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Tried a lot of nootropics none really worked - worth trying someting else?

nootropics looking worked trying question brainfog

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#1 Grandmaster

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Posted 23 August 2017 - 09:50 PM


Hello

Im a healthy and young male university student. Since january of 2014 i have tried some nootropics starting with 50x10mg dosage of noopept which seemed to work but in very sublime way. Next ones were:

-Noopept 6grams(logical thinking improvement and then short term memory impairment and brainfog after stopping dosing)

-Huperzine A(remembering dreams but not huge impact on memory or other effects)

-Phenibut(nothing, maybe getting drunk faster)

-Coluracetam(nice effect on sight and colors and then huge brainfog nearly ruined my exams)

-Pramiracetam(nothing positive, absolutely disgusting taste and nearly tongue damage because of trying it sublingual)

-PRL 8-53(worst one, hypertermia and brainfog)

-Piracetam(maybe memory improvement and made focusing easier but also brainfog)

-Vinpocetine(some memory improvement and euphoric feeling i think but vanishes fast and gives various effects depending on the day)

 

 

Natural stuff used mostly to fight BRAINFOG

-Caffeine from energy drinks and in tablets(no effect anymore since to high caffeine tolerance)

-Bacopa(first some memory improvement then nothing spectatular)

-Ginkgo biloba(nothing spectatular as bacopa, money waste)

- L-tirosine(terrible brainfog nearly ruined my trip)

-lions mane(some memory improvement but makes my brain foggy and possibly diarrhea)

-rhodiola rosea(some stimulation but nothing spectatular, makes mind bit foggy probably)

 

Currently im dosing only Ashwagandha to regulate cortisol lewels, fish oil and magnesimum. I thought brainfog was result not only of nootropics but possibly lyme disease but test showed that i might got tick bite long time ago but antnibodies level was low during the test few weeks ago.

Are there any more substances that are working differently than stuff made me feel worse so i may try them? I talk about natural stuff but also nootropics. I heard that brainfog may be result of high cortisol and that would be logical since i used energy drinks often for a long time and caffeine makes cortisol level higher.


Edited by Grandmaster, 23 August 2017 - 09:54 PM.


#2 gamesguru

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Posted 24 August 2017 - 03:03 AM

i'm with you on rhodiola being hit or miss and bacopa not working out so well either.  ginseng also works well, but it makes you a bit loopy if you take it all the time.  try to limit the green tea, maybe 3-4 days a week replacing it with gingko or something else on the off-days.  with the right lifestyle (when you sleep well or are in a good mood) you shouldn't even need anything to get you through the day.  some fructose and middle east spices have a real stimulating effect

 

another member here had lyme disease but he didn't find much solutions

 

energy drinks also contain taurine, which downregulates the GABA system.  this would be made worse by a heavy drinking habit.  my experience with racetams has been of pro-cortisol, pro-stress.  same goes for tyrosine.  i would steer clear of anything made in the lab or anything with less than 100 million users (so ginkgo, tea, ginseng can stay, but bacopa gets the cane.  i suppose the ashwagandha could stay, but i'm afraid it's pretty useless anyways)


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#3 Grandmaster

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Posted 24 August 2017 - 11:02 AM

i'm with you on rhodiola being hit or miss and bacopa not working out so well either.  ginseng also works well, but it makes you a bit loopy if you take it all the time.  try to limit the green tea, maybe 3-4 days a week replacing it with gingko or something else on the off-days.  with the right lifestyle (when you sleep well or are in a good mood) you shouldn't even need anything to get you through the day.  some fructose and middle east spices have a real stimulating effect

 

another member here had lyme disease but he didn't find much solutions

 

energy drinks also contain taurine, which downregulates the GABA system.  this would be made worse by a heavy drinking habit.  my experience with racetams has been of pro-cortisol, pro-stress.  same goes for tyrosine.  i would steer clear of anything made in the lab or anything with less than 100 million users (so ginkgo, tea, ginseng can stay, but bacopa gets the cane.  i suppose the ashwagandha could stay, but i'm afraid it's pretty useless anyways)

 

Ashwagandha makes me sleepy if i take it in the afternoon/morning but i saw some positive effects which may be result of decreasing cortisol level so i gonna continue dosing 250-750mg daily..

