2 replies to this topic

[Daniel Cooper]

Does anyone know of a supplement or means to lower chronically high adrenaline?

 

I'm some time off of discontinuing long term use of a z-drug and I think I have some HPA axis dysregulation going on.  Horrible insomnia, anxiety, elevated BP, etc.

 

I'm doing exercise, meditation, CBT, etc. etc. but nothing seems to be breaking this lose. 

 

I did discover phosphatidylserine which can lower cortisol which does seemed to have helped, but it feels like the other side of the coin, adrenaline is elevated still. 

 

Anyone ever seen a supplement that will lower adrenaline?

 

 

[Benko]

Agree with phosphatidyl serine.

 

Go easy on the exercise.  Get sufficient sleep and try going to bed by 10 or 11PM.

 

SOMETHING TO LOOK INTO: there is apparently some interaction between melatonin and cortisol so perhaps taking melatonin might be useful or PERHAPS epitalon (a peptide)  is worth looking into: 

 

RESULTS:

Epitalon was proven to significantly stimulate melatonin synthesis in senescent monkeys in the evening, thereby normalising the circadian rhythm of cortisol secretion.

http://www.nel.edu/2...Khavinson_w.pdf

 

NB: peptides may need to be taken via injection e.g. subcut.  

 

 

 

 

[Mind_Paralysis]

Clonidine.

 

Well, it decreases norepinephrinergic tone and is HELLA sedating at least! Of course, NE is not Epinephrine, but it's close enough I say.

 

Give it a shot - rather effective against anxiety as well, has similar observable effects, but a completely different mode of action from the Z-drugs.

 

Obviously not a supplement, but it's what I think would work.

 

That, or super high-dose Magnesium-L-Threonate - the NMDA-antagonism from TRULY neuro-available magnesium is nothing to sneeze at - should put you to sleep and numb out just about every emotion you have. You don't get permanent DP/DR and emotional numbness from NMDA-antagonists like Memantine for nothin'!