I have a critical situation involving Citicoline that I need help with. There are so many experts on this forum that you guys seem like my only hope! I will try to make a very long story short. When I was a teenager, I was diagnosed with an imbalance of the parasympathetic & sympathetic nervous systems called "Dysautonomia." Once tipped one way or the other, my nervous system does not rebalance by itself. From birth, I used to be super-ultra sensitive to medications. In 2005, I discovered that Ashwagandha would temporarily cure the sensitivity to meds & herbs (for 24 hours when taken daily), and Chamomile would do the opposite and would temporarily increase those sensitivities. Once Ashwagandha was out of my system, all the sensitivities returned and life went on as normal.
In Fall of 2009, I took CDP Choline (Citicoline) for only a few weeks, and it down-regulated SOMETHING that has caused long-lasting changes ever since. First, the sensitivities to meds & herbs were gone ever since (even after 8 years later) and some supplements and herbs have the opposite effects than they are supposed to. Second, my face has been bloodshot red ever since, and my eyes are bloodshot as well. Third, there is a massive amount of fatigue and pain, and it's gotten so bad that I've missed months of work. There are several other effects such as visual changes in my right retina that are related as well. It almost feels like too much choline or acetylcholine is in my system 24/7.
My question is this... Assuming the batch wasn't toxic (which I'm certain it wasn't), and understanding that due to my condition, my nervous system does not regulate itself, what could CDP Choline (Citicoline) have down-regulated (or up-regulated)?