I probably gonna try ginseng if i gonna find it for reasonable price.

I didnt say that i have lyme, i just tested myself for it and results vere unclear in matter of possible tick bite long time ago but antibodies level responsible for fighting with new infection were low so its unlike i have it.

 

I was thinking about galantamine but since its mechanism of action is similar to huperzine's A which gave me little effects im not sure if its worth trying in my case. Anyway im still waiting for any other propositions.


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#4 Examfit Nootropic Formula

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Posted 24 August 2017 - 11:13 AM

Hello,

Examfit does work, we have many satisfied customers...but unfortunately, we must cease operations in September. Our customers and the nootropics industry have been really awesome to us, but government pressures mean we need to close our operations.

We have an extreme closing sale...e.g. 5 bottles of 30 capsules for 59€.... until the stock lasts.

www.examfit.eu

Welcome.

 

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#5 Grandmaster

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Posted 24 August 2017 - 04:41 PM

Hello,

Examfit does work, we have many satisfied customers...but unfortunately, we must cease operations in September. Our customers and the nootropics industry have been really awesome to us, but government pressures mean we need to close our operations.

We have an extreme closing sale...e.g. 5 bottles of 30 capsules for 59€.... until the stock lasts.

www.examfit.eu

Welcome.

 

I  have tried all of those 4 ingredients in "Nootrpic formula" and i wrote that they havent worked for me(its written in the first post), so that offer is a pure spam in my case.


Edited by Grandmaster, 24 August 2017 - 04:42 PM.


#6 Grandmaster

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Posted 01 October 2017 - 01:05 PM

REfresh, i bought 250mg 4% ginseng tablets and tried 500mg on empty stomach as suggested and also 30 minutes before TV program where i appeared and in both cases it gave me brainfog and slight dizzyness - waste of money once again. Also 250mg and 750mg doses gave same bad results.


Edited by Grandmaster, 01 October 2017 - 01:07 PM.


#7 jack black

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Posted 03 October 2017 - 03:02 AM

"Im a healthy and young male university student.​"

 

here is your problem: there is nothing to improve. go ahead and damage your brain first, and then maybe you will see some improvements with nootropics.

 

personally, I can see a subtle improvent in mood with piracetam at the usual dose of 1g. I can see how people prone to bipolar can go into hypomania with higher doses.


Edited by jack black, 03 October 2017 - 03:03 AM.

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#8 Grandmaster

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Posted 03 October 2017 - 11:02 AM

"Im a healthy and young male university student.​"

 

here is your problem: there is nothing to improve. go ahead and damage your brain first, and then maybe you will see some improvements with nootropics.

 

personally, I can see a subtle improvent in mood with piracetam at the usual dose of 1g. I can see how people prone to bipolar can go into hypomania with higher doses.

 

 

By healthy i mean i have no diseases, i dont drink alcohol or only really rarely and i dont smoke. I had lyme test and it showed probability by higher IgG level than normally but i havent or hadnt have any early lyme symptoms so i think having it is unlikely.

 

For me piracetam in range from 600mg to 4,8g gives no possitive cognitive effects so i discontuined dosing it and lost several dozens of cash.

Only "health" problems i currenlty deal with are brainfog and depsersonalization that vanishes in the nights/evenings - i want to cure it and maybe some new nootropic or natural substance may fix it, i heard something good about pregnenolone and that it helps with andrenal fatigue but im not sure...


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#9 msbost

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Posted 03 October 2017 - 01:10 PM

Ease up on the nootropics. Not everything that targets the brain is beneficial. Your organs are all connected, so check some bodily functions. If you can get a blood test then that would be great. Check your liver, airway canal, lung capacity, kidneys, urinary tract and reproductive system. These organs work in conjunction with each other. A fault in one might devastate other organs.  Your brain might be fine given the limitations on your organs.  If you want to achieve higher brain functioning then work on your organs, make sure that they can support a demanding brain.  Once your organs are ready then start on the nootropics that target the brain.

 

Be patient and work your away upward. 

 

Research source? mix of common sense and facts from any generic book regarding medicine and human physiology. 


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#10 jack black

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Posted 03 October 2017 - 02:43 PM

 


Only "health" problems i currenlty deal with are brainfog and depsersonalization that vanishes in the nights/evenings - i want to cure it and maybe some new nootropic or natural substance may fix it, i heard something good about pregnenolone and that it helps with andrenal fatigue but im not sure...

