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Antidepressants and Urine Detection Time

antidepressant urine detection nardil

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#1 killersoup1

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Posted 20 May 2017 - 05:33 PM


Hey guys, 

So I am stopping Nardil as I am going to be prescribed Adderall for my ADHD. My doc wants to do a urine test to ensure that the Nardil has left my system before giving me Adderall. 

The half-life of Nardil is said to be 11 hours. Roughly how long will it take before Nardil becomes undetectable in my urine? 



#2 Mind_Paralysis

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Posted 20 May 2017 - 05:57 PM

I don't quite know, mate... Never heard of urine tests which can even detect Phenelzine (nardil) - it must be a specialized test, done in a specifically equipped laboratory.

 

Checking the packaging insert reveals this:

 

https://www.pfizer.c...uspi_nardil.pdf

 

 
Metabolism
– NARDIL
®
is extensively metabolized, primarily by oxidation via
monoamine oxidase. After oral administration of -phenelzine, 73% of the administered dose was recovered in urine as phenylacetic acid and parahydroxyphenylacetic acid within 96 hours. Acetylation to N
2
-acetylphenelzine is a
minor pathway.

 

That implies that it most likely is at least detectable within 96 hours - so, go with that, to be certain.

 

Let's see... 96 hours... that's 48 + 48 hours, which is two + two days, so 4 days afterwards, then! Go with 5 days to be certain.



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#3 killersoup1

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Posted 20 May 2017 - 06:00 PM

Thank you :-)







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