Posted 15 March 2006 - 06:25 PM
I have the same. Got my Thyroid levels checked some months ago. No problem.
Ashwagandha could increase thyroid levels rather then lower them.
[Thyrotoxicosis following the use of ashwagandha]
[Article in Dutch]
van der Hooft CS, Hoekstra A, Winter A, de Smet PA, Stricker BH.
Inspectie voor de Gezondheidszorg, sectie Geneesmiddelenbewaking, Postbus 16.119, 2500 BC Den Haag.
A 32-year-old healthy woman developed thyrotoxicosis while taking capsules that contained ashwagandha herbal extract for symptoms of chronic fatigue. She was not taking any other remedies or medications. During the first few weeks, she took the capsules only occasionally without any symptoms, but after increasing the dose, she experienced clinical symptoms indicative of thyrotoxicosis. This was confirmed by laboratory assessment. The symptoms resolved spontaneously after discontinuation of the ashwagandha capsules and laboratory values normalised. To our knowledge, this relationship has not been reported previously in humans. Data from animal studies, however, have suggested that ashwagandha can increase serum concentrations of thyroid hormones. This case study suggests that thyrotoxicosis is a potentially serious side effect of ashwagandha.
Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice.
Panda S, Kar A.
School of Life Sciences, D.A. University, Indore, India.
The importance of ashwagandha root extract in the regulation of thyroid function with special reference to type-I iodothyronine 5'-monodeiodinase activity in mice liver has been investigated. Although the root extract (1.4 g kg(-1)) administered daily for 20 days by gastric intubation increased serum 3,3',5-triiodothyronine (T3) and tetraiodothyronine (T4) concentrations and hepatic glucose-6-phosphatase activity, hepatic iodothyronine 5'-monodeiodinase activity did not change significantly. Furthermore, ashwagandha root extract significantly reduced hepatic lipid peroxidation, whereas the activity of antioxidant enzymes such as superoxide dismutase and catalase were increased. These findings reveal that the ashwagandha root extract stimulates thyroidal activity and also enhances the antiperoxidation of hepatic tissue.