 

 

i didn't know nootropics were useful for "brainfog and depsersonalization."

does you search reveal otherwise?
 


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#11 Grandmaster

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Posted 03 October 2017 - 02:50 PM

 

 


Only "health" problems i currenlty deal with are brainfog and depsersonalization that vanishes in the nights/evenings - i want to cure it and maybe some new nootropic or natural substance may fix it, i heard something good about pregnenolone and that it helps with andrenal fatigue but im not sure...

 

 

i didn't know nootropics were useful for "brainfog and depsersonalization."

does you search reveal otherwise?
 

 

Thats why i wrote NOOTROPIC  and SUBSTANCES, there are dozens reports of : phosphatidylserine, l-tirosine, pregnenolone, ashvagandha  and other substances that they can remove those 2 symptoms. For me l tirosine worked other way around - terrible brainfog and i stopped using it nearly 6 months ago, phoshatidylserine whcih naturally is inside our body and brains works dosed 100-200mg before bed but nothing spectacular - it can boost dopamine, ashvagandha worked nice for lowering cortisol. IF it is effect of adrenal fatigue then pregnenolone may be best choice but i gonna look more into it.


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#12 jack black

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Posted 03 October 2017 - 02:59 PM

Thats why i wrote NOOTROPIC  and SUBSTANCES, there are dozens reports of : phosphatidylserine, l-tirosine, pregnenolone, ashvagandha  and other substances that they can remove those 2 symptoms.


 


 

 

 

 

I only saw NOOTROPIC in the title. what's with your attitude? no one here is paid to respond to your posts. if you are unpleasant, people will stop responding.


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#13 Grandmaster

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Posted 03 October 2017 - 03:01 PM

 

Thats why i wrote NOOTROPIC  and SUBSTANCES, there are dozens reports of : phosphatidylserine, l-tirosine, pregnenolone, ashvagandha  and other substances that they can remove those 2 symptoms.


 


 

 

 

 

I only saw NOOTROPIC in the title. what's with your attitude? no one here is paid to respond to your posts. if you are unpleasant, people will stop responding.

 

What is unpleasant? That i wrote 2 words with upper characters? So you reply without reading first post? Thats pure offtopic then so you can stop responding if you dont have aything valuable to write.


Edited by Grandmaster, 03 October 2017 - 03:11 PM.

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#14 JellyRev

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Posted 07 October 2017 - 06:41 PM

Basically all junk. 90% of nootropics, herbs, and minerals will do nothing I will list some that do have an effect, whether positive or negative. I will also list some drugs that I was prescribed

 

sulbutiamine: recommended dose: buzzing sensation in the brain. worth the cost? no

 

Alpha GPC: up to 1g: Some increased cognition and mood. It is the superior choline. worth the cost? no

 

PEA: 1g: A strong but brief high gone within an hour. worth it? no

 

propranolol: 60mg?: emotional blunting of anxious emotions. worth it? depends

 

Adrafinil/Modafinil: a smooth clean gain in mental faculties. worth it? yes

 

Guarana:200-400mg: caffeine with anti-depressant/euphoric properties, have to alter other caffeine consumption to adjust. worth it? maybe

 

Niacin: skin flushing and relaxation. worth it? depends

 

Celexa: 10mg: a high that last an hour. 1 hour of muscle weakness at random time during day. worth it? no

 

Buspar: recommended dose: celexa without fatigue. junk. worth it? no

 

Wellbutrin: recommended dose : more energy, jittery. worth it? depends

 

memantine: up to 60mg: brain becomes quiet while titrating upwards. no effect once stabilized. worth it? no

 

Sarcosine: 1-5g: taste like sugar, It feels like it grounds you back into your body and into reality. different than anything else:  worth it? perhaps. Has some studies behind it for depression and schizophrenia

 

Lithium Orotate: recommended dose: calming but totally unlike gabaergics and opioids. worth it? maybe

 

wrong kind of magnesium: have to go to the bathroom. worth it? mistakes were made

 

melatonin: 10mg : for sleep it can work. worth it? maybe

 

Black seed oil: had some sort of effect, not bad. worth it? depends

 

I've tried basically everything legal besides sunifram, CLITEP and a couple racetams. 

