hair. And make your spine thicker in turn making your neck bigger and head can become bigger too. etc

Edited by farshad, 18 November 2019 - 11:41 PM.

[Keizo]

From my own experience using Selegiline it was rather bad for cognitive enhancement or anything practical, unless I were to take it very infrequently. It was just an extremely unpredictable experience, sometimes get super tired, sometimes get stimulated. Usually I would feel alright on it the first 1-2 days then it would go into lethargy or annoying tension. The sublingual dosages were possibly worse. I would also say it's a rather powerful substance. Maybe my reaction would be different today, maybe I would tolerate it better, that's quite possible, but considering that I today tolerate the low dosages of prescription stimulants (currently taking equivalent of ~9 mg dexamphetamine sulfate per day, from the form of elvanse/vyvanse) and consider them a breeze to take in comparison to 1.25 mg sublingual selegiline, just from my experience alone it seems like people might be deluding themselves in thinking selegiline is safer or whatever compared to amphetamine.

 

As far as my idea of using selegiline to boost BDNF or whatever, I think there are probably safer or more pleasant substances for that sort of thing, various peptides perhaps. But I'm sure Selegiline does a lot of things (maybe too many things), and could help a lot of people if it found their particular brains.

[Elroy]

Two and a half years later, I don't take it sublingually any more. I take 1.25mg (1/4 tab) orally, which is a much lower dose than 1.25mg sublingual. I take 4 days on, 2 days off.

 

The BDNF effect is significant at this dosage and was the same at the higher dosage, i.e. my memory is better overall when I'm taking it, even on days off. My cognitive performance is a little higher on days I take it.

[BasicBiO]

Two and a half years later, I don't take it sublingually any more. I take 1.25mg (1/4 tab) orally, which is a much lower dose than 1.25mg sublingual. I take 4 days on, 2 days off.

 

The BDNF effect is significant at this dosage and was the same at the higher dosage, i.e. my memory is better overall when I'm taking it, even on days off. My cognitive performance is a little higher on days I take it.

 

I may try this route as sublingual gave me some pretty undesirable side effects...paranoia, horrible insomnia, hyper sexuality etc, but the pros were decent..enhanced cognition and motivation.

[MichaelFocus22]

1. Unfortunately, Type-2 drugs seem to be the only thing that helps with ADD-PI. What to do?

[Clavius]

1. Unfortunately, Type-2 drugs seem to be the only thing that helps with ADD-PI. What to do?

 

...Then take the Type-2 if they help. Concerta has been a life-saver for me. Quite literally maybe even. I wasn't given it to early, that's for sure.

[MichaelFocus22]

1. Clavius, I'm one who wrote that thread on ADD-PI. Remember? I simply changed the account name for identity purposes. Yes, I'm still having to take it and I hate it.  I'm referring to the medication paradox. I hope your fairing well.  

Edited by MichaelFocus22, 10 December 2019 - 07:27 AM.