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NR + Vitamin C synergistic?

niagen

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#1 stefan_001

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Posted 02 January 2018 - 10:35 PM


From the Tru Niagen website FAQ:

 

NIAGEN® helps your cells produce the coenzyme NAD+ which helps a cell’s mitochondria convert fat into fuel.* Vitamin C is essential to the synthesis of carnitine which shuttles fatty acids into the mitochondria for metabolism and ATP production.

Because both vitamin C and TRU NIAGEN™ are important for cellular health and energy production, there is active research surrounding the exciting possibilities of TRU NIAGEN™ working synergistically with vitamin C and other similar nutrients.*

 

https://www.truniagen.com/faq

 

Anybody having views? I happens to be I have used vitamin C at 2 gram for some weeks recently and i did have a sense that it helps.


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#2 stefan_001

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Posted 02 January 2018 - 10:40 PM

Vitamin C as continuous supplementation may not be wise btw:

https://www.scienced...024320517306896



#3 Kevnzworld

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Posted 05 January 2018 - 11:05 PM

Vitamin C as continuous supplementation may not be wise btw:
https://www.scienced...024320517306896


I couldn't open the study, so I don't know what amounts of C were given to the rodents, or how often.
I take 500mg of C four times a day and have for almost 20 years.
My last fasting glucose test was 87. My HbA1C, 5. So it hasn't impacted or impaired my glucose tolerance.
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#4 pamojja

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Posted 05 January 2018 - 11:52 PM

 

Vitamin C as continuous supplementation may not be wise btw:
https://www.scienced...024320517306896


I couldn't open the study, so I don't know what amounts of C were given to the rodents, or how often.

 

Also rodents studies with Vitamin C are terribly confounded by their functioning continous endognous vitamin C production, which humans (along with primates, guinea-pigs and some fruit-bats) have lost due to a gene mutation. And therefore rarely applicable.


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#5 Turnbuckle

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Posted 06 January 2018 - 02:54 PM

 

Vitamin C as continuous supplementation may not be wise btw:
https://www.scienced...024320517306896


I couldn't open the study, so I don't know what amounts of C were given to the rodents, or how often.
I take 500mg of C four times a day and have for almost 20 years.
My last fasting glucose test was 87. My HbA1C, 5. So it hasn't impacted or impaired my glucose tolerance.

 

 

 

Both C and E were tested, but the levels used were rather high, and were given daily for 8 months--

 

Rats were randomly divided into three groups. Group I (n=10) served as a normal control group. Group II (vitamin C supplemented group) was supplemented with freshly prepared aqueous solution of vitamin C and was divided into three subgroups received a daily dose of 100 mg/kg, 200 mg/kg and 500 mg/kg,  respectively; 10 rats each . . . At the baseline, the fasting blood glucose levels of the vitamin C treated groups were higher 2.3, 2.2, and 2.4 folds compared to normal animals. Half an hour after the oral glucose administration, the blood glucose level reached its peak then decreased gradually to the fasting level thereafter in the normal rats. However, in the vitamin C supplemented animals, the blood glucose levels were higher by about 97.62%, 111.11%, and 122.22%, respectively above the normal one after 30 min. and failed to reach the pre-prandial level after 2 hours of the glucose load.

 

 

Vitamin E (dosed at  50 mg/kg, 100 mg/kg and 200 mg/kg) also produced elevated glucose levels.



#6 pamojja

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Posted 06 January 2018 - 03:07 PM

At the baseline, the fasting blood glucose levels of the vitamin C treated groups were higher 2.3, 2.2, and 2.4 folds compared to normal animals.

 
Some blood glucose tests, by the way, may wrongly measure high vitamin C levels as glucose.


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