Herbs, adaptogens, oils, amino acids, trace minerals, vitamins, cholines, hormone precursors, random chemicals bond together, some really out there stuff. all did squat 


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#15 Grandmaster

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Posted 14 October 2017 - 02:00 PM

Basically all junk. 90% of nootropics, herbs, and minerals will do nothing I will list some that do have an effect, whether positive or negative. I will also list some drugs that I was prescribed

 

sulbutiamine: recommended dose: buzzing sensation in the brain. worth the cost? no

 

Alpha GPC: up to 1g: Some increased cognition and mood. It is the superior choline. worth the cost? no

 

PEA: 1g: A strong but brief high gone within an hour. worth it? no

 

propranolol: 60mg?: emotional blunting of anxious emotions. worth it? depends

 

Adrafinil/Modafinil: a smooth clean gain in mental faculties. worth it? yes

 

Guarana:200-400mg: caffeine with anti-depressant/euphoric properties, have to alter other caffeine consumption to adjust. worth it? maybe

 

Niacin: skin flushing and relaxation. worth it? depends

 

Celexa: 10mg: a high that last an hour. 1 hour of muscle weakness at random time during day. worth it? no

 

Buspar: recommended dose: celexa without fatigue. junk. worth it? no

 

Wellbutrin: recommended dose : more energy, jittery. worth it? depends

 

memantine: up to 60mg: brain becomes quiet while titrating upwards. no effect once stabilized. worth it? no

 

Sarcosine: 1-5g: taste like sugar, It feels like it grounds you back into your body and into reality. different than anything else:  worth it? perhaps. Has some studies behind it for depression and schizophrenia

 

Lithium Orotate: recommended dose: calming but totally unlike gabaergics and opioids. worth it? maybe

 

wrong kind of magnesium: have to go to the bathroom. worth it? mistakes were made

 

melatonin: 10mg : for sleep it can work. worth it? maybe

 

Black seed oil: had some sort of effect, not bad. worth it? depends

 

I've tried basically everything legal besides sunifram, CLITEP and a couple racetams. 

Herbs, adaptogens, oils, amino acids, trace minerals, vitamins, cholines, hormone precursors, random chemicals bond together, some really out there stuff. all did squat 

 

So you have similar experiences with nootropics to mine. I bought week ago pregnenolone and when taken orally in 100mg doses it have some nice procognitive effects like verbal fluency and gives some energy boost. Worth trying after all those piracetam, phenibut etc crap



#16 Rick05

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Posted 15 October 2017 - 10:18 AM

Pramiracetam taste looooool XD That feeling when you enjoy watching people suffer the same as you did XD ahahah


Anyways. Grandmaster, OP - trying so many supplements don't you worry that your dopamine levels overkill? I noticed that most of this stuff kinda works... but only if you are somewhat dopamine defficent.

#17 Grandmaster

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Posted 15 October 2017 - 12:53 PM

Pramiracetam taste looooool XD That feeling when you enjoy watching people suffer the same as you did XD ahahah


Anyways. Grandmaster, OP - trying so many supplements don't you worry that your dopamine levels overkill? I noticed that most of this stuff kinda works... but only if you are somewhat dopamine defficent.

 

Taste is not the worst thing - it didnt do shit to me so good that i got 10g for free otherwise i would be mad.

 

I thought i had dopamine deficency but since l-tyrosine(dopamine level rising stuff)made me feel like shit when i was on scientific trip, phosphatidylserine that shoud rise it gave me not much so  ithink i dont have that deficency. 



#18 Rick05

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Posted 15 October 2017 - 02:30 PM

Pramiracetam taste looooool XD That feeling when you enjoy watching people suffer the same as you did XD ahahah


Anyways. Grandmaster, OP - trying so many supplements don't you worry that your dopamine levels overkill? I noticed that most of this stuff kinda works... but only if you are somewhat dopamine defficent.

 
Taste is not the worst thing - it didnt do shit to me so good that i got 10g for free otherwise i would be mad.
 
I thought i had dopamine deficency but since l-tyrosine(dopamine level rising stuff)made me feel like shit when i was on scientific trip, phosphatidylserine that shoud rise it gave me not much so  ithink i dont have that deficency.


on a contrary. Having tried so many nootropics it didn't came to your mind that your dopamine got too high at some point? I think there is the same correlation as with real drug addicts, they also suffer the same issue after what they call "tolerance" which in my current theory is dopamine abuse rather than deficiency. Especially that you say that thyrosine made things worse for you. Thats my point- people here sometimes almost delusionally tend to avoid acknowledging that their dopamine level could actually go too high. "dopamine!? I take meth with piracetam noopept and phenibut everyday no way that I have too low level of dopamine" lol can you sense the common denial here?

I noticed similar effect after caffeine abuse. At once I had one coffee approx 3 times a week and felt great after it. After it changed to 3 times per day all the effects were crushed and I started experiencing similar effects as other real addicts. I also think that all the pleasure comes from spikes-filling the deficiencies rather than keeping them at some level

Edited by Rick05, 15 October 2017 - 02:41 PM.


#19 Mr Serendipity

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Posted 15 October 2017 - 03:12 PM

Vitamin C was the last piece of my brain puzzle. 

 

I recommend you skim through this thread, where I share studies and my experiences on it: Vitamin C for Brain & Nootropic effect

 
Basically I use to suffer from brain fog/bad clarity, and a strong mid evening slump/brain fog/energy loss. But once I started taking Vitamin C in high doses, my mind's clarity returned, my visual clarity went up, my OCD calmed down, and my energy was up; it felt like I was pretty much cured of a lot of problems after 9 days.
 
I also started taking Gingko Biloba afterward, which actually helped my memory, and gave me vague flashbacks to memories. However if I could only take 1 thing for my brain, as a mood enhancer & nootropic, it would be vitamin C hands down.
 
However I am prone to forgetting, or being lazy in taking my supplements, so my symptoms do start to creep back slowly again if I haven't taken Vitamin C for awhile. And when I do take it, I only tend to take 1g of vitamin C before bed (with the rest of my supplements), rather than 3-6g throughout the day as I would like (because higher doses gives me better results). But like I said laziness & forgetting to take them. I also think an element of forgetting how much difference something makes is another reason I forget to take my supplements. When you're ill or have symptoms, and then you take something which helps dramatically, you notice the difference, and are motivated to continue. But once you are healthy and have normal brain function, you can easily forget what got you there, and in my case, forget to take your supplements.
 
If I regularly take my supplements, I don't really feel the need to make my brain more super, because when it feels super healthy (due to taking my supplements regularly), it then feels like I don't struggle with anything brain related. The only things that really effect my brain negatively (even when taking my supplements and vitamin C regularly), are going to sleep late, and drinking and being hungover (like I am today). 
 
Anyway I recommend Vitamin C. And if you can, take 2g x 3 times a day. A lot of people say nothing more than 500mg at once does anything as the rest get's pissed out, but I call BS on that, because higher doses make a hell of a difference for me.

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#20 Grandmaster

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Posted 19 October 2017 - 05:53 PM

 

Vitamin C was the last piece of my brain puzzle. 

 

I recommend you skim through this thread, where I share studies and my experiences on it: Vitamin C for Brain & Nootropic effect

 
Basically I use to suffer from brain fog/bad clarity, and a strong mid evening slump/brain fog/energy loss. But once I started taking Vitamin C in high doses, my mind's clarity returned, my visual clarity went up, my OCD calmed down, and my energy was up; it felt like I was pretty much cured of a lot of problems after 9 days.
 
I also started taking Gingko Biloba afterward, which actually helped my memory, and gave me vague flashbacks to memories. However if I could only take 1 thing for my brain, as a mood enhancer & nootropic, it would be vitamin C hands down.
 
However I am prone to forgetting, or being lazy in taking my supplements, so my symptoms do start to creep back slowly again if I haven't taken Vitamin C for awhile. And when I do take it, I only tend to take 1g of vitamin C before bed (with the rest of my supplements), rather than 3-6g throughout the day as I would like (because higher doses gives me better results). But like I said laziness & forgetting to take them. I also think an element of forgetting how much difference something makes is another reason I forget to take my supplements. When you're ill or have symptoms, and then you take something which helps dramatically, you notice the difference, and are motivated to continue. But once you are healthy and have normal brain function, you can easily forget what got you there, and in my case, forget to take your supplements.
 
If I regularly take my supplements, I don't really feel the need to make my brain more super, because when it feels super healthy (due to taking my supplements regularly), it then feels like I don't struggle with anything brain related. The only things that really effect my brain negatively (even when taking my supplements and vitamin C regularly), are going to sleep late, and drinking and being hungover (like I am today). 
 
Anyway I recommend Vitamin C. And if you can, take 2g x 3 times a day. A lot of people say nothing more than 500mg at once does anything as the rest get's pissed out, but I call BS on that, because higher doses make a hell of a difference for me.

 

 

Since like 3 weeks ago i actually have been taking Vitamin C in 1-2g doses, powder dissolved in water. It seems to have nice effect but i would say rather moodlifting and "nice" feeling but not nootropic-like cognitive boost. I gonna try to take it more regularly now to see if effect improves over time.
 



#21 John_Woo

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Posted 24 October 2017 - 12:06 AM

One word : Methylnaphthidate

Easily available as a research compound, not available for humain consumption.

#22 kurdishfella

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Posted 15 September 2020 - 07:21 PM

you probably bought bunk/fake shit/stuff from shady people

DNA tests confirm that one-third are fake and many that are 'real' are poor quality.

https://www.bostonma...pplements-fake/

 

Canadian researchers used DNA tests to show that many pills labeled as “healing herbs” are, according to the New York Times, “little more than powdered rice and weeds.”

The researchers used DNA barcoding to conduct a blind test of the authenticity for 44 popular herbal products representing 12 companies and 30 different species of herbs, and 50 leaf samples collected from 42 herbal species. Their lab also assembled the first standard reference material herbal barcode library from 100 herbal species that were used to identify the unknown herbal products and leaf samples.

The results, which were published in October in the journal BMC medicinefound that most (59 percent) of the products tested contained DNA barcodes from plant species that were not listed on the labels. The only good news is that researchers were able to authenticate almost half (48 percent) of the products, but the bad news is that one-third of these also contained contaminants and or fillers not listed on the label.

Product substitution occurred in 30 of 44 products tested and only two of 12 companies had products without any substitution, contamination, or fillers. Just two! Some of the contaminants the researchers found are known to pose serious health risks to consumers.

The New York Times reports that two of the most common herbal supplements that Americans consume, St. Johns Wort and echinacea, were the most contaminated and poor quality, if even “real” at all:

Among their findings were bottles of echinacea supplements, used by millions of Americans to prevent and treat colds, that contained ground up bitter weed, Parthenium hysterophorus, an invasive plant found in India and Australia that has been linked to rashes, nausea and flatulence.

Two bottles labeled as St. John’s wort, which studies have shown may treat mild depression, contained none of the medicinal herb. Instead, the pills in one bottle were made of nothing but rice, and another bottle contained only Alexandrian senna, an Egyptian yellow shrub that is a powerful laxative. Gingko biloba supplements, promoted as memory enhancers, were mixed with fillers and black walnut, a potentially deadly hazard for people with nut allergies.

The study says that “most of the herbal products tested were of poor quality, including considerable product substitution, contamination and use of fillers. These activities dilute the effectiveness of otherwise useful remedies, lowering the perceived value of all related products because of a lack of consumer confidence in them.”

Researchers suggest in the study that the herbal industry should embrace DNA barcoding for authenticating herbal products through testing of raw materials used in manufacturing products. This would provide consumers with safe, high quality herbal products. So this way, the next time you buy vitamin B supplements, you actually are getting vitamin B and not anabolic steroids.

 


Edited by kurdishfella, 15 September 2020 - 07:49 PM.


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#23 Gal220

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Posted 19 September 2020 - 03:27 AM

I would try various brain nutrient formulas like Jarrow, LEF, MindLab Pro , or Qualia  +  1 teaspoon of COD liver oil like Virgin or Rosita  +  multi 2 day like Thorne  + calc/mag 1:1 ratio(dont take same time as multi).

 

Make sure you are getting

 

-proper sleep(8+ hours in pitch darkness)

 

-exercise(mix in doing 30 minute fast walks, some days do high intensity training for 15 minutes - 30 sec fast pace/30 slow on an elliptical or exercise bike)

 

 

External nootropic site for ideas - Nootropicsexpert.com

 

 


Edited by Gal220, 19 September 2020 - 03:36 AM.






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